Results 31 to 40 of about 197,034 (346)
Nature Communications, 2023 Colonocyte metabolism shapes the microbiome. Metabolites are the main mediators of information exchange between intestine and microbial communities. Arachidonic acid (AA) is an essential polyunsaturated fatty acid and its role in colorectal cancer (CRC ...
Chunjie Xu +12 more
doaj +1 more source
5 S,15 S-Dihydroperoxyeicosatetraenoic Acid (5,15-diHpETE) as a Lipoxin Intermediate: Reactivity and Kinetics with Human Leukocyte 5-Lipoxygenase, Platelet 12-Lipoxygenase, and Reticulocyte 15-Lipoxygenase-1. [PDF]
, 2018 The reaction of 5 S,15 S-dihydroperoxyeicosatetraenoic acid (5,15-diHpETE) with human 5-lipoxygenase (LOX), human platelet 12-LOX, and human reticulocyte 15-LOX-1 was investigated to determine the reactivity and relative rates of producing lipoxins (LXs).
Freedman, Cody +6 more
core +3 more sources
Journal of Lipid Research, 2000 The demonstration of in vivo arachidonic acid epoxidation and ω-hydroxylation established the cytochrome P450 epoxygenase and ω/ω–1 hydroxylase as formal metabolic pathways and as members of the arachidonate metabolic cascade. The characterization of the
Jorge H. Capdevila +2 more
doaj +1 more source
Hydrocortisone inhibits prostaglandin production but not arachidonic acid release from cultured macrophages [PDF]
, 1984 We have investigated the action of hydrocortisosone on arachidonic acid mobilisation in cultures of mouse peritoneal macrophages, mouse L929 cells and the mouse macrophage-like cell line RAW264.
Clancy +16 more
core +5 more sources
Journal of Lipid Research, 1979 A gas-liquid chromatography-flame ionization method is described for measuring arachidonic acid in plasma using dihomo-gamma-linolenic acid as an internal standard.
J G Gerber, J S Barnes, A S Nies
doaj +1 more source
Polyunsaturated fatty acids in the pathogenesis and treatment of multiple sclerosis [PDF]
, 2007 Epidemiological, biochemical, animal model and clinical trial data described in this overview strongly suggest that polyunsaturated fatty acids, particularly n-6 fatty acids, have a role in the pathogenesis and treatment of multiple sclerosis (MS).
Copeland +16 more
core +2 more sources
Dietary arachidonic acid: a Janus face actor in brain and Alzheimer’s disease?
Oilseeds and fats, crops and lipids, 2018 Arachidonic acid is the second polyunsaturated fatty acid in brain and the first one belonging to the ω-6 series. Dietary intakes of arachidonic are between 50 and 300 mg/day in western diets but they might be underestimated. Triglycerides from fat would
Pinchaud Katleen +2 more
doaj +1 more source
Modulation of guanosine triphosphatase activity of G proteins by arachidonic acid in rat Leydig cell membranes [PDF]
, 2000 Previous results from our group have indicated that arachidonic acid decrease cAMP production through a modification of heterotrimericGproteins.\ud In the present study, we have characterized the high affinity GTPase activity present in Leydig cell ...
Colás Escudero, Begoña +4 more
core +3 more sources
Effect of fatty acid modification on prostaglandin production by cultured 3T3 cells.
Journal of Lipid Research, 1982 We have investigated the extent to which modifications in the essential fatty acid content of mammalian cells can affect prostaglandin production.
G M Denning, P H Figard, A A Spector
doaj +1 more source
Advanced Healthcare Materials, EarlyView.Human iPSC‐derived hypertrophic chondrocyte sheet promotes bone regeneration. Abstract Bone defects are a major clinical challenge, primarily owing to the limited self‐healing capacity of bones and the high risk of complications associated with conventional treatment strategies.
Yiwei Chen +9 more
wiley +1 more source