Results 121 to 130 of about 11,586,786 (268)
Chinese Journal of Contemporary Neurology and Neurosurgery, 2014 Objective To explore the distribution characteristics of aquaporin 4 (AQP4) antibody in serum and cerebrospinal fluid (CSF) of neuromyelitis optica (NMO) patients, and to analyze the relationship between AQP4 antibody and oligoclonal bands (OB) in CSF
Hui-cong NIU, Xing-hu ZHANG
doaj
Annals of MedicineAquaporin 4 (AQP4) is abundant in the human brain and has an important role in brain homeostasis and diseases. AQP4 expression has been found to be associated with glioma malignancies.
Yu-Long Lan, Shuang Zou, Ruoli Chen
doaj +1 more source
Acta Neuropathologica Communications, 2019 Redistribution of the water channel aquaporin-4 (AQP4) away from astrocyte endfeet and into parenchymal processes is a striking histological feature in mouse models of Alzheimer’s disease (AD) and other neurological conditions with prominent astrogliosis.
Alex J. Smith, Tianjiao Duan, A. Verkman
semanticscholar +1 more source
Expression of aquaporin 1 and aquaporin 4 water channels in rat choroid plexus
Biochimica et Biophysica Acta (BBA) - Biomembranes, 2003 The role of aquaporins in cerebrospinal fluid (CSF) secretion was investigated in this study. Western analysis and immunocytochemistry were used to examine the expression of aquaporin 1 (AQP1) and aquaporin 4 (AQP4) in the rat choroid plexus epithelium.
Speake, Tracey +2 more
openaire +3 more sources
Expression of aquaporin-4 water channels in rat cholangiocytes [PDF]
, 2000 Raúl A. Marinelli +3 more
openalex +1 more source
Acta Neuropathologica Communications, 2019 Cellular injury in AQP4-IgG seropositive neuromyelitis spectrum disorder (herein called NMO) involves AQP4-IgG binding to astrocytes, resulting in astrocyte injury by complement-dependent cytotoxicity (CDC) and antibody-dependent cellular cytotoxicity ...
Tianjiao Duan +2 more
doaj +1 more source
Aquaporin 4 deletion exacerbates brain impairments in a mouse model of chronic sleep disruption
CNS Neuroscience & Therapeutics, 2019 As a normal physiological process, sleep has recently been shown to facilitate clearance of macromolecular metabolic wastes from the brain via the glymphatic system.
Rui Zhang +7 more
semanticscholar +1 more source
Detection and clinical value of NMO-IgG in neuromyelitis optica
Chinese Journal of Contemporary Neurology and Neurosurgery, 2014 Neuromyelitis optica (NMO) is an inflammatory demyelinating disease of the central nervous system (CNS) of autoimmune etiology which predominantly affects the optic nerves and spinal cord.
De-hui HUANG, Wei-ping WU
doaj
Brain : a journal of neurology, 2018 Aquaporin-4 antibodies are pathogenic in neuromyelitis optica spectrum disorders (NMOSD). Wilson et al. show that circulating memory and naïve B cells from patients can differentiate to produce aquaporin-4 antibodies under conditions chosen to mimic ...
Robert Wilson +9 more
semanticscholar +1 more source
The potential roles of aquaporin 4 in malignant gliomas
Oncotarget, 2017 Aquaporin 4 (AQP4) is the major water channel expressed in the central nervous system and is primarily expressed in astrocytes. Recently, accumulated evidence has pointed to AQP4 as a key molecule that could play a critical role in glioma development.
Jia-Cheng Lou +4 more
openaire +4 more sources