Results 51 to 60 of about 80,337 (315)
, 2018 Molecular chaperones promote the correct folding of proteins in aggregation-prone cellular environments by stabilizing nascent polypeptide chains and providing appropriate folding conditions. Prefoldins (PFDs) are molecular chaperones found in archaea and eukaryotes, generally characterized by a unique jellyfish-like hexameric structure consisting of a
Lim, S, Glover, DJ, Clark, DS
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A working model for cytoplasmic assembly of H/ACA snoRNPs
FEBS Letters, EarlyView.Dyskerin is the component of nuclear H/ACA ribonucleoproteins (RNPs) endowed with pseudouridine synthase catalytic activity. Two isoforms of human dyskerin have been characterized: the abundant Iso1, mainly nuclear, and the shorter Iso3, mainly cytoplasmic but occasionally imported into nuclei.
Alberto Angrisani, Maria Furia
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At the core of the Archaea. [PDF]
Proceedings of the National Academy of Sciences, 1996 There are three kinds of taxonomists, according to Ernst Mayr (1). Pheneticists group species by overall phenotypic similarity, renouncing evolutionary theory and explanation. Cladists, conversely, concern themselves exclusively with genealogy. Phenotypic resemblance between two taxa (lizards and crocodiles as reptiles, for instance), counts for ...
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Harnessing Next‐Generation 3D Cancer Models to Elucidate Tumor‐Microbiome Crosstalk
Advanced Healthcare Materials, EarlyView.Centralizes the microbiome within 3D tumor‐microbiome model platforms, including spheroids, organoids, 3D‐bioprinted constructs, and microfluidic chips, each enabling structured host‐tumor‐microbe studies. These systems support bacterial colonization, facilitating investigation of microbial impacts on tumor growth, immunity, and therapy. The microbiome
Marina Green Buzhor +12 more
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Current Biology, 1996 There's an old joke that circulates in newsrooms. A reporter rushes up to City Desk and breathlessly tells his editor that he has confirmed the Second Coming of Christ. The editor doesn't want the story. “We had that one already — 2 000 years ago.” If it's news, it has to be the first, the biggest, the oldest or the most, especially in science news. So,
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Archaea, 2007 The gene‐dense chromosomes of archaea and bacteria were long thought to be devoid of pseudogenes, but with the massive increase in available genome sequences, whole genome comparisons between closely related species have identified mutations that have rendered numerous genes inactive.
Christopher Smillie +2 more
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Advanced Materials, EarlyView.This review gives a summary on the representative bioinspired single‐atomic‐site catalysts (SACs) and their applications in heterogeneous electrocatalysis and photocatalysis. The fundamentals of bioinspired design strategies are systematically discussed in the context of the first shell coordination, the second/long‐range coordination, and the outer ...
Ying Wang +4 more
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mBio, 2023 Facing rapid fluctuations in their natural environment, extremophiles, like the hyperthermophilic archaeon Pyrococcus furiosus, exhibit remarkable adaptability to extreme conditions.
Felix Grünberger +9 more
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Probiotic‐Based Materials as Living Therapeutics
Advanced Materials, EarlyView.Recent advances in Engineered Living Materials are highlighted, integrating synthetic biology and advanced materials, with a focus on probiotic‐based therapeutics. Probiotic Living Materials hold great potential for biosensing, infection treatment, osteogenesis, wound healing, vaginal and gastrointestinal disorders, and cancer therapy. breakthroughs in
Laura Sabio +2 more
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Advanced Science, EarlyView.The TIDE‐Cas14a system, an integrated RPA‐T7‐CRISPR/Cas14a cascade platform incorporating engineered crRNA mismatches, enables ultrasensitive detection of the PIK3CA H1047R mutation in breast cancer circulating tumor DNA, with a limit of detection as low as 0.01%, surpassing the sensitivity of droplet digital PCR.
Yuanyuan Yu +19 more
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