Results 1 to 10 of about 38,099 (293)

Aquaporin-6 May Increase the Resistance to Oxidative Stress of Malignant Pleural Mesothelioma Cells [PDF]

open access: yesCells, 2022
Malignant pleural mesothelioma (MPM) is an aggressive cancer of the pleural surface and is associated with previous asbestos exposure. The chemotherapy drug is one of the main treatments, but the median survival ranges from 8 to 14 months from diagnosis.
Giorgia Pellavio   +4 more
doaj   +7 more sources

A region within the third extracellular loop of rat Aquaporin 6 precludes trafficking to plasma membrane in a heterologous cell line [PDF]

open access: yesScientific Reports, 2021
The inability to over-express Aquaporin 6 (AQP6) in the plasma membrane of heterologous cells has hampered efforts to further characterize the function of this aquaglyceroporin membrane protein at atomic detail using crystallographic approaches. Using an
D. C. Soler   +7 more
doaj   +5 more sources

Molecular mechanism of anion permeation through aquaporin 6. [PDF]

open access: yesBiophys J
Aquaporins (AQPs) are recognized as transmembrane water channels that facilitate selective water permeation through their monomeric pores. Among the AQP family, AQP6 has a unique characteristic as an anion channel, which is allosterically controlled by pH conditions and is eliminated by a single amino acid mutation.
Yamamoto E   +4 more
europepmc   +5 more sources

Expression of Aquaporin-6 in Rat Retinal Ganglion Cells. [PDF]

open access: yesCell Mol Neurobiol, 2016
Several aquaporins (AQPs) have been identified to be present in the eyes, and it has been suggested that they are involved in the movement of water and small solutes. AQP6, which has low water permeability and transports mainly anions, was recently discovered in the eyes.
Jang SY, Lee ES, Ohn YH, Park TK.
europepmc   +3 more sources

Decreased Aquaporin 4 and 6 mRNAs in Patients With Chronic Otitis Media With Otorrhea [PDF]

open access: yesClinical and Experimental Otorhinolaryngology, 2019
Objectives Aquaporins (AQPs) are integral membrane proteins engaged in the modulation of water homeostasis, but the roles they play in chronic otitis media (COM) have not been well investigated.
Ji Hoon Kim   +5 more
doaj   +4 more sources

Genome-Wide Characterization of the Aquaporin Gene Family in Radish and Functional Analysis of RsPIP2-6 Involved in Salt Stress

open access: yesFrontiers in Plant Science, 2022
Aquaporins (AQPs) constitute a highly diverse family of channel proteins that transport water and neutral solutes. AQPs play crucial roles in plant development and stress responses.
Xiaofang Yi   +8 more
doaj   +3 more sources

Understanding the relationship between lung GABAA receptors and aquaporin-1: a new therapeutic approach for acute lung injury [PDF]

open access: yesBMC Pulmonary Medicine
Background This study aimed to investigate the effects of the GABAA receptor and the potential relationship between GABA/ GABAA receptor signalling and aquaporin-1 in acute lung injury (ALI).
Hamza Halici   +5 more
doaj   +2 more sources

Synovial Fluid of Patient With Rheumatoid Arthritis Enhanced Osmotic Sensitivity Through the Cytotoxic Edema Module in Synoviocytes

open access: yesFrontiers in Cell and Developmental Biology, 2021
Rheumatoid arthritis (RA) is an autoimmune disease that causes inflammation of the synovial membrane ultimately leading to permanent damage in the affected joints.
Min Jeong Ji   +3 more
doaj   +1 more source

Vascular Inflammation Is Associated with Loss of Aquaporin 1 Expression on Endothelial Cells and Increased Fluid Leakage in SARS-CoV-2 Infected Golden Syrian Hamsters

open access: yesViruses, 2021
Vascular changes represent a characteristic feature of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection leading to a breakdown of the vascular barrier and subsequent edema formation.
Lisa Allnoch   +12 more
doaj   +1 more source

IDENTIFICATION OF AQUAPORIN 7 GENE POLYMORPHISM AND IN-VIVO FERTILITY OF EGYPTIAN BUFFALO BULLS [PDF]

open access: yesSPERMOVA, 2021
This work aimed to investigate the genetic polymorphism of Aquaporin 7 (AQP7) gene and its association with the in-vivo fertility of Egyptian buffalo bulls. A total of 188 fresh semen ejaculates were collected from 47 buffalo bulls and subjected to semen
Mahmoud Hasanain   +5 more
doaj   +1 more source

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