Results 61 to 70 of about 59,602 (254)

A Refractory Leg Skin Ulcer Associated With Multiple Myeloma Successfully Treated With Plasma Exchange, Lenalidomide, and Dexamethasone

JEADV Clinical Practice, EarlyView.
ABSTRACT Multiple myeloma (MM) is a malignant plasma cell disorder that primarily presents with CRAB symptoms (calcium elevation, renal failure, anemia, and bone abnormalities). In rare cases, MM manifests with systemic complications like skin ulcers, which present management challenges. Here, we report a 78‐year‐old Japanese man with MM and refractory
Naoko Hattori, Yutaka Kuwatsuka, Tomoka Waseda, Daisuke Ehara, Koji Ando, Hiroyuki Murota   +5 more
wiley   +1 more source

Kaposiform hemangioendothelioma: Diagnosis and treatment

Pediatric Investigation, EarlyView.
Vascular endothelial growth factor‐C (VEGF‐C)/vascular endothelial growth factor receptor‐3 (VEGFR‐3) and angiopoietin‐2 (Ang‐2)/tyrosine kinase with immunoglobulin‐like and EGF‐like domain 2 (TIE2) signaling pathways play an important role in lymphangiogenesis.
Yi Tian, Yuanyuan Tian, Li Wei, Zigang Xu, Li Li, Lin Ma   +5 more
wiley   +1 more source

Exogenous Magnesium Chloride Reduces the Activated Partial Thromboplastin Times of Lupus Anticoagulant-Positive Patients. [PDF]

PLoS ONE, 2016
The activated partial thromboplastin time (APTT) assay is a basic hemostatic assay based on the time it takes for clots to form in plasma samples after the addition of calcium chloride. It is used to screen for various coagulation disorders.
Takayoshi Tokutake, Hisami Baba, Yuji Shimada, Wataru Takeda, Keijiro Sato, Yuki Hiroshima, Takehiko Kirihara, Ikuo Shimizu, Hideyuki Nakazawa, Hikaru Kobayashi, Fumihiro Ishida   +10 more
doaj   +1 more source

Safety Evaluation of an Aqueous Root and Leaf Extract of Ashwagandha (Withania somnifera)

Phytotherapy Research, EarlyView.
Sensoril, an aqueous root and leaf extract of ashwagandha showed no evidence of mutagenicity in the in vitro Ames assay, was negative in the in vitro micronucleus, in vivo mammalian bone marrow chromosome aberration assays, and was well tolerated in the rat at up to 4000 mg/kg BW/day when administered orally for a period of 90 days. The data from these
Mukesh Summan, Candace L. Doepker, Gregory P. Brorby   +2 more
wiley   +1 more source

Preclinical Toxicity Screening of Sodium Dodecanoyloxybenzenesulfonate (LOBS) as a New Alternative Biocide Using In Vitro and In Vivo Models

Environmental Toxicology, EarlyView.
ABSTRACT Sodium hypochlorite is a well‐established biocide extensively used in both living and industrial environments; however, exposure to it or improper handling can harm the human body and the environment. Thus, safer alternatives to sodium hypochlorite are required.
Seung Eui Min, Seunghee Oh, Min Seong Jang, Kang‐Hyun Han   +3 more
wiley   +1 more source

Evaluation of the Coagulant Effect of Zanjani and Latifi Viper Snake Venom Endemic in Iran

Trends in Peptide and Protein Sciences, 2016
The venom of the viper is very important in pharmaceutical usage, such as in the process of coagulation during medical care. This study aims to evaluate the coagulant factor of Latifi and Zanjani viper venom.
Milad Taherian, Hajar Yaghoobi, Mojgan Bandehpour   +2 more
doaj   +1 more source

Influence of patient factors on target plasma volume treated attainment rate during double filtration plasmapheresis in patients with hypertriglyceridemic acute pancreatitis

Therapeutic Apheresis and Dialysis, EarlyView.
Abstract Introduction This study aims to investigate patient factors affecting the rate of plasma volume target attained in hypertriglyceridemic pancreatitis (HTG‐AP) patients undergoing double filtration plasmapheresis (DFPP). Methods A retrospective analysis of 82 HTG‐AP‐interpreted patients from January 2019 to April 2024 compared target plasma ...
Hui Zhang, Chenqiang Zhu, Yunlong Wu
wiley   +1 more source

Comparison of Biocompatibility and Efficacy of Regional Citrate Anticoagulation and Unfractionated Heparin During Expanded Hemodialysis With a Medium Cut‐Off Membrane—A Randomized Trial

Artificial Organs, EarlyView.
In a randomized cross‐over trial, regional citrate anticoagulation provided superior biocompatibility over full‐dose unfractionated heparin during expanded hemodialysis with significantly lower activation of complement, granulocytes, and platelets without affecting dialysis efficiency. ABSTRACT Background Regional citrate anticoagulation (RCA) improves
Marija Malgaj Vrečko, Jernej Pajek, Jakob Gubenšek, Samo Hudoklin, Joško Osredkar, Mojca Božič Mijovski, Aleš Jerin, Jadranka Buturović‐Ponikvar   +7 more
wiley   +1 more source

Haemostatic Abnormalities in Patients with Cirrhosis and their Relation with Severity of Liver Dysfunction as Assessed by Child Pugh Score

JLUMHS, 2017
OBJECTIVE: To evaluate the hemostatic abnormalities in patients with cirrhosis and their relation with severity of liver dysfunction as assessed by Child Pugh Score.
Hanozia Hassan, Asmat Kamal Ansari , Salma Farrukh Memon   +2 more
doaj   +1 more source

Prothrombine and activated partial thromboplastin time are prolonged in hepatic cirrhosis

Universa Medicina, 2016
Background Chronic hepatitis and hepatic cirrhosis are chronic liver diseases that cause disorders of liver function, such as the formation of platelets and coagulation factors (prothrombin time/PT and activated partial thromboplastin time/APTT ...
Edward Kurnia Setiawan Limijadi, Lisyani Budi Suromo, Imam Budiwiyono   +2 more
doaj   +1 more source