Results 71 to 80 of about 293 (137)

Vesicular and Planar Membranes of Archaea Lipids: Unusual Physical Properties and Biomedical Applications. [PDF]

Int J Mol Sci, 2022
Chong PL, Chang A, Yu A, Mammedova A.
europepmc   +1 more source

Archaeobacterial ether lipid liposomes (archaeosomes) as novel vaccine and drug delivery systems

, 1999
Liposomes are artificial, spherical, closed vesicles consisting of one or more lipid bilayer(s). Liposomes made from ester phospholipids have been studied extensively over the last 3 decades as artificial membrane models.
Patel, G., Sprott, G.
core   +1 more source

Photoprotective archaeosomes made of lipids extracted with bio-solvents.

Processes
Archaea lipids are a source of new biomaterials for pharmaceutical and nanomedical applications; however, their classic extraction method relies on chloroform and methanol, toxic solvents that conflict with green chemistry principles. In this paper we explore the performance of an eco-friendly method for the extraction of total lipids from the ...
Yamila Roxana Simioni, Victoria Rebeca Dana González Epelboim, Gustavo Apezteguia, Leticia Herminia Higa, Eder Lilia Romero, Maria Jose Morilla   +5 more
openaire   +1 more source

Immunization of mice with lipopeptide antigens encapsulated in novel liposomes prepared from the polar lipids of various Archaeobacteria elicits rapid and prolonged specific protective immunity against infection with the facultative intracellular pathogen, Listeria monocytogenes

, 2001
Protective immunity to intracellular bacterial pathogens usually requires the participation of specific CD8+ T cells. Natural exposure of the host to sublethal infection, or vaccination with attenuated live vaccines are the most effective means of ...
Conlan, J., Patel, G., Sprott, G., Willick, Gordon, Krishnan, Lakshmi, Lakshmi Krishnan, Gordon E. Willick, G.Dennis Sprott, J.Wayne Conlan, Girishchandra B. Patel   +9 more
core   +1 more source

A structural comparison of the total polar lipids from the human archaea Methanobrevibacter smithii and Methanosphaera stadtmanae and its relevance to the adjuvant activities of their liposomes

, 1999
Mice were immunized with bovine serum albumin (BSA) entrapped within archaeosomes (i.e. liposomes) composed of the total polar lipids (TPL) from the two methanogenic archaea common to the human digestive tract.
Patel, G., Sprott, G., Pelletier, A., Dicaire, C., Brisson, J., Krishnan, Lakshmi, Deschatelets, L., Jean-Robert Brisson, G.Dennis Sprott, Lise A Deschatelets, Chantal J Dicaire, Lakshmi Krishnan, Girishchandra B Patel, Anne K Pelletier   +13 more
core   +1 more source

Archaeosomes: New Generation of Liposomes Based on Archaeal Lipids for Drug Delivery and Biomedical Applications. [PDF]

ACS Omega, 2023
Santhosh PB, Genova J.
europepmc   +1 more source

New generation of liposomes called archaeosomes based on natural or synthetic archaeal lipids as innovative formulations for drug delivery.

, 2009
International audienceArchaeosomes made from natural archaeal membrane lipids and/or synthetic lipid analogues have been extensively studied for potential applications in drug and vaccine delivery over the past decade only.
Cammas-Marion, Sandrine, Lemiègre, Loïc, Benvegnu, Thierry, Sandrine Cammas-Marion, Loic Lemiegre, Thierry Benvegnu   +5 more
core   +1 more source

Structural characterization of archaeal lipid mucosal vaccine adjuvant and delivery (AMVAD) formulations prepared by different protocols and their efficacy upon intranasal immunization of mice

, 2008
Intranasal administration of ovalbumin (OVA) formulated in an archaeal lipid mucosal vaccine adjuvant and delivery (AMVAD) system prepared by the addition of CaCl2 to small unilamellar archaeosomes (liposomes made from archaeal polar lipids) containing ...
Patel, G., Ponce, Amalia, Zhou, Hongyan, Chen, W.   +3 more
core   +1 more source

An Evaluation of Novel Archaeosome Lipids and Immunostimulatory Molecules as Potential Vaccine Adjuvants

, 2010
Peer reviewed: YesNRC publication ...
Sprott, D. G., Whitfield, D. M., Yeung, A.   +2 more
core   +1 more source

PEGylated liposomes enhance the effect of cytotoxic drug: A review. [PDF]

Heliyon, 2023
Taher M, Susanti D, Haris MS, Rushdan AA, Widodo RT, Syukri Y, Khotib J.   +6 more
europepmc   +1 more source