Results 61 to 70 of about 2,614,074 (305)
Advanced Science, EarlyView.Resolution pharmacology is an emerging strategy to tackle inflammatory pathologies. Bioinspired meroterpenoids induce a lipid mediator class switch toward inflammation resolution in vitro and in vivo by targeting key nodes in lipid mediator biosynthesis and neutral lipid dynamics.
Lorenz Waltl +20 more
wiley +1 more source
BMC Cancer, 2004 Background Tamoxifen is being used successfully to treat breast cancer. However, tamoxifen also increases the risk of developing endometrial cancer in postmenopausal women.
Levine Lawrence
doaj +1 more source
, 2012 : Sepsis-associated changes of the arachidonic acid metabolism and the utility of arachidonic acid metabolites for the diagnosis of sepsis have been poorly investigated so far.
Bruegel, Mathias +8 more
core +1 more source
A multiscale hybrid model for pro-angiogenic calcium signals in a vascular endothelial cell [PDF]
, 2011 Cytosolic calcium machinery is one of the principal signaling mechanisms by which endothelial cells (ECs) respond to external stimuli during several biological processes, including vascular progression in both physiological and pathological conditions ...
Marco Scianna, Scianna, Marco
core +1 more source
Advanced Science, EarlyView.Magneto‐NIR‐II‐programmed NFSH nanozymes integrate magnetic blood–brain barrier (BBB) translocation, CD44 targeting, multimodal imaging, and cascade catalytic therapy for glioblastoma. Alternating magnetic fields and NIR‐II irradiation amplify ferroptosis, release H2S, suppress autophagic and mitophagic repair, and reshape the immune microenvironment ...
Ruocan Liu +7 more
wiley +1 more source
LDL fatty acids composition as a risk biomarker of cardiovascular disease
Artery Research, 2017 Objective: Fatty acid composition of Low-density lipoprotein (LDL) particle is an effective factor in LDL oxidation and atherosclerotic plaques formation.
Hashem Nayeri +6 more
doaj +1 more source
Arachidonic Acid Production by Fungi [PDF]
Applied and Environmental Microbiology, 1991 After preliminary screening, Mortierella alpina and Mortierella elongata were compared with respect to arachidonic acid content. M. alpina ATCC 16266 produced 2.1 g of arachidonic acid per liter in media containing 10% glucose while the highest percentage of ...
P K, Bajpai, P, Bajpai, O P, Ward
openaire +2 more sources
Advanced Science, EarlyView.LDHA‐driven lactate production in mesenchymal glioma stem cells promotes p300‐dependent H3K18 lactylation, activates USP30 transcription, and stabilizes MBOAT2 to remodel phosphatidylethanolamines toward ferroptosis‐resistant PE‐MUFA species. Disrupting this metabolic–epigenetic–lipid circuit enhances ferroptosis and sensitizes glioblastoma to ...
Zong Miao +13 more
wiley +1 more source
Arachidonic acid as a bioactive molecule [PDF]
Journal of Clinical Investigation, 2001 Arachidonic acid is a slippery molecule that owes its mobility to its four cis double bonds. These are the source of its flexibility, keeping the pure fatty acid liquid, even at subzero temperatures, and helping to give mammalian cell membranes their correct fluidity at physiological temperatures.
openaire +2 more sources
Wing (Ib) cells in frog taste discs detect dietary unsaturated fatty acids [PDF]
, 2013 The effects of unsaturated fatty acids on membrane properties were studied using conventional whole-cell patch-clamp recording of isolated wing (Ib) cells in bullfrog (Lithobates catesbeianus) taste discs.
Miyazaki, Toshihiro +3 more
core +1 more source