Results 71 to 80 of about 5,117,744 (378)
Lipids in Health and Disease, 2012 Background Fatty acid-induced insulin resistance and impaired glucose uptake activity in muscle cells are fundamental events in the development of type 2 diabetes and hyperglycemia.
Sawada Keisuke +5 more
doaj +1 more source
New perspective in fisheries product development: importance of seaweeds as biomass resources [PDF]
, 2013 Brown seaweeds have an important role to preserve coastal ecosystems. Brown seaweeds are also major class for aquacultured seaweeds. They contain valuable nutrients and bioactive components and some of them have not been found in terrestrial plants ...
Miyashita, Kazuo
core
Linoleic acid participates in the response to ischemic brain injury through oxidized metabolites that regulate neurotransmission. [PDF]
, 2017 Linoleic acid (LA; 18:2 n-6), the most abundant polyunsaturated fatty acid in the US diet, is a precursor to oxidized metabolites that have unknown roles in the brain.
Bazinet, Richard P +11 more
core +1 more source
Advanced Science, EarlyView.The bottom‐up strategy based on multiomics data is used for the SynCom design, and it successfully inhibited F. nucleatum growth and achieved stable colonization in vivo. In addition, it promoted tryptophan metabolism and secondary bile acid conversion, reduced lipid accumulation, relieved microbiome disorder, decreased inflammatory reaction, and ...
Zhongkun Zhou +11 more
wiley +1 more source
Angewandte Chemie, EarlyView.This study innovatively develops a multifunctional, multienzyme‐active nanoplatform (FeCP@PDA‐GOx), aimed at overcoming the limitations of traditional cancer therapies and achieving precise, efficient, and long‐lasting melanoma treatment. By integrating starvation therapy, CDT, mPTT, and immunotherapy, FeCP@PDA‐GOx generates a multidimensional ...
Qihang Ding +6 more
wiley +2 more sources
Periparturient lipolysis and oxylipid biosynthesis in bovine adipose tissues. [PDF]
PLoS ONE, 2017 The periparturient period of dairy cows is characterized by intense lipolysis in adipose tissues (AT), which induces the release of free fatty acids (FFA) into circulation.
G Andres Contreras +6 more
doaj +1 more source
The metabolomics of psoriatic disease. [PDF]
, 2017 Metabolomics is an emerging new "omics" field involving the systematic analysis of the metabolites in a biologic system. These metabolites provide a molecular snapshot of cellular activity and are thus important for understanding the functional changes ...
Afifi, Ladan +6 more
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Mechanism of NaCl transport-stimulated prostaglandin formation in MDCK cells [PDF]
, 1987 Recently we have found that stimulation of NaCl transport in high-resistance MDCK cells enhances their prostaglandin formation. In the present study, we investigated the mechanisms by which prostaglandin formation could be linked to the ion transport in ...
Bauer, C. +4 more
core +1 more source
Arachidonic acid as a bioactive molecule [PDF]
Journal of Clinical Investigation, 2001 Arachidonic acid is a slippery molecule that owes its mobility to its four cis double bonds. These are the source of its flexibility, keeping the pure fatty acid liquid, even at subzero temperatures, and helping to give mammalian cell membranes their correct fluidity at physiological temperatures.
openaire +3 more sources
Advanced Science, EarlyView.Occlusion of tumor blood vessels represents a promising yet challenging approach in cancer treatment. Herein, supramolecularly engineered platelets conjugated with morphology‐transformable nanoparticles is developed for precise tumor embolization. The engineered platelets actively accumulate at tumor sites following induced blood vessel injury.
Junyan Li +9 more
wiley +1 more source