Results 111 to 120 of about 13,364 (264)

Structural studies and functional engineering of NanX: an anhydro‐sialic acid transporter from Escherichia coli

FEBS Open Bio, EarlyView.
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty, Kelsi R. Hall, Zachary D. Tillett, Liam S. Turk, James S. Davies, Michael J. Currie, Hamish G. Brown, Sepideh Valimehr, Peter D. Mace, Andrew E. Whitten, Santosh Panjikar, Eric Hanssen, Rachel A. North, Renwick C.J. Dobson   +13 more
wiley   +1 more source

A Winter-to-Summer Transition of Bacterial and Archaeal Communities in Arctic Sea Ice. [PDF]

Microorganisms, 2022
Thiele S, Storesund JE, Fernández-Méndez M, Assmy P, Øvreås L.   +4 more
europepmc   +1 more source

Purification and preparation of Marchantia polymorpha Auxin Response Factor 2 for phase separation studies

FEBS Open Bio, EarlyView.
We describe detailed protocols for the purification and preparation of Marchantia polymorpha Auxin Response Factor 2 (MpARF2). This protein is fused to an MBP solubility tag and an mNG fluorescent tag and is purified from Escherichia coli. The presented procedures make it possible to study MpARF2 assemblies, which could arise from phase separation ...
Bas Janssen, Robin Romein, Willy A. M. van den Berg, Simon Lindhoud, Jan Willem Borst, Carlo P. M. van Mierlo   +5 more
wiley   +1 more source

High Levels of Microplastics in the Arctic Sea Ice Alga Melosira arctica, a Vector to Ice-Associated and Benthic Food Webs. [PDF]

Environ Sci Technol, 2023
Bergmann M, Allen S, Krumpen T, Allen D.
europepmc   +1 more source

Ice in Arctic Seas [PDF]

Nature, 1932
openaire   +1 more source

Protocol for quantifying miRNA trafficking across the endosomal membrane

FEBS Open Bio, EarlyView.
An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh, Kamalika Mukherjee, Suvendra N. Bhattacharyya   +2 more
wiley   +1 more source

Arctic sea-ice loss is projected to lead to more frequent strong El Niño events. [PDF]

Nat Commun, 2022
Liu J, Song M, Zhu Z, Horton RM, Hu Y, Xie SP.   +5 more
europepmc   +1 more source

Multistability in Arctic Sea Ice

Arctic sea ice has been noted to be in decline throughout the era of satellite observations. This decline was especially steep between 1995 and 2012, although the rate of decline has decreased considerably since then. The reconstructed state-space projection in two dimensions of Arctic sea ice extent by summer minima shows clear evidence of ...
openaire   +1 more source

ALDOA Promotes Glycolysis and NLRP3/GSDMD Pyroptosis to Accelerate ALS Progression

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is characterized by progressive motor neuron degeneration. Glycolytic dysregulation is implicated in disease progression, yet the underlying mechanisms remain unclear. This study investigates how Aldolase A (ALDOA) drives ALS progression through glycolysis‐mediated motor neuron pyroptosis.
Kaixin Yan, Yan Jiang, Yuxuan Yong, Tianshuo Zhang, Niannian Zhang, Qianqian Zeng, Xue Gong, Li Meng, Fangfang Bi, Yongmin Liu   +9 more
wiley   +1 more source

Database of daily Lagrangian Arctic sea ice parcel drift tracks with coincident ice and atmospheric conditions. [PDF]

Sci Data, 2023
Horvath S, Boisvert L, Parker C, Webster M, Taylor P, Boeke R, Fons S, Stewart JS.   +7 more
europepmc   +1 more source