Results 1 to 10 of about 36,778 (260)

Aquaporin-6 May Increase the Resistance to Oxidative Stress of Malignant Pleural Mesothelioma Cells. [PDF]

Cells, 2022
Malignant pleural mesothelioma (MPM) is an aggressive cancer of the pleural surface and is associated with previous asbestos exposure. The chemotherapy drug is one of the main treatments, but the median survival ranges from 8 to 14 months from diagnosis.
Pellavio G, Martinotti S, Patrone M, Ranzato E, Laforenza U.   +4 more
europepmc   +6 more sources

A region within the third extracellular loop of rat Aquaporin 6 precludes trafficking to plasma membrane in a heterologous cell line. [PDF]

Sci Rep, 2021
The inability to over-express Aquaporin 6 (AQP6) in the plasma membrane of heterologous cells has hampered efforts to further characterize the function of this aquaglyceroporin membrane protein at atomic detail using crystallographic approaches. Using an
Soler DC, Kowatz T, Sloan AE, McCormick TS, Cooper KD, Stepanyan R, Engel A, Vahedi-Faridi A.   +7 more
europepmc   +5 more sources

Expression of Aquaporin-6 in Rat Retinal Ganglion Cells. [PDF]

Cell Mol Neurobiol, 2016
Several aquaporins (AQPs) have been identified to be present in the eyes, and it has been suggested that they are involved in the movement of water and small solutes. AQP6, which has low water permeability and transports mainly anions, was recently discovered in the eyes.
Jang SY, Lee ES, Ohn YH, Park TK.
europepmc   +3 more sources

Molecular mechanism of anion permeation through aquaporin 6. [PDF]

Biophys J
Aquaporins (AQPs) are recognized as transmembrane water channels that facilitate selective water permeation through their monomeric pores. Among the AQP family, AQP6 has a unique characteristic as an anion channel, which is allosterically controlled by pH conditions and is eliminated by a single amino acid mutation.
Yamamoto E, Joo K, Lee J, Sansom MSP, Yasui M.   +4 more
europepmc   +5 more sources

Decreased Aquaporin 4 and 6 mRNAs in Patients With Chronic Otitis Media With Otorrhea [PDF]

Clinical and Experimental Otorhinolaryngology, 2019
Objectives Aquaporins (AQPs) are integral membrane proteins engaged in the modulation of water homeostasis, but the roles they play in chronic otitis media (COM) have not been well investigated.
Ji Hoon Kim, Sung Su Kim, Young Il Kim, Su Young Jung, Sang Hoon Kim, Seung Geun Yeo   +5 more
doaj   +4 more sources

Genome-Wide Characterization of the Aquaporin Gene Family in Radish and Functional Analysis of RsPIP2-6 Involved in Salt Stress

Frontiers in Plant Science, 2022
Aquaporins (AQPs) constitute a highly diverse family of channel proteins that transport water and neutral solutes. AQPs play crucial roles in plant development and stress responses.
Xiaofang Yi, Xiaochuan Sun, Rong Tian, Kexin Li, Meng Ni, Jiali Ying, Liang Xu, Liwang Liu, Yan Wang   +8 more
doaj   +3 more sources

Understanding the relationship between lung GABA_A receptors and aquaporin-1: a new therapeutic approach for acute lung injury. [PDF]

BMC Pulm Med
Background This study aimed to investigate the effects of the GABAA receptor and the potential relationship between GABA/ GABAA receptor signalling and aquaporin-1 in acute lung injury (ALI).
Halici H, Karakoy Z, Cadirci E, Halici Z, Ozdemir B, Toktay E.   +5 more
europepmc   +2 more sources

Synovial Fluid of Patient With Rheumatoid Arthritis Enhanced Osmotic Sensitivity Through the Cytotoxic Edema Module in Synoviocytes

Frontiers in Cell and Developmental Biology, 2021
Rheumatoid arthritis (RA) is an autoimmune disease that causes inflammation of the synovial membrane ultimately leading to permanent damage in the affected joints.
Min Jeong Ji, Min Jeong Ji, Hee Jung Ryu, Jeong Hee Hong   +3 more
doaj   +1 more source

Vascular Inflammation Is Associated with Loss of Aquaporin 1 Expression on Endothelial Cells and Increased Fluid Leakage in SARS-CoV-2 Infected Golden Syrian Hamsters

Viruses, 2021
Vascular changes represent a characteristic feature of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection leading to a breakdown of the vascular barrier and subsequent edema formation.
Lisa Allnoch, Georg Beythien, Eva Leitzen, Kathrin Becker, Franz-Josef Kaup, Stephanie Stanelle-Bertram, Berfin Schaumburg, Nancy Mounogou Kouassi, Sebastian Beck, Martin Zickler, Vanessa Herder, Gülsah Gabriel, Wolfgang Baumgärtner   +12 more
doaj   +1 more source

Aquaporins 6-12 in the human eye [PDF]

Acta Ophthalmologica, 2012
Aquaporins (AQPs) are widely expressed and have diverse distribution patterns in the eye. AQPs 0-5 have been localized at the cellular level in human eyes. We investigated the presence of the more recently discovered AQPs 6-12 in the human eye.RT-PCR was performed on fresh tissue from two human eyes divided into the cornea, corneal limbus, ciliary body
Tran, Thuy Linh, Bek, Toke, Holm, Lars, la Cour, Morten, Nielsen, Søren, Prause, Jan Ulrik, Rojek, Aleksandra, Hamann, Steffen, Heegaard, Steffen   +8 more
openaire   +4 more sources