Results 71 to 80 of about 1,989 (206)

Chimerization at the AQP2–AQP3 locus is the genetic basis of melarsoprol–pentamidine cross-resistance in clinical Trypanosoma brucei gambiense isolates

International Journal for Parasitology: Drugs and Drug Resistance, 2015
Aquaglyceroporin-2 is a known determinant of melarsoprol–pentamidine cross-resistance in Trypanosoma brucei brucei laboratory strains. Recently, chimerization at the AQP2–AQP3 tandem locus was described from melarsoprol–pentamidine cross-resistant ...
Fabrice E. Graf, Nicola Baker, Jane C. Munday, Harry P. de Koning, David Horn, Pascal Mäser   +5 more
doaj   +1 more source

Reviving the Skin From Within: Mechanistic Insights Into a Well‐Tolerated Dermal Filler—CPM‐HA20G

Journal of Cosmetic Dermatology, Volume 25, Issue 6, June 2026.
ABSTRACT Background Dermal fillers composed of hyaluronic acid (HA) combined with glycerol have been clinically shown to enhance skin hydration and quality; the precise mechanisms underlying their efficacy have yet to be fully elucidated. Aims Investigation of the dual hydration mechanisms, cell protection and tolerability, and tissue compatibility of ...
Kay Marquardt, Christian Hartmann, Sonja Sattler, Je‐Young Park, Ting Song Lim, Luis Alberto Parra Hernandez, Christina Wollenburg, Daniela Schäfer, Sarah Hetier‐Jaccoud, Thomas Hengl   +9 more
wiley   +1 more source

Diffusion of Glycerol through Escherichia coli Aquaglyceroporin GlpF [PDF]

, 2008
The glycerol uptake facilitator, GlpF, a major intrinsic protein found in Escherichia coli, selectively conducts water and glycerol across the inner membrane.
Schulten, Klaus, Chipot, Christophe, Tajkhorshid, Emad, Hénin, Jérôme   +3 more
core   +1 more source

Phosphate Transporters Mediate the Uptake of Monothioarsenate

Plant, Cell &Environment, Volume 49, Issue 5, Page 2628-2638, May 2026.
ABSTRACT Arsenic (As) is one of the most problematic environmental toxins. Exposure to As, predominantly via drinking water and the intake of food, represents a major human health threat. Various species of As exist in the environment, among them organic and inorganic thioarsenates.
Sebastian Haider, Sylvia Hafner, Britta Planer‐Friedrich, Stephan Clemens   +3 more
wiley   +1 more source

Aquaglyceroporins and Metalloid Transport: Implications in Human Diseases [PDF]

, 2008
Aquaglyceroporin (AQP) channels facilitate the diffusion of a wide range of neutral solutes, including water, glycerol, and other small uncharged solutes. More recently, AQPs have been shown to allow the passage of trivalent arsenic and antimony compounds. Arsenic and antimony are metalloid elements. At physiological pH, the trivalent metalloids behave
Hiranmoy, Bhattacharjee, Barry P, Rosen, Rita, Mukhopadhyay   +2 more
openaire   +2 more sources

Energetics of glycerol conduction through aquaglyceroporin GlpF [PDF]

Proceedings of the National Academy of Sciences, 2002
Aquaglyceroporin GlpF selectively conducts water and linear polyalcohols, such as glycerol, across the inner membrane of Escherichia coli . We report steered molecular dynamics simulations of glycerol conduction through GlpF, in which external forces accelerate the transchannel conduction in ...
Morten Ø, Jensen, Sanghyun, Park, Emad, Tajkhorshid, Klaus, Schulten   +3 more
openaire   +2 more sources

Aquaporin 3 (AQP3) participates in the cytotoxic response to nucleoside-derived drugs

BMC Cancer, 2012
Background Nucleoside analogs used in the chemotherapy of solid tumors, such as the capecitabine catabolite 5′-deoxy-5-fluorouridine (5′-DFUR) trigger a transcriptomic response that involves the aquaglyceroporin aquaporin 3 along with other p53-dependent
Trigueros-Motos Laia, Pérez-Torras Sandra, Casado F, Molina-Arcas Míriam, Pastor-Anglada Marçal   +4 more
doaj   +1 more source

Industrial strategies to minimize glycerol formation in ethanol fermentation by conventional Saccharomyces cerevisiae

Biofuels, Bioproducts and Biorefining, Volume 20, Issue 2, Page 1006-1020, March/April 2026.
Abstract Industrial ethanol production faces the challenge of balancing metabolic efficiency with the minimization of byproducts such as glycerol, whose formation is intensified by osmotic, thermal, oxidative, and nutritional stresses. In the literature, two main approaches stand out for modulating its synthesis: the use of genetically modified strains
Lorena M. F. Leite, Silvio R. Andrietta, Telma T. Franco   +2 more
wiley   +1 more source

Replication Data for: "Quantitative study of unsaturated transport of glycerol through aquaglyceroporin that has high affinity for glycerol" [PDF]

Coordinates, parameters, and scripts to produce the results in "Quantitative study of unsaturated transport of glycerol through aquaglyceroporin that has high affinity for glycerol".
Chen, Liao
core   +1 more source

Aquaporin‐1, aquaporin‐3 and aquaporin‐5 differentially modulate cell biophysical and biomechanical properties, impacting cell stiffness and cell–cell adhesion

The FEBS Journal, Volume 293, Issue 3, Page 806-824, February 2026.
GA text Overexpression of aquaporins AQP1, AQP3, or AQP5 in HEK‐293 T cells induced changes in cell biophysical properties and migration. Atomic force microscopy (AFM)–based force spectroscopy studies demonstrated that AQP1 overexpression increased cell stiffness and cell–cell adhesion, AQP3 augmented cell stiffness but reduced cell–cell adhesion ...
Catarina Pimpão, Filomena A. Carvalho, Inês Vieira da Silva, Andreia Barateiro, Nuno C. Santos, Graça Soveral   +5 more
wiley   +1 more source