Results 31 to 40 of about 194,523 (350)
Journal of Lipid Research, 2000 The demonstration of in vivo arachidonic acid epoxidation and ω-hydroxylation established the cytochrome P450 epoxygenase and ω/ω–1 hydroxylase as formal metabolic pathways and as members of the arachidonate metabolic cascade. The characterization of the
Jorge H. Capdevila +2 more
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Nature Communications, 2023 Colonocyte metabolism shapes the microbiome. Metabolites are the main mediators of information exchange between intestine and microbial communities. Arachidonic acid (AA) is an essential polyunsaturated fatty acid and its role in colorectal cancer (CRC ...
Chunjie Xu +12 more
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Modulation of guanosine triphosphatase activity of G proteins by arachidonic acid in rat Leydig cell membranes [PDF]
, 2000 Previous results from our group have indicated that arachidonic acid decrease cAMP production through a modification of heterotrimericGproteins.\ud In the present study, we have characterized the high affinity GTPase activity present in Leydig cell ...
Colás Escudero, Begoña +4 more
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Journal of Lipid Research, 1979 A gas-liquid chromatography-flame ionization method is described for measuring arachidonic acid in plasma using dihomo-gamma-linolenic acid as an internal standard.
J G Gerber, J S Barnes, A S Nies
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Probing the Electrostatic and Steric Requirements for Substrate Binding in Human Platelet-Type 12-Lipoxygenase. [PDF]
, 2019 Human platelet ALOX12 (hALOX12 or h12-LOX) has been implicated in a variety of human diseases. The present study investigates the active site of hALOX12 to more thoroughly understand how it positions the substrate and achieves nearly perfect regio- and ...
Aleem, Ansari Mukhtar +7 more
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Dietary arachidonic acid: a Janus face actor in brain and Alzheimer’s disease?
Oilseeds and fats, crops and lipids, 2018 Arachidonic acid is the second polyunsaturated fatty acid in brain and the first one belonging to the ω-6 series. Dietary intakes of arachidonic are between 50 and 300 mg/day in western diets but they might be underestimated. Triglycerides from fat would
Pinchaud Katleen +2 more
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Arachidonic Acid in Human Milk [PDF]
Nutrients, 2020 Breastfeeding is universally recommended as the optimal choice of infant feeding and consequently human milk has been extensively investigated to unravel its unique nutrient profile. The human milk lipid composition is unique and supplies specifically long-chain polyunsaturated fatty acids (LC-PUFAs), in particular, arachidonic acid (ARA, 20:4n–6) and ...
Salem, Norman, Van Dael, Peter
openaire +2 more sources
Effect of fatty acid modification on prostaglandin production by cultured 3T3 cells.
Journal of Lipid Research, 1982 We have investigated the extent to which modifications in the essential fatty acid content of mammalian cells can affect prostaglandin production.
G M Denning, P H Figard, A A Spector
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Hydrophobic Ligand Binding by Zn-α_2-glycoprotein, a Soluble Fat-depleting Factor Related to Major Histocompatibility Complex Proteins [PDF]
, 2001 Zn-alpha2-glycoprotein (ZAG) is a member of the major histocompatibility complex (MHC) class I family of proteins and is identical in amino acid sequence to a tumor-derived lipid-mobilizing factor associated with cachexia in cancer patients.
Bjorkman, Pamela J. +4 more
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FADS Gene Cluster Polymorphisms: Important Modulators of Fatty Acid Levels and Their Impact on Atopic Diseases [PDF]
, 2009 Long-chain polyunsaturated fatty acids (LC-PUFAs) play an important role in several physiological processes and their concentration in phospholipids has been associated with several complex diseases, such as atopic disease.
Heinrich, Joachim +3 more
core +1 more source