Results 91 to 100 of about 11,586,786 (268)

Effects of an Aquaporin 4 Inhibitor, TGN-020, on Murine Diabetic Retina

open access: yesInternational Journal of Molecular Sciences, 2020
Purpose: To investigate the effect of a selective aquaporin 4 (AQP4) inhibitor, 2-(nicotinamide)-1,3,4-thiadiazole (TGN-020), on the expression of vascular endothelial growth factor (VEGF) and reactive oxygen species (ROS) production, as well as on the ...
Shou Oosuka   +7 more
semanticscholar   +1 more source

Physiological Roles of Aquaporin-4 in Brain

open access: yesPhysiological Reviews, 2013
Aquaporin-4 (AQP4) is one of the most abundant molecules in the brain and is particularly prevalent in astrocytic membranes at the blood-brain and brain-liquor interfaces. While AQP4 has been implicated in a number of pathophysiological processes, its role in brain physiology has remained elusive.
Ole Petter Ottersen, Erlend A. Nagelhus
openaire   +3 more sources

Heterogeneity evaluation of multi-high b-value apparent diffusion coefficient on cerebral ischemia in MCAO rat

open access: yesFrontiers in Neuroscience, 2022
PurposeTo assess brain damage in a rat model of cerebral ischemia based on apparent diffusion coefficient (ADC) data obtained from multi-high b-values and evaluate the relationship between Aquaporin 4 (AQP4) expression and ADC.MethodsThirty eight male ...
Liwei Shi   +13 more
doaj   +1 more source

Brain Aquaporin 4 in Hyperammonemia [PDF]

open access: yes, 2010
In liver failure, congenital enzymopathies of the urea cycle, and other disorders, ammonia may not be properly detoxified and thus hyperammonemia ensues.
Cauli, Omar
core  

Conjugated linoleic acid reduces permeability and fluidity of adipose plasma membranes from obese Zucker rats [PDF]

open access: yes, 2010
NOTICE: this is the author’s version of a work that was accepted for publication in Biochemical and Biophysical Research Communications. Changes resulting from the publishing process, such as peer review, editing, corrections, structural formatting, and ...
Lopes, Paula A.   +7 more
core   +1 more source

Lung fluid transport in aquaporin-1 and aquaporin-4 knockout mice [PDF]

open access: yesJournal of Clinical Investigation, 1999
The mammalian lung expresses water channel aquaporin-1 (AQP1) in microvascular endothelia and aquaporin-4 (AQP4) in airway epithelia. To test whether these water channels facilitate fluid movement between airspace, interstitial, and capillary compartments, we measured passive and active fluid transport in AQP1 and AQP4 knockout mice. Airspace-capillary
Michael A. Matthay   +5 more
openaire   +3 more sources

Expression Analysis of Sugarcane Aquaporin Genes under Water Deficit

open access: yesJournal of Nucleic Acids, 2013
The present work is a pioneer study specifically addressing the aquaporin transcripts in sugarcane transcriptomes. Representatives of the four aquaporin subfamilies (PIP, TIP, SIP, and NIP), already described for higher plants, were identified. Forty-two
Manassés Daniel da Silva   +9 more
doaj   +1 more source

COVID-19 associated with encephalomyeloradiculitis and positive anti-aquaporin-4 antibodies: Cause or coincidence?

open access: yesMultiple Sclerosis, 2020
Neurologic complications are being recognized as important outcomes of coronavirus disease 2019 (COVID-19). Pathogenesis is varied and incompletely understood, and may include neuroinvasion, indirect post-infectious neuroinflammation, and cerebrovascular
D. Corrêa   +4 more
semanticscholar   +1 more source

Aquaporin-4 Functionality and Virchow-Robin Space Water Dynamics: Physiological Model for Neurovascular Coupling and Glymphatic Flow. [PDF]

open access: yes, 2017
The unique properties of brain capillary endothelium, critical in maintaining the blood-brain barrier (BBB) and restricting water permeability across the BBB, have important consequences on fluid hydrodynamics inside the BBB hereto inadequately ...
Igarashi, Hironaka   +3 more
core   +1 more source

A proteomic and phosphoproteomic analysis of Oryza sativa plasma membrane and vacuolar membrane [PDF]

open access: yes, 2008
Proteomic and phosphoproteomic analyses of rice shoot and root tonoplast-enriched and plasma membrane-enriched membrane fractions were carried out to look at tissue-specific expression, and to identify putative regulatory sites of membrane transport ...
Ahn   +38 more
core   +1 more source

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