Results 21 to 30 of about 293 (137)
Archaeosome: As New Drug Carrier for Delivery of Paclitaxel to Breast Cancer [PDF]
Indian Journal of Clinical Biochemistry, 2014 In the present study, paclitaxel was archaeosomed to reduce side effects and improve its therapeutic index. Carriers have made a big evolution in treatment of many diseases in recent years. Lipid carriers are of special importance among carriers. Archaeosome is one of the lipid carriers.
Mohsen Chiani +2 more
exaly +8 more sources
RD antigen based nanovaccine imparts long term protection by inducing memory response against experimental murine tuberculosis. [PDF]
PLoS ONE, 2011 BackgroundThe absence of certain genomic loci that are present in most of the virulent strains of Mycobacterium tuberculosis as well as lack of lasting memory responses are some of the major causes attributed to the non effectiveness of Bacille Calmette ...
Mairaj Ahmed Ansari +7 more
doaj +2 more sources
Journal of Drug Targeting, 1999 The biodistribution of orally and intravenously administered archaeosomes in mice was compared to that of archaeosomes containing either coenzyme Q10 (archaeosome-CoQ10), polyethylene glycol (archaeosome-PEG), or PEG plus CoQ10 (archaeosome-PEG-CoQ10).
Omri, A. +4 more
openaire +4 more sources
Homologous Prime-Boost Vaccination with OVA Entrapped in Self-Adjuvanting Archaeosomes Induces High Numbers of OVA-Specific CD8+ T Cells that Protect Against Subcutaneous B16-OVA Melanoma [PDF]
Vaccines, 2016 Homologous prime-boost vaccinations with live vectors typically fail to induce repeated strong CD8+ T cell responses due to the induction of anti-vector immunity, highlighting the need for alternative delivery vehicles. The unique ether lipids of archaea
Felicity C. Stark +2 more
doaj +2 more sources
Archaeosomes as novel antigen delivery systems
FEMS Microbiology Letters, 1997 The humoral immune response mounted in BALB/c mice against bovine serum albumin or cholera toxin B subunit was compared when the antigens were associated with liposomes composed of either archaeal ether lipids or conventional lipids. Antibody titres in sera from mice immunised intraperitoneally were elevated to an extent comparable to those achieved ...
Sprott, G., Tolson, D., Patel, G.
openaire +4 more sources
Archaeosomes as Drug and Vaccine Nanodelivery Systems
, 2006 Archaeosomes, liposomes made from the polar lipids extracted from the membranes of Archaea, have been extensively studied for potential applications in drug and vaccine delivery over the past decade only. Archaeosomes offer significant advantages as nanodelivery vesicles over conventional liposomes made from the ester lipids found in Eukarya and ...
Patel, G., Chen, W.
openaire +3 more sources
Chemical Biology & Drug Design, 2017 The ability of Archaea to adapt their membrane lipid compositions to extreme environments has brought in archaeosomes into consideration for the development of drug delivery systems overcoming the physical, biological blockades that the body exhibits against drug therapies.
Azade Attar +7 more
core +6 more sources
Asian Pacific Journal of Cancer Biology, 2017 In this study the effect of Archaeosomal Paclitaxel drug on Breast Cancer cell lines MDA-MB231 cells was evaluated. The experiments were conducted to assess the cytotoxicity of 7 Paclitaxel in free form and compare it with Archaeosomal form of the drug ...
Maral Mazloumi Tabrizi
doaj +1 more source
In Silico Prophage Analysis of Halobacterium salinarum ATCC 33170
Applied MicrobiologyThe extremophile Halobacterium salinarum is an aerobic archaeon that has adapted to thrive in high-salt environments such as salted fish, hypersaline lakes, and salterns. Halophiles have garnered significant interest due to their unique interactions with
Danielle L. Peters +3 more
doaj +2 more sources
Combination Therapy Using Human Papillomavirus L1/E6/E7 Genes and Archaeosome: A Nanovaccine Confer Immuneadjuvanting Effects to Fight Cervical Cancer [PDF]
Scientific Reports, 2020 Hesam Karimi +2 more
exaly +2 more sources