Results 31 to 40 of about 5,079,671 (304)

Arachidonic acid in cell signaling [PDF]

Current Opinion in Cell Biology, 1993
Important advances have recently been made in our understanding of the arachidonic acid cascade. The molecular characterization of different forms of phospholipase A2 indicates that multiple pathways are involved in the release of arachidonic acid evoked by physiological or pathological stimuli.
openaire   +4 more sources

Polyunsaturated fatty acids in the pathogenesis and treatment of multiple sclerosis [PDF]

, 2007
Epidemiological, biochemical, animal model and clinical trial data described in this overview strongly suggest that polyunsaturated fatty acids, particularly n-6 fatty acids, have a role in the pathogenesis and treatment of multiple sclerosis (MS).
Copeland, Esparza, Fitzgerald, Harbige, Harbige, Jones, Karpus, Laurence S. Harbige, Mohammad K. Sharief, Mokhtarian, Ovadia, Santambrogio, Selmaj, Serafina, Thompson, Thompson, Vartanian   +16 more
core   +2 more sources

Factors affecting the elicitation of sesquiterpenoid phytoalexin accumulation by eicosapentaenoic and arachidonic acids in potato.

Plant Physiology, 1982
Eicosapentaenoic and arachidonic acids in extracts of Phytophthora infestans mycelium were identified as the most active elicitors of sesquiterpenoid phytoalexin accumulation in potato tuber slices.
R. Bostock, Roger A. Laine, Joseph Kuć
semanticscholar   +1 more source

Probing the Electrostatic and Steric Requirements for Substrate Binding in Human Platelet-Type 12-Lipoxygenase. [PDF]

, 2019
Human platelet ALOX12 (hALOX12 or h12-LOX) has been implicated in a variety of human diseases. The present study investigates the active site of hALOX12 to more thoroughly understand how it positions the substrate and achieves nearly perfect regio- and ...
Aleem, Ansari Mukhtar, Alvarez, Gabriella, Deschamps, Joshua, Holman, Theodore, Jacobson, Matthew P, Kalyanaraman, Chakrapani, Tena, Jennyfer, Tsai, Wan-Chen   +7 more
core   +2 more sources

LDL fatty acids composition as a risk biomarker of cardiovascular disease

Artery Research, 2017
Objective: Fatty acid composition of Low-density lipoprotein (LDL) particle is an effective factor in LDL oxidation and atherosclerotic plaques formation.
Hashem Nayeri, Gholam Ali Naderi, Sedigheh Asgari, Masoumeh Sadeghi, Maryam Boshtam, Samaneh Mohamadzadeh, Nasim Babaknejad   +6 more
doaj   +1 more source

Nitrogen dioxide induces cis-trans-isomerization of arachidonic acid within cellular phospholipids. Detection of trans-arachidonic acids in vivo.

Journal of Biological Chemistry, 1999
Oxygen free radicals oxidize arachidonic acid to a complex mixture of metabolites termed isoeicosanoids that share structural similarity to enzymatically derived eicosanoids.
H. Jiang, N. Kruger, D. R. Lahiri, D. Wang, J. Vatele, M. Balazy   +5 more
semanticscholar   +1 more source

Three-year tracking of fatty acid composition of plasma phospholipids in healthy children [PDF]

, 2007
Objectives: The fatty acid composition of plasma phospholipids reflects the dietary fatty acid intake as well as endogenous turnover. We aimed at investigating the potential tracking of plasma phospholipid fatty acid composition in children that ...
Andersson A, André Michael Toschke, António Guerra, Baylin A, Baylin A, Berenson GS, Berthold Koletzko, Decsi T, Demmelmair H, Di Stasi D, Folch J, Frank GC, Hamill PV, Hans Demmelmair, Katan MB, Koletzko B, Koletzko B, Kwiterovich, Lee J, Lenfant C, Livingstone MB, Luukkainen P, Ma J, Miettinen TA, Moilanen T, Moilanen T, National Cholesterol Education Program, Ntambi JM, Riboli E, Rockett HR, Schaeffer L, Sellmayer A, Serdula MK, Svensson BG, Vobecky JS, Zeleniuch-Jacquotte A   +35 more
core   +1 more source

Dietary N-3 polyunsaturated fatty acids decrease biliary cholesterol saturation in gallstone disease [PDF]

, 1992
Because fatty acid composition of biliary phospholipids influences cholesterol secretion into bile, we investigated whether replacement of n-1 monounsaturated or n-6 polyunsaturated fatty acids with n-3 polyunsaturated fatty acids in biliary ...
Abell, Ahlberg, Balasubramaniam, Barlett, Bernd Seifferth, Berr, Berr, Berr, Berr, Carey, Carey, Carulli, Cohen, Cohen, Coleman, Dam, Delchier, Dieter Jüngst, Everson, Frieder Berr, Glenn, Goodnight, Gustav Paumgartner, Harris, Hofmann, Holan, Holzbach, Joseph Holl, Juniper, Kaludzny, Kelly, Kuroki, Leaf, Lee, Lippel, Lorenz, Magnuson, Marks, Nestel, Nestel, O'Leary, Parhofer, Paul, Phillipson, Pomeranz, Ramond, Robins, Robins, Sanders, Scobey, Sedaghat, Snedecor, Strasberg, Sven Fischer, Sömjen, Ventura, von Schacky, Wagner, Wechsler, Werner O. Richter   +59 more
core   +1 more source

Mast Cells, Astrocytes, Arachidonic Acid: Do They Play a Role in Depression?

Applied Sciences, 2020
Evidence support that brain membrane fatty acids play a crucial role in psychopathologies such as depression and anxiety disorders. Although the pathogenesis of depression is not still defined, drugs commonly used to reduce arachidonic turnover in the ...
Giovanna Traina, Massimo Cocchi
doaj   +1 more source

Metabolic disorder and intestinal microflora dysbiosis in chronic inflammatory demyelinating polyradiculoneuropathy

Cell & Bioscience, 2023
Objective Chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) is a rare acquired immune-mediated neuropathy. Although microbial infection is potentially a contributing factor, a causative link between CIDP and microbial infection remains ...
Jiafang Fu, Jingli Shan, Yazhou Cui, Chuanzhu Yan, Qinzhou Wang, Jinxiang Han, Guangxiang Cao   +6 more
doaj   +1 more source