Results 21 to 30 of about 269 (141)
The potential of archaeosomes as carriers of pDNA into mammalian cells
Artificial Cells, Nanomedicine, and Biotechnology, 2015 This paper describes the formulation of archaeosomes and the evaluation of their abilities to facilitate in vitro DNA delivery. Lipids of the H.hispanica 2TK2 strain were used in archaeosome formation, which is formulated by mixing H.hispanica 2TK2 lipids with plasmid DNA encoding green fluorescent protein (GFP) or β-galactosidase (β-gal).
Turan, Kadir +3 more
core +6 more sources
Journal of Drug Targeting, 1999 The biodistribution of orally and intravenously administered archaeosomes in mice was compared to that of archaeosomes containing either coenzyme Q10 (archaeosome-CoQ10), polyethylene glycol (archaeosome-PEG), or PEG plus CoQ10 (archaeosome-PEG-CoQ10).
Omri, A. +4 more
openaire +4 more sources
Archaeosomes as novel antigen delivery systems
FEMS Microbiology Letters, 1997 The humoral immune response mounted in BALB/c mice against bovine serum albumin or cholera toxin B subunit was compared when the antigens were associated with liposomes composed of either archaeal ether lipids or conventional lipids. Antibody titres in sera from mice immunised intraperitoneally were elevated to an extent comparable to those achieved ...
Sprott, G., Tolson, D., Patel, G.
openaire +4 more sources
Vaccines, 2016 Homologous prime-boost vaccinations with live vectors typically fail to induce repeated strong CD8+ T cell responses due to the induction of anti-vector immunity, highlighting the need for alternative delivery vehicles. The unique ether lipids of archaea
Felicity C. Stark +2 more
doaj +2 more sources
Archaeosomes as Drug and Vaccine Nanodelivery Systems
, 2006 Archaeosomes, liposomes made from the polar lipids extracted from the membranes of Archaea, have been extensively studied for potential applications in drug and vaccine delivery over the past decade only. Archaeosomes offer significant advantages as nanodelivery vesicles over conventional liposomes made from the ester lipids found in Eukarya and ...
Patel, G., Chen, W.
openaire +3 more sources
In vitro evaluation of archaeosome vehicles for transdermal vaccine delivery
Journal of Liposome Research, 2017 Archaeosomes composed of archaeal total polar lipids (TPL) or semi-synthetic analog vesicles have been used as vaccine adjuvants and delivery systems in animal models for many years. Typically administered by intramuscular or subcutaneous injections, archaeosomes can induce robust, long-lasting humoral and cell-mediated immune responses against ...
Yimei Jia +10 more
openaire +3 more sources
Combination therapy using human papillomavirus L1/E6/E7 genes and archaeosome: a nanovaccine confer immuneadjuvanting effects to fight cervical cancer [PDF]
Scientific Reports, 2020 Hesam Karimi +2 more
exaly +2 more sources
Asian Pacific Journal of Cancer Biology, 2017 In this study the effect of Archaeosomal Paclitaxel drug on Breast Cancer cell lines MDA-MB231 cells was evaluated. The experiments were conducted to assess the cytotoxicity of 7 Paclitaxel in free form and compare it with Archaeosomal form of the drug ...
Maral Mazloumi Tabrizi
doaj +1 more source
In Silico Prophage Analysis of Halobacterium salinarum ATCC 33170
Applied MicrobiologyThe extremophile Halobacterium salinarum is an aerobic archaeon that has adapted to thrive in high-salt environments such as salted fish, hypersaline lakes, and salterns. Halophiles have garnered significant interest due to their unique interactions with
Danielle L. Peters +3 more
doaj +2 more sources
Synthetic archaeosome adjuvants
, 2009 Taiwan-Canada Bilateral Workshop: Glycosicence Workshop, Taipei, Taiwan, November ...
Whitfield, Dennis M., Sprott, Dennis G.
openaire +2 more sources