Results 181 to 190 of about 189,223 (341)

Biallelic ELOVL1 Variants Are Linked to Hypomyelinating Leukodystrophy, Movement Disorder, and Ichthyosis

Movement Disorders, EarlyView.
Abstract Background Very long chain fatty acids (VLCFAs) are an integral component of myelin and the epidermal water barrier. Variants in genes encoding enzymes responsible for catalyzing the first and rate limiting step in the production of VLCFAs, elongation of VLCFAs (ELOVLs), underlie a novel group of metabolic disorders. Objectives The goal was to
Keit Men Wong, Reza Maroofian, Kolja Meier, Susann Diegmann, Tinatin Tkemaladze, Javeria Raza Alvi, Behnoosh Tasharrofi, Stephanie Efthymiou, Alexander Munchau, G. Christoph Korenke, Naif Almontashiri, Wafaa Eyaid, Amna Kashgari, Modhi Alotaibi, Jutta Gärtner, Brenda Huppke, Mostafa Asadollahi, Gocha Chikvinidze, Mohammad Keramatipour, Tipu Sultan, Holger Thiele, Peter Nürnberg, Markus H. Gräler, Henry Houlden, Peter Huppke   +24 more
wiley   +1 more source

Dysregulation of Arachidonic Acid Metabolism Drives Inflammatory Lipid Production in Localized Provoked Vulvodynia. [PDF]

Nutrients
Fischer SA, Oladele O, Mahamed Z, Chrysilla E, Baumer A, Bekauri T, Maddipati KR, Love T, Linder M, Falsetta M.   +9 more
europepmc   +1 more source

Molecular Tools to Study and Control Dopaminergic Neurotransmission With Light

Medicinal Research Reviews, EarlyView.
ABSTRACT Dopaminergic neurotransmission is involved in several important brain functions, such as motor control, learning, reward‐motivated behavior, and emotions. Dysfunctions of dopaminergic system may lead to the development of various neurological and psychiatric disorders, like Parkinson's disease, schizophrenia, depression, and addictions ...
Galyna Maleeva, Carlo Matera, Silvia Roda, Alessio Colleoni, Marco De Amici, Pau Gorostiza   +5 more
wiley   +1 more source

Fecal Arachidonic Acid: A Potential Biomarker for Inflammatory Bowel Disease Severity. [PDF]

Int J Mol Sci
Huss M, Elger T, Kunst C, Loibl J, Krautbauer S, Liebisch G, Kandulski A, Müller M, Tews HC, Buechler C.   +9 more
europepmc   +1 more source

Arachidonic acid synthesis studied in isolated liver cells [PDF]

, 1981
Bjørn O. Christophersen, Jon Norseth
openalex   +1 more source

Benefits of Krill Oil Supplementation During Alternate‐Day Fasting in Adults With Overweight and Obesity: A Randomized Trial

Obesity, EarlyView.
ABSTRACT Objective To investigate the effect of krill oil (KO) supplementation during alternate‐day fasting (ADF) on body composition and muscle function in healthy adults with overweight. Methods In a randomized trial, during the 8‐week ADF, participants consumed four capsules per day containing krill oil (KO group) or vegetable oil (placebo group ...
Mansour Alblaji, Stuart R. Gray, Taibah Almesbehi, Douglas J. Morrison, Dalia Malkova   +4 more
wiley   +1 more source

Androgen receptor promotes arachidonic acid metabolism and angiogenic microenvironment in AFP-negative hepatocellular carcinoma. [PDF]

Nat Commun
Lin Z, Liu X, Wang H, Li S, Miao Z, Yang J, Zhang Y, Lei K, Wu Y, Kang Y, Zheng R, Xie Z, Wen Y, Ren X, Liu C, Cheng AS, Xie Y, Chen S, Kuang M, Peng S, Peng Z, Dai Z.   +21 more
europepmc   +1 more source

Nrf2‐Mediated Ferroptosis Is Involved in Berberine‐Induced Alleviation of Diabetic Kidney Disease

Phytotherapy Research, EarlyView.
ABSTRACT Diabetic kidney disease (DKD) is the most common and serious complication of diabetes mellitus. Currently, there is a lack of safe and effective preventive strategies for DKD. The study aimed to explore the preventive effects and potential mechanisms of berberine (BBR) against DKD.
Kun Gao, Yunhua Liu, Kun Li, Lin Liu, Yanmo Cai, Xinxue Zhang, Zongjiang Zhao   +6 more
wiley   +1 more source

Dietary Gluten-Free Regimen Does Not Affect the Suppression of the Inflammatory Response in the Arachidonic Acid Cascade in Hashimoto's Disease. [PDF]

Int J Mol Sci
Szczuko M, Kwiatkowska L, Szczuko U, Rudak L, Ryterska K, Syrenicz A, Pobłocki J, Drozd A.   +7 more
europepmc   +1 more source

Astrocyte Lipid Droplet Dynamics Orchestrate Neurological Disorders and Therapeutic Horizons

Small Science, EarlyView.
This review examines astrocyte lipid droplet (LD) metabolism in neurological disorders, including Alzheimer's disease, stroke, epilepsy, and glioma. It analyzes regulatory mechanisms governing LD formation, transport, and degradation in astrocytes, highlighting their potential as biomarkers and therapeutic targets through integrative multiomics ...
Jiani Zhong, Yanyi Peng, Lingyue Zhang, Bo Xiao, Mengqi Zhang   +4 more
wiley   +1 more source