How Does the Archaellum Work? [PDF]
BiomoleculesThe archaellum is the simplest known molecular propeller. An analogue of bacterial flagella, archaella are long helical tails found in Archaea that are rotated by cell-envelope-embedded rotary motors to exert thrust for cell motility.
Beeby M, Daum B.
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Towards Elucidating the Rotary Mechanism of the Archaellum Machinery. [PDF]
Front Microbiol, 2022 Motile archaea swim by means of a molecular machine called the archaellum. This structure consists of a filament attached to a membrane-embedded motor.
Nuno de Sousa Machado J +2 more
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How Did the Archaellum Get Its Rotation? [PDF]
Front Microbiol, 2021 How new functions evolve fascinates many evolutionary biologists. Particularly captivating is the evolution of rotation in molecular machines, as it evokes familiar machines that we have made ourselves. The archaellum, an archaeal analog of the bacterial
Ortega D, Beeby M.
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An archaellum filament composed of two alternating subunits. [PDF]
Nat Commun, 2022 The archaellum is a molecular machine used by archaea to swim, consisting of an intracellular motor that drives the rotation of an extracellular filament composed of multiple copies of proteins named archaellins.
Gambelli L +7 more
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Interaction of two strongly divergent archaellins stabilizes the structure of the Halorubrum archaellum [PDF]
MicrobiologyOpen, 2020 Halophilic archaea from the genus Halorubrum possess two extraordinarily diverged archaellin genes, flaB1 and flaB2. To clarify roles for each archaellin, we compared two natural Halorubrum lacusprofundi strains: One of them contains both archaellin ...
Mikhail G. Pyatibratov +10 more
doaj +7 more sources
Perturbed N-glycosylation of Halobacterium salinarum archaellum filaments leads to filament bundling and compromised cell motility. [PDF]
Nat CommunThe swimming device of archaea—the archaellum—presents asparagine (N)-linked glycans. While N-glycosylation serves numerous roles in archaea, including enabling their survival in extreme environments, how this post-translational modification contributes ...
Sofer S +6 more
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Low Salt Influences Archaellum-Based Motility, Glycerol Metabolism, and Gas Vesicles Biogenesis in Halobacterium salinarum. [PDF]
Microorganisms, 2022 Halobacterium salinarum NRC-1 is an extremophile that grows optimally at 4.3 M NaCl concentration. In spite of being an established model microorganism for the archaea domain, direct comparisons between its proteome and transcriptome during osmotic ...
Onga EA, Vêncio RZN, Koide T.
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Evolution of Archaellum Rotation Involved Invention of a Stator Complex by Duplicating and Modifying a Core Component. [PDF]
Front Microbiol, 2021 Novelty in biology can arise from opportunistic repurposing of nascent characteristics of existing features. Understanding how this process happens at the molecular scale, however, suffers from a lack of case studies. The evolutionary emergence of rotary
Umrekar TR +5 more
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Structure and in situ organisation of the Pyrococcus furiosus archaellum machinery
eLife, 2017 The archaellum is the macromolecular machinery that Archaea use for propulsion or surface adhesion, enabling them to proliferate and invade new territories.
Bertram Daum +7 more
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The transcriptional regulator EarA and intergenic terminator sequences modulate archaellation in Pyrococcus furiosus. [PDF]
Front Microbiol, 2023 The regulation of archaellation, the formation of archaeal-specific cell appendages called archaella, is crucial for the motility, adhesion, and survival of archaeal organisms.
Stöckl R +5 more
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