Results 91 to 100 of about 49,590 (251)

Perioperative von Willebrand Factor and Factor VIII Kinetics in von Willebrand Disease Patients Treated With Different Clotting Factor Concentrates

Haemophilia, EarlyView.
ABSTRACT Introduction Patients with von Willebrand disease (VWD) undergoing surgery require von Willebrand factor (VWF) and factor VIII (FVIII) supplementation for adequate haemostasis. Plasma‐derived clotting factor concentrates differ in their VWF:FVIII activity ratios: high‐ratio product (HRP, 10:1), intermediate‐ratio product (IRP, 2.4:1), and low ...
Zoë A. Gras, Geoffrey Z. L. Kuppens, Roger E. G. Schutgens   +2 more
wiley   +1 more source

Hypocoagulability among people living with HIV at Hoima Regional Referral Hospital, Western Uganda: a cross-sectional study

HIV Research & Clinical Practice
Background Coagulation abnormalities are an under-recognized complication among people living with HIV. Despite widespread antiretroviral therapy (ART), hematologic dysfunction, including coagulation and platelet abnormalities, continues to contribute to
Abdisalam Ahmed Sandeyl, Mohamed Jayte, Farah Dubad Abdi, Hassan Omar Ali, Abdisamad Guled Hersi, Zakarie Abdullahi Hussein, Venance Emmanuel Mswelo, Abdalla Ahmed Deifa, Abishir Mohamud Hirsi, Jacinto Amandua   +9 more
doaj   +1 more source

Global Diagnostics of Hemophilia and Bleeding Disorders: Insights From World Federation of Hemophilia International External Quality Assessment Scheme Program 2016–2023

Haemophilia, EarlyView.
ABSTRACT Introduction Accurate laboratory diagnosis is essential for the effective management of bleeding disorders. The World Federation of Hemophilia (WFH) International External Quality Assessment Scheme (IEQAS) provides an international platform for comparative evaluation of laboratory performance.
Silmara de Lima Montalvão, Ian Jennings, Dianne P. Kitchen, Christopher Reilly‐Stitt, Glenn F. Pierce, Andreina Tovar, Jayson Martin, Assad Haffar, Steve Kitchen   +8 more
wiley   +1 more source

Lack of correlation between heparin dose and standard clinical monitoring tests in treatment with unfractionated heparin in critically III children

Haematologica, 2007
The activated partial thromboplastin time (aPTT) and anti-Xa activity are used for monitoring unfractionated heparin (UFH) therapy in children and may not be optimal. Objective: Determine correlations of aPTT, anti-Xa and UFH dose in children.
Stefan Kuhle, Pablo Eulmesekian, Brian Kavanagh, Patricia Massicotte, Patsy Vegh, Alice Lau, Lesley G. Mitchell   +6 more
doaj   +1 more source

Pakastetun P-APTT-näytteen säilyvyys ajan funktiona [PDF]

, 2015
Tromboplastiiniaika, aktivoitu, partiaalinen (P-APTT-tutkimus) mittaa sisäistä hyytymisjärjestelmää johon vaikuttavat hyytymistekijät II, V, VIII, IX, X, XI, XII ja fibrinogeeni.
Anttila, Terhi, Halttu, Outi
core  

Massive carcinocythaemia during fulminant relapse of invasive lobular breast carcinoma

British Journal of Haematology, EarlyView.
Amina Djoudi, Roman Vion, Olivier Matray, Lucie Poisson, Cédric Paquin, Victor Bobée   +5 more
wiley   +1 more source

Perioperative Management in Persons With Haemophilia on Rebalancing Therapies: A Narrative Review

Haemophilia, EarlyView.
ABSTRACT Introduction Perioperative management in haemophilia often requires on‐demand use of clotting factor concentrates (CFC) and/or bypassing agents. Rebalancing agents (fitusiran, concizumab, marstacimab) offer a novel approach to prophylaxis by modulating endogenous anticoagulant pathways to restore haemostatic balance.
Amanda M. Henderson, Roy Khalife, Kelsey Uminski   +2 more
wiley   +1 more source

Evaluation of the APTT sensitivity to heparin of five commercial reagents: implications for therapeutic monitoring

, 1998
Heparin is an effective drug for prevention and treatment of thromboembolic conditions. Although several biological assays have been proposed for monitoring unfractionated heparin therapy, the measurement of the activated partial thromboplastin time ...
Manzato F, Grilenzoni A, Mengoni A, LIPPI, Giuseppe   +3 more
core   +1 more source

Advanced Molecular Analysis in Hemophilia A in a Single Step: Next Generation Sequencing (NGS) and Copy Number Variation (CNV) Analysis

International Journal of Laboratory Hematology, EarlyView.
ABSTRACT Background Hemophilia A, an X‐linked bleeding disorder caused by pathogenic variants in the F8 gene, requires precise genetic diagnosis for optimal management. Conventional stepwise sequence and copy number variation (CNV) analyses are time‐consuming and may leave some cases unresolved.
Enise Avci Durmusalioglu, Esra Isik, Basak Durmus Ozen, Mehmet Mert Topaloglu, Nihal Karadas, Kaan Kavakli, Melike Sezgin Evim, Tolga Aslan, Erşen Kavak, Adalet Meral Gunes, Funda Tayfun Kupesiz, Alphan Kupesiz, Fahri Sahin, Tahir Atik   +13 more
wiley   +1 more source

Shortening Activated Partial Tromboplastin Time (APTT) Between Hypertension and Nonhypertension in Diabetic Mellitus Patients with Bevacizumab Intravitreal Injection

IJRETINA (International Journal of Retina), 2019
Introduction : Bevacizumab intravitreal injection could be detectable in plasma that might interfere  the coagulopathy and hemostasis condition.
Anik Ika Winarni, Ni Luh Putu Widyasti, Natalia Christina Angsana, Rizto Wisuda Senuari, Angela Nurini Agni, Agus Supartoto, Muhammad Bayu Sasongko, Haryo Yudono   +7 more
doaj   +1 more source