Results 61 to 70 of about 269 (141)
Tetraether archaeal lipids promote long‐term survival in extreme conditions
Molecular Microbiology, Volume 121, Issue 5, Page 882-894, May 2024.Unique archaeal lipid membrane composition, including membrane‐spanning, tetraether lipids, presumably contribute to survival in extreme pH, temperature, and salinity. The biosynthesis of tetraether lipids in the model species Thermococcus kodakarensis promotes survival at high temperatures, and we demonstrate that alternative lipid species are ...
Geraldy Lie Stefanus Liman +6 more
wiley +1 more source
Effect of Growth Medium pH of Aeropyrum pernix on Structural Properties and Fluidity of Archaeosomes
Archaea, Volume 2012, Issue 1, 2012., 2012 The influence of pH (6.0; 7.0; 8.0) of the growth medium of Aeropyrum pernix K1 on the structural organization and fluidity of archaeosomes prepared from a polar‐lipid methanol fraction (PLMF) was investigated using fluorescence anisotropy and electron paramagnetic resonance (EPR) spectroscopy.
Ajda Ota +4 more
wiley +1 more source
International Journal of Hypertension, Volume 2024, Issue 1, 2024.The lipid‐based drug delivery system (LBDDS) is a well‐established technique that is anticipated to bring about comprehensive transformations in the pharmaceutical field, impacting the management and administration of drugs, as well as treatment and diagnosis.
Preeti +10 more
wiley +1 more source
Archaeosomes and Tetraether Lipid Liposome
Pharmaceutical Sciences and Research, 2012 Archaea have phytanyl ether lipids which is one of the characteristics that separates them from bacteria and eukaryotes. Some archaea have also unique membrane spanning tetrae- ther lipids (T EL); in Sulfolobus and Ihermoplasma species these TELmake up the majority of total membrane lipids.
openaire +1 more source
In vitro assessment of archaeosome stability for oral delivery of vaccines
, 1999 39th Interscience Conference on Antimicrobial Agents and Chemotherapy, September 26-29th 1999, San Franciso CA ...
Patel, G.B., Agnew, B.J., Sprott, G.D.
openaire +2 more sources
Physical Properties and Membrane Packing in Hybrid Archaeosomes [PDF]
Biophysical Journal, 2015 In this study, we have characterized the physical properties of liposomes made of archaeal bipolar tetraether lipids (BTL) and “conventional” monopolar diester lipids (termed as hybrid archaeosomes). We used the polar lipid fraction E (PLFE) isolated from the thermoacidophilic archaeon Sulfolobus acidocaldarius as the BTL component of the hybrid ...
Ayesa, Umme, Chong, Parkson L.G.
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Evaluation of the safety profile archaeosome adjuvants in a mouse model
, 2003 Modern Vaccines Adjuvants and Delivery Systems Conference, June 4-6, 2003 Dublin ...
Patel, G.B., Omri, A., Sprott, G.D.
openaire +2 more sources
Preparation and Characterization of Stealth Archaeosomes Based on a Synthetic PEGylated Archaeal Tetraether Lipid. [PDF]
J Drug Deliv, 2011 International audienceThe present studies were focused on the formation and characterization of sterically stabilized archaeosomes made from a synthetic PEGylated archaeal lipid.
Barbeau J +3 more
europepmc +2 more sources
Archaeosomes varying in lipid composition differ in receptor mediated endocytosis and differentially adjuvant immune responses to entrapped antigen [PDF]
, 2003 Archaeosomes prepared from total polar lipids extracted from six archaeal species with divergent lipid compositions had the capacity to deliver antigen for presentation via both MHC class I and class II pathways.
Sad, Subash +5 more
core
Archaeobacterial ether lipid liposomes as vaccine adjuvants
, 2003 Archaeosomes are mixed adjuvants capable of promoting strong humoral, cell-mediated (Th1), cytotoxic T-cell\u2013mediated (Th1), and cytotoxic T-cell responses to entrapped protein antigens.
Patel, G., Sprott, G., Krishnan, Lakshmi
core +1 more source