Results 81 to 90 of about 269 (141)

Immunization of mice with lipopeptide antigens encapsulated in novel liposomes prepared from the polar lipids of various Archaeobacteria elicits rapid and prolonged specific protective immunity against infection with the facultative intracellular pathogen, Listeria monocytogenes

, 2001
Protective immunity to intracellular bacterial pathogens usually requires the participation of specific CD8+ T cells. Natural exposure of the host to sublethal infection, or vaccination with attenuated live vaccines are the most effective means of ...
Conlan, J., Patel, G., Sprott, G., Willick, Gordon, Krishnan, Lakshmi   +4 more
core   +1 more source

Archaeosomes: New Generation of Liposomes Based on Archaeal Lipids for Drug Delivery and Biomedical Applications. [PDF]

ACS Omega, 2023
Santhosh PB, Genova J.
europepmc   +1 more source

Archaeobacterial ether lipid liposomes (archaeosomes) as novel vaccine and drug delivery systems

, 1999
Liposomes are artificial, spherical, closed vesicles consisting of one or more lipid bilayer(s). Liposomes made from ester phospholipids have been studied extensively over the last 3 decades as artificial membrane models.
Patel, G., Sprott, G.
core  

PEGylated liposomes enhance the effect of cytotoxic drug: A review. [PDF]

Heliyon, 2023
Taher M, Susanti D, Haris MS, Rushdan AA, Widodo RT, Syukri Y, Khotib J.   +6 more
europepmc   +1 more source

New generation of liposomes called archaeosomes based on natural or synthetic archaeal lipids as innovative formulations for drug delivery.

, 2009
International audienceArchaeosomes made from natural archaeal membrane lipids and/or synthetic lipid analogues have been extensively studied for potential applications in drug and vaccine delivery over the past decade only.
Cammas-Marion, Sandrine, Lemiègre, Loïc, Benvegnu, Thierry   +2 more
core   +1 more source

Immunogenicity of SARS-CoV-2 spike antigens derived from Beta & Delta variants of concern. [PDF]

NPJ Vaccines, 2022
Akache B, Renner TM, Stuible M, Rohani N, Cepero-Donates Y, Deschatelets L, Dudani R, Harrison BA, Gervais C, Hill JJ, Hemraz UD, Lam E, Régnier S, Lenferink AEG, Durocher Y, McCluskie MJ.   +15 more
europepmc   +1 more source

Archaeosomal nanocarriers improve pharmacokinetics and bioavailability of vancomycin after oral administration

European Journal of Pharmaceutical Sciences
Vancomycin, a glycopeptide antibiotic, is typically administered intravenously (IV) for severe Gram-positive bacterial infections. While the oral route offers higher patient adherence, it is limited by poor mucosal transport, restricting its use to intestinal infections.
Viktor Sedlmayr, Julian Quehenberger, David Wurm, Mikko Gynther, Rebecca Vieth, Valerie Dürr, Pascal Gesse, Oliver Spadiut, Gert Fricker, Philipp Uhl   +9 more
openaire   +2 more sources

Structural characterization of archaeal lipid mucosal vaccine adjuvant and delivery (AMVAD) formulations prepared by different protocols and their efficacy upon intranasal immunization of mice

, 2008
Intranasal administration of ovalbumin (OVA) formulated in an archaeal lipid mucosal vaccine adjuvant and delivery (AMVAD) system prepared by the addition of CaCl2 to small unilamellar archaeosomes (liposomes made from archaeal polar lipids) containing ...
Patel, G., Ponce, Amalia, Zhou, Hongyan, Chen, W.   +3 more
core   +1 more source

Nanotechnology in cervical cancer immunotherapy: Therapeutic vaccines and adoptive cell therapy. [PDF]

Front Pharmacol, 2022
Zhou X, Lian H, Li H, Fan M, Xu W, Jin Y.   +5 more
europepmc   +1 more source

The Role of CD8+ T Cell Phenotype and Cytotoxicity on Cancer Immunotherapy

, 2011
Cancer vaccines can fail despite the induction of large numbers of CD8+ T cells. Two categories of memory CD8+ T cells have been defined; central memory (TCM, IL-7RαhighCD44highCD62Lhigh) and effector memory (TEM, IL-7RαhighCD44highCD62Llow).
Stark, Felicity
core