Results 111 to 120 of about 85,347,708 (300)

Distinct serum and cerebrospinal fluid cytokine and chemokine profiles in autoantibody-associated demyelinating diseases

Multiple Sclerosis Journal - Experimental, Translational and Clinical, 2019
Background Demyelinating diseases of the central nervous system associated with autoantibodies against aquaporin-4 and myelin-oligodendrocyte-glycoprotein are mediated by different immunopathological mechanisms compared to multiple sclerosis.
Livia S Hofer, Sara Mariotto, Sebastian Wurth, Sergio Ferrari, Chiara R Mancinelli, Rachele Delogu, Salvatore Monaco, Alberto Gajofatto, Carmen Schwaiger, Kevin Rostasy, Florian Deisenhammer, Romana Höftberger, Thomas Berger, Markus Reindl   +13 more
doaj   +1 more source

Biomarkers of lung congestion and injury in acute heart failure

ESC Heart Failure, Volume 12, Issue 2, Page 781-789, April 2025.
Abstract Acute heart failure (AHF) classification and management are primarily based on lung congestion and/or hypoperfusion. The quantification of the vascular and tissue lung damage is not standard practice though biomarkers of lung injury may play a relevant role in this context.
Marco Guazzi, Gabriele Novello, Francesca Bursi, Anna Caretti, Noemi Furlotti, Ross Arena, Paola Argiento, Julio Núñez, Antoni Bayes‐Genis, Marco Metra   +9 more
wiley   +1 more source

A case report: Diagnosis and treatment of idiopathic hypertrophic pachymeningitis

Ibrain, Volume 11, Issue 1, Page 112-116, Spring 2025.
We reported a case of idiopathic hypertrophic dura meningitis diagnosed in our hospital. The patient repeatedly suffered from headaches, followed by blurred vision in the right eye. During this period, multiple sclerosis was considered for diagnosis, and it improved after hormone treatment.
Zhong Luo, Piao Cao, Jing‐Qing Xu, Rong Yan, Jian Wang, Tao Liang, Ya Chen, Zu‐Cai Xu   +7 more
wiley   +1 more source

Bidirectional Pathological Axis Between Alzheimer's Disease and Circadian Rhythm Disturbance: Mechanisms and Therapeutic Strategies

iNew Medicine, EarlyView.
This graphical abstract illustrates a bidirectional vicious cycle between Alzheimer’s disease (AD) and circadian rhythm disturbance (CRD). On the one hand, AD pathology, including amyloid‐β (Aβ) plaque deposition and tau hyperphosphorylation, may damage the suprachiasmatic nucleus (SCN) and disrupt melatonin signaling, leading to sleep fragmentation ...
Jiajia Qin, Xianfeng Yu, Yayu Wang, Xiaohan Song, Yuehua Wang, Zhixin Wang, Wei Miao, Xudong Yang, Jiajia Zhu, Xiaoqun Zhu, Maria‐Trinidad Herrero   +10 more
wiley   +1 more source

The distribution characteristics of aquaporin 4 antibody in patients with neuromyelitis optica and the relationship between aquaporin 4 antibody and oligoclonal bands

Chinese Journal of Contemporary Neurology and Neurosurgery, 2014
Objective To explore the distribution characteristics of aquaporin 4 (AQP4) antibody in serum and cerebrospinal fluid (CSF) of neuromyelitis optica (NMO) patients, and to analyze the relationship between AQP4 antibody and oligoclonal bands (OB) in CSF
Hui-cong NIU, Xing-hu ZHANG
doaj  

Complement-dependent bystander injury to neurons in AQP4-IgG seropositive neuromyelitis optica

Journal of Neuroinflammation, 2018
Background Aquaporin-4-immunoglobulin G (AQP4-IgG) seropositive neuromyelitis optica spectrum disorder (herein called NMO) is an autoimmune disease of the central nervous system in which AQP4-IgG binding to AQP4 on astrocytes results in complement ...
Tianjiao Duan, Alex J. Smith, Alan S. Verkman   +2 more
doaj   +1 more source

Detection of aquaporin-4 antibody using aquaporin-4 extracellular loop-based carbon nanotube biosensor for the diagnosis of neuromyelitis optica [PDF]

, 2015
Here we propose a carbon nanotube (CNT) field-effect transistor (FET) functionalized with aquaporin-4 (AQP4) extracellular loop peptides for the rapid detection of AQP4 antibody without pretreatment.
Park, Kyung Seok, Kim, Daesan, Son, Manki, Park, Tai Hyun, Hong, Seunghun   +4 more
core   +1 more source

Body Size and Habitat Association as Determinants for Water Balance, Temperature Relations, and Behavioral Performance in Leptodactylid Frogs

Journal of Experimental Zoology Part A: Ecological and Integrative Physiology, EarlyView.
ABSTRACT The association between species' habitat preferences (e.g., aquatic, terrestrial, arboreal) and traits related to body temperature regulation and water balance has been relatively well studied in anurans. However, whether such associations hold for species occupying the same general habitat while differing in other relevant functional ...
Luis M. Senzano, Rodolfo O. Anderson, Rodrigo S. B. Gavira, Enzo G. Pizzi Miranda, Denis V. Andrade   +4 more
wiley   +1 more source

Old disease, new twist

Journal of Hospital Medicine, EarlyView.
Abstract An 81‐year‐old man with a history of high‐grade urothelial carcinoma of the bladder and ureter on treatment with atezolizumab and tiragolumab presented to the emergency department with 5 months of malaise, generalized weakness, and fatigue and 2 weeks of subjective fevers. One month prior to presentation, he received an empiric 9‐day course of
Hadi Roudsari, Gurpreet Dhaliwal, Anand D. Jagannath, Alan H. Baik, Sam Brondfield   +4 more
wiley   +1 more source

Distribution of aquaporin-4 water channel expression within rat kidney

, 1995
The aquaporins are a family of transmembrane proteins that function as molecular water channels. Recently, a mercurial-insensitive water channel [MIWC or aquaporin-4 (AQP4)] has been cloned, and its mRNA was found to be expressed strongly in kidney ...
S. Nielsen, M. A. Knepper, J. Terris, D. Marples, C. A. Ecelbarger   +4 more
core   +1 more source