Results 131 to 140 of about 12,794,158 (296)

The developmental history of study on neuromyelitis optica

Chinese Journal of Contemporary Neurology and Neurosurgery, 2014
In 19th century, neuromyelitis optica (NMO) indicated optic neuritis and myelitis with simultaneous onset of both sides. Later studies proposed that the onset of right or left side optic neuritis could be separated by weeks, months even years.
Kai FENG, Xing-hu ZHANG, Xian-hao XU
doaj  

Enhanced 3D Filter‐Exchange Imaging Using Multi‐Slab Acquisition

Magnetic Resonance in Medicine, EarlyView.
ABSTRACT Purpose Starting from the implementation of a single‐slice FEXI sequence, a 3D method was developed to accelerate a FEXI experiment and acquire a multi‐slice volume. Methods 3D multi‐slab FEXI divides the volume of interest into different slabs.
Jacopo Frignani, Athanasia Kaika, Ben Danzer, Franz Schilling   +3 more
wiley   +1 more source

Uptake, metabolism, and bioremediation of neonicotinoid insecticides in soil–plant systems: A review

New Plant Protection, EarlyView.
This review summarizes the uptake and metabolic transformation of neonicotinoid insecticides in plants, showing that some metabolites exhibit higher toxicity. We also critically assess promising bioremediation strategies using microbes and plant–microbe interactions to reduce residue contamination.
Wenwen Guo, Jiayue Liu, Yichen Yang, Hui Li, Runan Li, Yuanbo Li   +5 more
wiley   +1 more source

Aquaporin-4-IgG-seropositive neuromyelitis optica spectrum disorders: progress of experimental models based on disease pathogenesis

Neural Regeneration Research
Neuromyelitis optica spectrum disorders are neuroinflammatory demyelinating disorders that lead to permanent visual loss and motor dysfunction. To date, no effective treatment exists as the exact causative mechanism remains unknown.
Li Xu, Huiming Xu, Changyong Tang
doaj   +1 more source

Study on aquaporin 1 and aquaporin 4 in the cerebrospinal fluid of patients with bacterial and viral meningitis compared to a healthy control group

, 2016
Hintergrund: Die bakterielle Meningitis hat eine Letalität von 10-20%. Das Hirnödem stellt bei ca. 14 % der Erkrankten eine prognosebestimmende Komplikation dar.
Eckert, Isabel
core   +1 more source

Molecular Biomarkers in Meniere's Disease: A Scoping Review of Current Evidence

Otolaryngology–Head and Neck Surgery, EarlyView.
Abstract Objective Meniere's disease is a complex chronic inner ear condition that is characterized by vertigo, tinnitus, aural fullness, and progressive hearing loss. Currently, diagnostic strategies remain symptom‐driven, and treatments focus on management of discrete episodes rather than targeting underlying pathophysiology.
Hamza Kamran, Zaharadeen Jimoh, Tariq Issa, Nahla A. Gomaa   +3 more
wiley   +1 more source

Host‐induced silencing of the Minc09294 effector gene impairs Meloidogyne incognita and M. Enterolobii infection

Pest Management Science, EarlyView.
Host‐induced gene silencing of the effector candidate Minc09294 significantly impairs Meloidogyne incognita parasitism, markedly reducing gall formation, reproduction, and the development of specialized giant cells, with partial cross‐species effects on M.
João Pedro Abreu‐Sousa, Thuanne Pires Ribeiro, Daniele Heloisa Pinheiro, Valdeir Junio Vaz Moreira, Luanna Pinheiro Alburquerque Freitas Bezerra, Júlia Moura Rosário Santana, Lays Antunes Teixeira, Maria Eugenia Lisei‐de‐Sa, Deyse Alexandra Rosero Alpala, Manoely Abreu Reis, Isabela Tristan Lourenço‐Tessutti, Leonardo Lima Pepino Macedo, Carolina Vianna Morgante, Maria Cristina Mattar Silva, Marcos Fernando Basso, Janice de Almeida‐Engler, Maria Fatima Grossi‐de‐Sa   +16 more
wiley   +1 more source

Aquaporin-4 overexpression in rat ALS model.

, 2009
Onset of motoneuron death characterizing amyotrophic lateral sclerosis (ALS) is closely linked to modified astrocytic and glial environments. Here, we show that in the spinal cord from transgenic rat overexpressing mutated human SOD1, aquaporin-4 mRNA ...
Soyfoo, Muhammad Shahnawaz, Michèle Authelet, Pochet, Roland, Robert De Decker, De Decker, Robert, Muhammad Shahnawaz Soyfoo, Danijela Bataveljic, Christine Delporte, Roland Pochet, Charles Nicaise, Delporte, Christine, Shahnawaz Soyfoo, Muhammad, Nicaise, Charles, Bataveljic, Danijela, Authelet, Michèle   +14 more
core   +1 more source

Carbon dots as a smart nanoplatform for the blood‐brain barrier penetration and ischemic stroke therapy

Responsive Materials, EarlyView.
This review presents the structure and transport routes of the blood‐brain barrier, summarizes the ischemic stroke pathophysiological cascade, and discusses the BBB‐crossing mechanisms and multitarget therapeutic effects of carbon dots, demonstrating their promising theranostic potential for ischemic stroke.
Yanhan Huang, Xuan Hou, Haiping Zhao, Qi Kong, Xiayan Wang, Xiaokun Geng, Zaicheng Sun   +6 more
wiley   +1 more source

Differences in distribution and regulation of astrocytic aquaporin-4 in human and rat hydrocephalic brain

, 2013
Aims:  Aqua¬porin-4 is the most abundant cellular water channel in brain and could be a molecular basis for a cerebrospinal fluid absorption route additional to the arachnoid villi.
Holst, Anders Vedel, Laursen, Henning, Skjolding, Anders Daehli, Broholm, Helle, Juhler, Marianne   +4 more
core   +1 more source