Results 51 to 60 of about 45,024 (296)

Leptin May Promote Eosinophilic CRSwNP Progression by Enhancing Eosinophil Chemotaxis and Angiogenesis Under a Type 2 Inflammatory Milieu

open access: yesInternational Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background Chronic rhinosinusitis with nasal polyp (CRSwNP) is a heterogeneous Type 2 inflammatory disease characterized by enhanced eosinophilic infiltration. Both innate and adaptive immunity are involved in the onset and progression of CRSwNP.
Yuki Sonoda   +4 more
wiley   +1 more source

MONITORING OF ANTICOAGULANT THERAPY IN PATIENTS WITH DEEP VEIN THROMBOSIS

open access: yesКардиоваскулярная терапия и профилактика, 2014
Aim. To evaluate the prevalence of accomplished goal in laboratory clotting parameters for the anticoagulant therapy in deep vein thrombosis (DVT).Material and methods.
V. I. Petrov   +3 more
doaj   +1 more source

Stability of Plasma for Add-On PT and APTT Tests [PDF]

open access: yesAmerican Journal of Clinical Pathology, 1998
We conducted studies to determine at what time point an add-on prothrombin time (PT) or activated partial thromboplastin time (APTT) test can be honored on specimens that have been received in the laboratory hours earlier without yielding results with clinically significant differences from those if the test had been performed on the original unstored ...
D, Neofotistos, M, Oropeza, C H, Ts'ao
openaire   +2 more sources

Payload‐Based Clinical Pharmacology Review of Approved Antibody–Drug Conjugates: Commonalities and Considerations for Streamlined Development

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Antibody–drug conjugates (ADCs) combine the specificity of an antibody with the potency of a cytotoxic drug. Thirteen ADCs, utilizing seven unique cytotoxic payloads and targeting 11 distinct antigens, are currently approved by the US Food and Drug Administration as of June 2025, representing a rapidly growing and highly promising class of anticancer ...
Sijie Lu   +6 more
wiley   +1 more source

Abnormal Findings for PT and aPTT Tests.

open access: yes, 2015
Abnormal Findings for PT and aPTT Tests.
Kathryn McGoldrick (782286)   +17 more
core   +1 more source

Anti-Factor-Xa and Activated Partial Thromboplastin Time Concordance and Outcomes in Adults Undergoing Extracorporeal Membrane Oxygenation: A Secondary Analysis of the Pilot Low-Dose Heparin in Critically Ill Patients Undergoing Extracorporeal Membrane Oxygenation Randomized Trial

open access: yesCritical Care Explorations, 2023
OBJECTIVES:. To determine the concordance between activated partial thromboplastin time (aPTT) and anti-factor-Xa (anti-Xa) in adults undergoing extracorporeal membrane oxygenation (ECMO) and to identify the factors associated with discordant paired aPTT/
Cécile Aubron, MD, PhD   +18 more
doaj   +1 more source

Characteristics of the patients with prolonged APTT.

open access: yes, 2016
Characteristics of the patients with prolonged APTT.
Hisami Baba (3161634)   +10 more
core   +1 more source

Caution in Using the Activated Partial Thromboplastin Time to Monitor Argatroban in COVID-19 and Vaccine-Induced Immune Thrombocytopenia and Thrombosis (VITT)

open access: yesClinical and Applied Thrombosis/Hemostasis, 2021
Introduction Argatroban is licensed for patients with heparin-induced thrombocytopenia and is conventionally monitored by activated partial thromboplastin time (APTT) ratio.
Susan Guy   +5 more
doaj   +1 more source

Reference Interval Establishment for Four Coagulation Parameters Using Indirect Methods in a High‐Altitude Chinese Population: A Retrospective Real‐World Analysis

open access: yesJournal of Clinical Laboratory Analysis, EarlyView.
This study established reference intervals for APTT, PT, TT, and FIB in a Tibetan high‐altitude population using two indirect algorithms, Hoffmann and refineR. The established RIs differed significantly from those of low‐altitude regions, highlighting the need for region‐specific RIs to ensure accurate evaluation of coagulation disorders.
Banjiu Zhaxi   +15 more
wiley   +1 more source

Preliminary Evaluation of a Novel Lupus Anticoagulant Activity Assay Unaffected by Anticoagulants

open access: yesJournal of Clinical Laboratory Analysis, EarlyView.
A novel one‐step lupus anticoagulant (LA) assay based on the LA‐sensitivity ratio (LA‐SR) was developed to simplify diagnostic testing and reduce potential interference from anticoagulants. The LA‐SR method showed good agreement with guideline‐based LA testing (dRVVT and/or LA‐sensitive APTT) for the detection of LA and demonstrated limited influence ...
Ayu Hidaka   +4 more
wiley   +1 more source

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