Results 81 to 90 of about 293 (137)

Archaeosomes induce long-term CD8 + cytotoxic response to entrapped soluble protein by the exogenous cytosolic pathway, in the absence of CD4 + T cell help

, 2000
The unique ether glycerolipids of Archaea can be formulated into vesicles (archaeosomes) with strong adjuvant activity for MHC class II presentation.
Sad, Subash, Patel, G., Sprott, G., Krishnan, Lakshmi, Subash Sad, G. Dennis Sprott, Lakshmi Krishnan, Girishchandra B. Patel   +7 more
core   +1 more source

Immunogenicity of SARS-CoV-2 spike antigens derived from Beta & Delta variants of concern. [PDF]

NPJ Vaccines, 2022
Akache B, Renner TM, Stuible M, Rohani N, Cepero-Donates Y, Deschatelets L, Dudani R, Harrison BA, Gervais C, Hill JJ, Hemraz UD, Lam E, Régnier S, Lenferink AEG, Durocher Y, McCluskie MJ.   +15 more
europepmc   +1 more source

Adjuvant potential of archaeal synthetic glycolipid mimetics critically depends on the glyco head group structure

, 2008
Subunit vaccines capable of providing protective immunity against the intracellular pathogens and cancers that kill millions of people annually require an adjuvant capable of directing a sufficiently potent cytotoxic T lymphocyte response to purified ...
Sprott, G., Whitfield, Dennis, Dicaire, C., Cote, J.   +3 more
core   +1 more source

Archaeosomal nanocarriers improve pharmacokinetics and bioavailability of vancomycin after oral administration

European Journal of Pharmaceutical Sciences
Vancomycin, a glycopeptide antibiotic, is typically administered intravenously (IV) for severe Gram-positive bacterial infections. While the oral route offers higher patient adherence, it is limited by poor mucosal transport, restricting its use to intestinal infections.
Viktor Sedlmayr, Julian Quehenberger, David Wurm, Mikko Gynther, Rebecca Vieth, Valerie Dürr, Pascal Gesse, Oliver Spadiut, Gert Fricker, Philipp Uhl   +9 more
openaire   +2 more sources

Nanotechnology in cervical cancer immunotherapy: Therapeutic vaccines and adoptive cell therapy. [PDF]

Front Pharmacol, 2022
Zhou X, Lian H, Li H, Fan M, Xu W, Jin Y.   +5 more
europepmc   +1 more source

Archaeosomes as novel antigen delivery systems1 [PDF]

FEMS Microbiology Letters, 2006
G.Dennis Sprott, Douglas L Tolson, Girishchandra B Patel   +2 more
openaire   +1 more source

Nanotechnology Platform for Advancing Vaccine Development against the COVID-19 Virus. [PDF]

Diseases, 2023
Chowdhury N, Kundu A.
europepmc   +1 more source

Self-adjuvanting cancer nanovaccines. [PDF]

J Nanobiotechnology, 2022
Liao Z, Huang J, Lo PC, Lovell JF, Jin H, Yang K.   +5 more
europepmc   +1 more source

Archaeosomes induce enhanced cytotoxic T lymphocyte responses to entrapped souble antigens in the absence of IL-12 and protect against tumor challenge.

, 2003
Archaeosome adjuvants formulated as archaeal ether glycerolipid vesicles induce strong CD4(+) as well as CD8(+) CTL responses to entrapped soluble antigens.
Sad, Subash, Patel, G., Sprott, G., Krishnan, Lakshmi   +3 more
core   +1 more source

Special Issue: Novel Vaccines and Vaccine Technologies for Emerging Infections. [PDF]

Vaccines (Basel)
Chen W, Li X, Kamen AA.
europepmc   +1 more source