Results 281 to 290 of about 88,342 (327)

Comparative aptamer profiling reveals cell surface remodeling and the emergence of a noncanonical cell surface protein under oncogenic signaling. [PDF]

RSC Chem Biol
Kakuta J, Ohba K, Ogasawara H, Okahara K, Emoto K, Sako H, Sekai M, Fujita Y, Imai T, Sakakibara Y.   +9 more
europepmc   +1 more source

Versatile Enzymatic Approach for Truncation, Labeling, and Mutation of Nucleobase-Modified Aptamers Demonstrated on Indole-Modified β-Conglutin Aptamer. [PDF]

Chembiochem
Ondruš M, Franco-Urquijo PA, Lerga TM, Mužíkova Čechová L, Bermudo Redondo MC, O Sullivan CK, Hocek M.   +6 more
europepmc   +1 more source

KSHV and cancer: understanding the oncogenic machinery for next-generation diagnostic tools and therapies. [PDF]

Arch Microbiol
da Silva JVGO, de Oliveira Santos E.
europepmc   +1 more source

Noncompetitive Fluorescence Polarization Aptamer Assay for Detecting SARS-CoV‑2 Variants. [PDF]

ACS Omega
Yu-Ting C, Suzuki R, Fujioka Y, Ishida A, Imai A, Fukuyama M, Kasuya M, Ohba Y, Fukuhara T, Shigemura K, Hibara A, Maeki M, Tokeshi M.   +12 more
europepmc   +1 more source

Recent Advances in the Detection of Aflatoxin M1 in Milk and Dairy Products. [PDF]

Biosensors (Basel)
Maurelli AM, Catucci L, Pascale M, D'Auria S, Staiano M.   +4 more
europepmc   +1 more source

Plasma proteomic profiles of patients during oral anti‐coagulant treatment with vitamin K antagonists

British Journal of Haematology, EarlyView.
Eleonora Camilleri, Bart J. M. van Vlijmen, Mettine H. A. Bos, Manfred Wuhrer, David R. Goodlett, Christoph H. Borchers, Suzanne C. Cannegieter, Nienke van Rein, Yassene Mohammed   +8 more
wiley   +1 more source

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Pushing Adenosine and ATP SELEX for DNA Aptamers with Nanomolar Affinity.

Journal of the American Chemical Society, 2023
The classical DNA aptamer for adenosine and ATP has been the most used small molecule binding aptamer for biosensing, imaging, and DNA nanotechnology. This sequence has recurred multiple times in previous aptamer selections, and all previous selections ...
Yuzhe Ding, Juewen Liu
semanticscholar   +1 more source

Strategies to manipulate the performance of aptamers in SELEX, post-SELEX and microenvironment.

Biotechnology Advances, 2022
Aptamers are short single-stranded DNA or RNA oligonucleotides isolated from randomized libraries, presenting high affinity and specificity toward targets with similar to antibodies.
Shuo Qi, Nuo Duan, I. Khan, Xiaoze Dong, Yin Zhang, Shijia Wu, Zhouping Wang   +6 more
semanticscholar   +1 more source

Nucleic Acid Aptamers for Molecular Diagnostics and Therapeutics: Advances and Perspectives.

Angewandte Chemie, 2020
The advent of SELEX (Systematic Evolution of Ligands by Exponential enrichment) technology has shown the ability to evolve artificial ligands with affinity and specificity able to meet growing clinical demand for probes that can, for example, distinguish
Long Li, Shu-juan Xu, He Yan, Xiaowei Li, H. S. Yazd, Xiang Li, Tong Huang, Cheng Cui, Jian-hui Jiang, W. Tan   +9 more
semanticscholar   +1 more source

Aptamer chemistry

Advanced Drug Delivery Reviews, 2018
Aptamers are single-stranded DNA or RNA molecules capable of tightly binding to specific targets. These functional nucleic acids are obtained by an in vitro Darwinian evolution method coined SELEX (Systematic Evolution of Ligands by EXponential enrichment).
Röthlisberger, Pascal, Hollenstein, Marcel   +1 more
openaire   +3 more sources