Results 111 to 120 of about 197,034 (346)

SWATH Differential Abundance Proteomics and Cellular Assays Show In Vitro Anticancer Activity of Arachidonic Acid- and Docosahexaenoic Acid-Based Monoacylglycerols in HT-29 Colorectal Cancer Cells [PDF]

, 2019
Colorectal cancer (CRC) is one of the most common and mortal types of cancer. There is increasing evidence that some polyunsaturated fatty acids (PUFAs) exercise specific inhibitory actions on cancer cells through different mechanisms, as a previous ...
Fabrikov, Dmitri, González Fernández, María José, Guil Guerrero, José Luis, Ortea, Ignacio, Ramos Bueno, Rebeca Pilar   +4 more
core   +1 more source

Valorization of fishing industry by‐products for biodiesel production: Unlocking the potential of residual fish oil

Biofuels, Bioproducts and Biorefining, EarlyView.
Abstract Fishing waste and its by‐products, whether naturally occurring or generated by the processing industry, represent a significant opportunity for producing high‐value products. These often discarded or underutilized residues can be converted into various valuable products through advanced processing technologies. Among the potential products are
Patrick da Silva Sousa, Francisco Simão Neto, Paulo Gonçalves de Sousa Junior, Francisco Izaias da Silva Aires, Calebe da Rocha Silva, Kaiany Moreira dos Santos, Viviane de Castro Bizerra, Maria Alexsandra Sousa Rios, José Cleiton Sousa dos Santos   +8 more
wiley   +1 more source

17β Estradiol Modulates Perfusion Pressure and Expression of 5-LOX and CYP450 4A in the Isolated Kidney of Metabolic Syndrome Female Rats

International Journal of Endocrinology, 2015
Prevalence of metabolic syndrome and progression of nephropathy depend on sex. We examined a protective effect of estradiol against nephropathy in metabolic syndrome through the modulation of the arachidonic acid metabolism by activating the 5 ...
A. M. Zúñiga-Muñoz, V. Guarner Lans, E. Soria-Castro, E. Diaz-Diaz, R. Torrico-Lavayen, E. Tena-Betancourt, I. Pérez-Torres   +6 more
doaj   +1 more source

Eicosapentaenoic acid and prostacyclin production by cultured human endothelial cells.

Journal of Lipid Research, 1983
Human umbilical vein endothelial cells incorporate eicosapentaenoic acid (EPA) when this fatty acid is present in the culture medium. From 30 to 70% of the uptake remains as EPA, and much of the remainder is elongated to docosapentaenoic acid. All of the
A A Spector, T L Kaduce, P H Figard, K C Norton, J C Hoak, R L Czervionke   +5 more
doaj   +1 more source

Renal tubular arachidonic acid metabolism

Kidney International, 1991
Arachidonic acid and its metabolites play important roles in renal tubular function. This overview will review general characteristics of arachidonic acid metabolism, focus on the characterization and regulation of renal acylhydrolases that generate arachidonic acid from phospholipids, examine what is known about the production of arachidonic acid ...
Bonventre, Joseph V., Nemenoff, Raphael
openaire   +2 more sources

Arachidonic acid, a clinically adverse mediator in the ovarian cancer microenvironment, impairs JAK‐STAT signaling in macrophages by perturbing lipid raft structures

, 2022
Mohamad K. Hammoud, Raimund Dietze, Jelena Pesek, Florian Finkernagel, Annika Unger, Tim Bieringer, Andrea Nist, Thorsten Stiewe, Aditya Bhagwat, Wolfgang Andreas Nockher, Silke Reinartz, Sabine Müller‐Brüsselbach, Johannes Graumann, Rolf Müller   +13 more
openalex   +1 more source

Deciphering the catalytic and pharmacological mechanisms of Coptis chinensis herbzymes to renovate intestinal microenvironment for colitis alleviation

BMEMat, EarlyView.
The synthesized CCzymes possess both antioxidant enzyme activity and pharmacological properties inherent to Coptis chinensis. By their antioxidant enzyme activity, CCzymes can attenuate oxidative stress within the inflammatory region of ulcerative colitis (UC), while their pharmacological activity acts on macrophage polarization and the intestinal ...
Zhichao Deng, Can Li, Yujie Zhang, Yuanyuan Zhu, Chenxi Xu, Bowen Gao, Mingxin Zhang, Martina H. Stenzel, Kelong Fan, Mingzhen Zhang, Yanyan Jiang   +10 more
wiley   +1 more source

Effect of fatty acid saturation on NADPH-dependent lipid peroxidation in rat liver microsomes.

Journal of Lipid Research, 1981
NADPH-dependent lipid peroxidation in liver microsomes, as measured by malondialdehyde formation, decreased by 90% when rats were fed a diet containing 16% coconut oil.
B R Lokesh, S N Mathur, A A Spector
doaj   +1 more source

Nano‐networks via reaction‐induced self‐assembly coordinate spatiotemporal multi‐drug delivery for acute kidney injury therapy

BMEMat, EarlyView.
Multifunctional nano‐networks (NNWs) are prepared via reaction‐induced self‐assembly (RISA) of spermidine (SPD), epigallocatechin gallate (EGCG), 2‐formylphenylboronic acid (2‐FPBA), and deferoxamine (DFO) through dynamic iminoboronate bonds. These NNWs leverage the oxidative AKI microenvironment to trigger disintegration, enabling site‐specific ...
Juan Jin, Xiao Zhang, Chenxi Wang, Taian Jin, Xinyang Fang, Yixuan Gao, Mengchun Chen, Weiyang Meng, Chang Gao, Wenlu Li, Yuanfeng Li, Yijie Chen, Calvin A. Omolo, Thirumala Govender, Linqi Shi, Yunguang Wang, Yong Liu, Qiang He   +17 more
wiley   +1 more source

The chemistry of arachidonic acid oxygenation by prostaglandin endoperoxide synthase

Redox Biochemistry and Chemistry
Prostaglandins are an important class of bioactive lipids derived from arachidonic acid. The different classes of prostaglandins are produced from a common intermediate, called prostaglandin H2.
Lawrence J. Marnett
doaj   +1 more source