Results 131 to 140 of about 2,283,779 (307)
FEBS Open Bio, EarlyView.In this study, a novel esterase from the thermoacidophilic archaeon Thermoplasma acidophilum was biochemically and structurally characterized. Our results demonstrate that Ta0887 is a highly thermostable esterase that preferentially hydrolyzes p‐nitrophenyl hexanoate and possesses an α‐helical cap domain that likely contributes to its substrate ...
Alejandro Delgado‐Rey +4 more
wiley +1 more source
Shipborne visual observations of Arctic sea ice during Lance cruise LA1408
, 2018 Shipborne visual observations of Arctic sea ice during Lance cruise ...
Jennifer King (8022686), King, Jennifer
core +1 more source
FEBS Open Bio, EarlyView.The two catalytic subunits of typhoid toxin dissociate from the holotoxin in the ER of an intoxicated cell, but only CdtB exits the ER to generate immunosuppressive effects. PltA is retained in the ER and sequestered from its cytosolic target, thus allowing the anti‐inflammatory effects of CdtB to promote intestinal colonization.
Maria C. Zabala‐Rodriguez +4 more
wiley +1 more source
Cell surface CD11c as a neutrophil aging marker molecule
FEBS Open Bio, EarlyView.Cell surface CD11chi neutrophils were more aged and had better phagocytic function than CD11c−/lo neutrophils. Transcriptomic analysis of CD11chi neutrophils and CD11c−/lo neutrophils in pediatric population showed that the most difference was seen in infants.
Sophia Koutsogiannaki +5 more
wiley +1 more source
The C‐terminal domain of yeast Arginyltransferase1 is essential for its catalytic activity
FEBS Open Bio, EarlyView.Arginyltransferase 1 (Ate1), a eukaryotic enzyme, catalyses arginylation, transferring arginine from tRNA‐Arg to the amino terminus of the target protein. Overexpression of Ate1 in yeast is lethal and is dependent on arginylation. This study elucidates how mutations in the cofactor‐binding and active site of Ate1 and truncation of its structural ...
Vikas Kumar Yadav +4 more
wiley +1 more source
Atmospheric Conditions Preceeding Very Rapid Sea Ice Loss Events [PDF]
, 2019 Even though the observed amplified warming trend in the Arctic region is well-established in theory through climate feedbacks and reproduced in global climate model projections, the same global climate models underestimate the corresponding decline in ...
Frank, Madeline Clark
core
Shipborne visual observations of Arctic sea ice during Louis S. St-Laurent cruise LSL0608
, 2018 Shipborne visual observations of Arctic sea ice during Louis S.
Hutchings, Jennifer K +1 more
core +1 more source
Stable Isotopes as Tracers for Freshwater Fluxes into the North Atlantic
, 2010 The Arctic acts as both an indicator and a facilitator of global climate change. Many studies have identified the manifold changes in the Arctic hydrological system resulting from global warming.
Cox, Katharine A.
core +1 more source
Type I interferons modulate autophagy to shape gemcitabine response in pancreatic cancer cells
FEBS Open Bio, EarlyView.Type I interferons differentially modulate autophagy and the response of pancreatic cancer cells to gemcitabine. IFNα2b stimulates autophagic flux and protects cells from gemcitabine‐induced cell death, contributing to chemoresistance. In contrast, IFNβ1a inhibits autophagosome formation and enhances gemcitabine‐induced cell death, resulting in ...
Lucy E. Bonilla +10 more
wiley +1 more source
Sea Ice Latent Heat Becomes More Active in the Arctic Sea Ice Energy Budget
Geophysical Research LettersArctic sea ice has experienced rapid decrease in recent decades. The sea ice property changes have altered its thermodynamic processes, enhancing the heat exchange among atmosphere‐ocean‐ice surface.
Yuang Liu +3 more
doaj +1 more source