Results 21 to 30 of about 1,373 (155)
Sex-Specific Effect of High-Fat Diet on Glycerol Metabolism in Murine Adipose Tissue and Liver
Frontiers in Endocrinology, 2020 Obesity is associated with increased plasma glycerol levels. The coordinated regulation of glycerol channels in adipose tissue (AQP7) and the liver (AQP9) has been suggested as an important contributor to the pathophysiology of type-2-diabetes mellitus ...
Francesco Maria Iena +6 more
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Aquaglyceroporins Are Differentially Expressed in Beige and White Adipocytes [PDF]
International Journal of Molecular Sciences, 2020 Browning of white adipocytes has been proposed as a powerful strategy to overcome metabolic complications, since brown adipocytes are more catabolic, expending energy as a heat form. However, the biological pathways involved in the browning process are still unclear.
Inês Vieira da Silva +5 more
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Aquaporin-10 represents an alternative pathway for glycerol efflux from human adipocytes. [PDF]
PLoS ONE, 2013 BACKGROUND: Glycerol outflow from adipocytes has been considered for a decade to be mediated by aquaporin-7, an aquaglyceroporin highly expressed in the adipose tissue. Its involvement in glycerol metabolism has been widely studied also in humans. Recent
Umberto Laforenza +2 more
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Cellular Physiology and Biochemistry, 2013 Background: Trypanosoma brucei is a primitive parasitic protozoan that thrives in diverse environments such as the midgut of the tsetse fly and the blood of a mammalian host.
Néstor L. Uzcátegui +6 more
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Methylarsonous Acid Transport by Aquaglyceroporins
Environmental Health Perspectives, 2006 Many mammals methylate trivalent inorganic arsenic in liver to species that are released into the bloodstream and excreted in urine and feces. This study addresses how methylated arsenicals pass through cell membranes. We have previously shown that aquaglyceroporin channels, including Escherichia coli GlpF, Saccharomyces cerevisiae Fps1p, AQP7, and ...
Liu, Zijuan +2 more
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Communications Biology, 2021 Marc Catalán-Garcia et al. examine evolutionary divergence of aquaglyceroporins (GLPs) in copepods, observing that these genes are subject to high rates of gene duplication across species.
Marc Catalán-García +5 more
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Implications of Aquaglyceroporin 7 in Energy Metabolism [PDF]
International Journal of Molecular Sciences, 2018 The aquaglyceroporin AQP7 is a pore-forming transmembrane protein that facilitates the transport of glycerol across cell membranes. Glycerol is utilized both in carbohydrate and lipid metabolism. It is primarily stored in white adipose tissue as part of the triglyceride molecules.
Lebeck, Janne; id_orcid 0000-0003-1716-0417 +1 more
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AQPX-cluster aquaporins and aquaglyceroporins are asymmetrically distributed in trypanosomes
Communications Biology, 2021 Tesan et al. describe a large number of aquaporin protein sequences of the kinetoplastids using sequence similarity networks and phylogenetic trees.
Fiorella Carla Tesan +3 more
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Mammalian aquaglyceroporin function in metabolism
Biochimica et Biophysica Acta (BBA) - Biomembranes, 2016 Aquaglyceroporins are integral membrane proteins that are permeable to glycerol as well as water. The movement of glycerol from a tissue/organ to the plasma and vice versa requires the presence of different aquaglyceroporins that can regulate the entrance or the exit of glycerol across the plasma membrane.
Laforenza U., Bottino C., Gastaldi G.
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Estrogen Modulates Glycerol Permeability in Sertoli Cells through Downregulation of Aquaporin-9
Cells, 2018 High 17β-Estradiol (E2) levels are known to cause alterations of spermatogenesis and environments throughout the male reproductive tract. Sertoli cells (SCs) ensure an adequate environment inside the seminiferous tubule. Glycerol stands as essential
Raquel L. Bernardino +6 more
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