Results 51 to 60 of about 1,538 (126)

Industrial strategies to minimize glycerol formation in ethanol fermentation by conventional Saccharomyces cerevisiae

Biofuels, Bioproducts and Biorefining, Volume 20, Issue 2, Page 1006-1020, March/April 2026.
Abstract Industrial ethanol production faces the challenge of balancing metabolic efficiency with the minimization of byproducts such as glycerol, whose formation is intensified by osmotic, thermal, oxidative, and nutritional stresses. In the literature, two main approaches stand out for modulating its synthesis: the use of genetically modified strains
Lorena M. F. Leite, Silvio R. Andrietta, Telma T. Franco   +2 more
wiley   +1 more source

Aquaporin‐1, aquaporin‐3 and aquaporin‐5 differentially modulate cell biophysical and biomechanical properties, impacting cell stiffness and cell–cell adhesion

The FEBS Journal, Volume 293, Issue 3, Page 806-824, February 2026.
GA text Overexpression of aquaporins AQP1, AQP3, or AQP5 in HEK‐293 T cells induced changes in cell biophysical properties and migration. Atomic force microscopy (AFM)–based force spectroscopy studies demonstrated that AQP1 overexpression increased cell stiffness and cell–cell adhesion, AQP3 augmented cell stiffness but reduced cell–cell adhesion ...
Catarina Pimpão, Filomena A. Carvalho, Inês Vieira da Silva, Andreia Barateiro, Nuno C. Santos, Graça Soveral   +5 more
wiley   +1 more source

Synergistic roles of aquaporin 5 and intra‐ and extracellular carbonic anhydrases in promoting CO2 diffusion across the Xenopus oocyte plasma membrane

The Journal of Physiology, Volume 604, Issue 3, Page 1174-1234, 1 February 2026.
Abstract figure legend Fick's law: JCO2=PM*,CO2±hAQP5·([CO2]os±bCA−[CO2]is±hCAII)TransmembraneCO2gradient${J}_{{\mathrm{CO}}_{2}}=\underset{\pm \mathrm{hAQP}5}{\underset{}{{P}_{\mathrm{M}^\ast ,{\mathrm{CO}}_{2}}}}\, \cdot \underset{\mathrm{Transmembrane}\ {\mathrm{CO}}_{2}\ \mathrm{gradient}}{\underset{}{(\underset{\pm \mathrm{bCA}}{\underset ...
Deng‐Ke Wang, Fraser J. Moss, Walter F. Boron   +2 more
wiley   +1 more source

Cryopreservation of Anopheles gambiae Larvae

Advanced Biology, Volume 10, Issue 1, January 2026.
Advancements in vector control methods have resulted in a rapidly growing collection of critically important mosquito strains necessitating the development of cryopreservation protocols to minimize the risk of genetic drift, cross‐contamination, or catastrophic loss.
Purva Joshi, Zachary Chau, Abby Callahan‐Muller, Vincent O. Nyasembe, Kala Acha, Ellen M. Dotson, Mehmet Toner, Rebecca D. Sandlin   +7 more
wiley   +1 more source

Mechanism of CO2 and NH3 transport through human aquaporin 1: Evidence for parallel CO2 pathways

The Journal of Physiology, Volume 604, Issue 1, Page 336-365, 1 January 2026.
Abstract figure legend The figure illustrates the permeation pathways for CO2, NH3 and H2O through AQP1. The panel on the left, with the wild‐type protein under control conditions, CO2 moves through monomeric pores (2 of 4 shown) but predominantly via an alternate pathway (perhaps the central pore of the tetramer).
Raif Musa‐Aziz, R. Ryan Geyer, Seong‐Ki Lee, Fraser J. Moss, Walter F. Boron   +4 more
wiley   +1 more source

Trypanosomatid Aquaporins: Roles in Physiology and Drug Response

Diseases, 2013
In the class Kinetoplastida, we find an order of parasitic protozoans classified as Trypanosomatids. Three major pathogens form part of this order, Trypanosoma cruzi, Trypanosoma brucei, and Leishmania, which are responsible for disease and fatalities in
Goutam Mandal, Jose F. Orta, Mansi Sharma, Rita Mukhopadhyay   +3 more
doaj   +1 more source

Instability of aquaglyceroporin (AQP) 2 contributes to drug resistance in Trypanosoma brucei.

PLoS Neglected Tropical Diseases, 2020
Defining mode of action is vital for both developing new drugs and predicting potential resistance mechanisms. Sensitivity of African trypanosomes to pentamidine and melarsoprol is predominantly mediated by aquaglyceroporin 2 (TbAQP2), a channel ...
Juan F Quintana, Juan Bueren-Calabuig, Fabio Zuccotto, Harry P de Koning, David Horn, Mark C Field   +5 more
doaj   +1 more source

The Concise Guide to PHARMACOLOGY 2025/26: Ion channels

British Journal of Pharmacology, Volume 182, Issue S1, Page S152-S241, December 2025.
The Concise Guide to Pharmacology 2025/26 marks the seventh edition in this series of biennial publications in the British Journal of Pharmacology. Presented in landscape format, the guide provides a comparative overview of the pharmacology of drug target families. The concise nature of the Concise Guide refers to the style of presentation, being clear,
Stephen P. H. Alexander, Jörg Striessnig, Alasdair J. Gibb, Alistair A. Mathie, Emma L. Veale, Eamonn Kelly, Chloe J. Peach, Jane F. Armstrong, Elena Faccenda, Simon D. Harding, Christopher Southan, Jamie A. Davies, Richard W. Aldrich, Bernard Attali, Austin M. Baggetta, Elvir Becirovic, David J. Beech, Martin Biel, Roslyn M. Bill, Ana I. Caceres, William A. Catterall, Han Chow Chua, Alex C. Conner, Henry Danahay, Paul Davies, Katrien De Clerq, Markus Delling, Francesco Di Virgilio, Simonetta Falzoni, Wei Fang, Stefanie Fenske, Anna Fortuny‐Gomez, Samuel Fountain, George K. Chandy, Mohammad‐Reza Ghovanloo, Steve A. N. Goldstein, Martin Gosling, Christian Grimm, Stephan Grissmer, Kotdaji Ha, Tim G. Hales, Verena Hammelmann, Israel Hanukoglu, Meiqin Hu, Ad P. Ijzerman, Sairam V. Jabba, Mike Jarvis, Anders A. Jensen, Sven E. Jordt, Leonard K. Kaczmarek, Stephan Kellenberger, Charles Kennedy, Brian King, Philip Kitchen, Qiang Liu, Joseph W. Lynch, Rian W. Manville, Jessica Meades, Verena Mehlfeld, Annette Nicke, Stefan Offermanns, Edward Pérez‐Reyes, Leigh D. Plant, Stephan A. Pless, Lachlan D. Rash, Dejian Ren, Hussein N. Rubaiy, Mootaz M. Salman, Werner Sieghart, Lucia G. Sivilotti, Trevor G. Smart, Terrance P. Snutch, Paolo Tammaro, Jinbin Tian, James S. Trimmer, Charlotte Van den Eynde, Paola Vergani, Joris Vriens, Stephen G. Waxman, Aguan D. Wei, Brenda T. Winn, Heike Wulff, Haoxing Xu, Fan Yang, Lixia Yue, Xiaoli Zhang, Michael Zhu   +86 more
wiley   +1 more source

Freeze‐tolerant frogs accumulate cryoprotectants using photoperiod: A potential ecological trap

Journal of Animal Ecology, Volume 94, Issue 11, Page 2255-2266, November 2025.
Climate change is disrupting the reliability of photoperiod as a cue signalling seasonal changes in temperature. We show that gray treefrogs under a late‐season photoperiod accumulated large reserves of ‘antifreeze’ and exhibited greater cold tolerance.
Troy C. Neptune, Diana C. Koester, Michael F. Benard   +2 more
wiley   +1 more source

Glutamate reduces glucose utilization while concomitantly enhancing AQP9 and MCT2 expression in cultured rat hippocampal neurons

Frontiers in Neuroscience, 2014
The excitatory neurotransmitter glutamate has been reported to have a major impact on brain energy metabolism. Using primary cultures of rat hippocampal neurons, we observed that glutamate reduces glucose utilization in this cell type, suggesting ...
Fabio eTescarollo, Fabio eTescarollo, Luciene eCovolan, Luc ePellerin   +3 more
doaj   +1 more source