Results 51 to 60 of about 1,989 (206)

Characterization of Leishmania donovani aquaporins shows presence of subcellular aquaporins similar to tonoplast intrinsic proteins of plants. [PDF]

PLoS ONE, 2011
Leishmania donovani, a protozoan parasite, resides in the macrophages of the mammalian host. The aquaporin family of proteins form important components of the parasite-host interface.
Neha Biyani, Swati Mandal, Chandan Seth, Malika Saint, Krishnamurthy Natarajan, Indira Ghosh, Rentala Madhubala   +6 more
doaj   +1 more source

Correlating single-molecule characteristics of the yeast aquaglyceroporin Fps1 with environmental perturbations directly in living cells [PDF]

, 2020
Membrane proteins play key roles at the interface between the cell and its environment by mediating selective import and export of molecules via plasma membrane channels.
Shashkova, Sviatlana, Leake, Mark Christian, Leake, Mark C.,, Andersson, Mikael, Shashkova, Sviatlana,, Hohmann, Stefan, Andersson, Mikael,, Leake, Mark C., Hohmann, Stefan,   +8 more
core   +1 more source

Transport proteins determine drug sensitivity and resistance in a protozoan parasite, Trypanosoma brucei

Frontiers in Pharmacology, 2015
Drug resistance in pathogenic protozoa is very often caused by changes to the ‘transportome’ of the parasites. In Trypanosoma brucei, several transporters have been implicated in uptake of the main classes of drugs, diamidines and melaminophenyl ...
Jane Claire Munday, Luca eSettimo, Luca eSettimo, Harry P de Koning   +3 more
doaj   +1 more source

Major Intrinsic Proteins in Fungi: A Special Emphasis on the XIP Subfamily

Journal of Fungi
The fungal kingdom, with an estimated five million species, has undergone extensive diversification over the past billion years and now occupies a wide array of ecological niches from terrestrial to aquatic ecosystems.
Jean-Stéphane Venisse, Gisèle Bronner, Mouadh Saadaoui, Patricia Roeckel-Drevet, Mohamed Faize, Boris Fumanal   +5 more
doaj   +1 more source

Arsenite transport by mammalian aquaglyceroporins AQP7 and AQP9 [PDF]

Proceedings of the National Academy of Sciences, 2002
Much is known about the transport of arsenite and antimonite into microbes, but the identities of mammalian transport proteins are unknown. The Saccharomyces cerevisiae FPS1 gene encodes a membrane protein homologous to the bacterial aquaglyceroporin GlpF and to mammalian aquaglyceroporins ...
Rosen, Barry P., Agre, Peter, Mukhopadhyay, Rita, Carbrey, Jennifer M., Shen, Jian, Liu, Zijuan   +5 more
openaire   +2 more sources

Modulation of Leishmania major aquaglyceroporin activity by a mitogen-activated protein kinase [PDF]

, 2012
Leishmania major aquaglyceroporin (LmjAQP1) adventitiously facilitates the uptake of antimonite [Sb(III)], an active form of Pentostam® or Glucantime®, which are the first line of defence against all forms of leishmaniasis.
Veide Vilg, Jenny,, Kruse, Martin, Tamás, Markus J, Veide Vilg, Jenny, Tam\ue1s, Markus J., Bhattacharjee, Hiranmoy, Sharma, Mansi, Wang, Yong, Sander-Juelch, Claudia, Tamás, Markus J.,, Mandal, Goutam, Munro, Laura A, Vilg, Jenny Veide, Mukhopadhyay, Rita, Wiese, Martin   +14 more
core   +1 more source

Subchronic Exposure to Arsenic and Nickel Triggers Nitrosative Stress and Histological Alterations in the Rat Liver

Journal of Applied Toxicology, EarlyView.
ABSTRACT Environmental exposure to heavy metals poses a threat to human health. Several studies documented harmful effects on the liver after arsenic and nickel exposure at concentrations beyond permissible limits. Nevertheless, the impact of a simultaneous exposure to both elements on hepatic biochemistry and histology remains unelucidated. Therefore,
Thainá Iasbik‐Lima, Luiz Otávio Guimarães‐Ervilha, Isabela Pereira da Silva Bento, Renê Chagas da Silva, Mariana Machado‐Neves   +4 more
wiley   +1 more source

Aquaglyceroporins, one channel for two molecules

Biochimica et Biophysica Acta (BBA) - Bioenergetics, 2002
In the light of the recently published structure of GlpF and AQP1, we have analysed the nature of the residues which could be involved in the formation of the selectivity filter of aquaporins, glycerol facilitators and aquaglyceroporins. We demonstrate that the functional specificity for major intrinsic protein (MIP) channels can be explained on one ...
Thomas, D., Bron, P., Ranchy, G., Duchesne, L., Cavalier, A., Rolland, J., Raguenes-Nicol, C., Hubert, J., Haase, W., Delamarche, C.   +9 more
openaire   +3 more sources

Saccharomyces cerevisiae exhibiting a modified route for uptake and catabolism of glycerol forms significant amounts of ethanol from this carbon source considered as ‘non-fermentable’

Biotechnology for Biofuels, 2019
Background Due to its inevitable formation during biodiesel production and its relatively high degree of reduction, glycerol is an attractive carbon source for microbial fermentation processes.
Maximilian R. Aßkamp, Mathias Klein, Elke Nevoigt   +2 more
doaj   +1 more source

Implication of Renal Aquaporin-3 in Fructose-Induced Metabolic Syndrome and Melatonin Protection [PDF]

Journal of Clinical and Diagnostic Research, 2016
Introduction: Metabolic Syndrome (MetS) can be induced by ingestion of large amounts of fructose as a consequence of oxidative stress and dyslipidemia.
Suzy Fayez Ewida, Dalia Rifaat Al-Sharaky   +1 more
doaj   +1 more source