Results 121 to 130 of about 162,083 (309)
Enhancing sea ice knowledge through assimilation of sea ice thickness from ENVISAT and CS2SMOS [PDF]
Arctic sea ice extent has declined significantly over the past four decades, opening up the Arctic to shipping and resource extraction while also impacting wildlife and local communities.
N. Williams +3 more
doaj +1 more source
Arctic Research on Thin Ice: Consequences of Arctic Sea Ice Loss
Scientists embarked on a 6-month expedition in the Arctic Ocean to study the thinning sea ice cover, improve our understanding of sea ice loss effects, and help predict future changes.
Mats Granskog +5 more
openaire +1 more source
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Evaluation of the ArcIOPS sea ice forecasts during 2021–2023
The operational sea ice forecasts from the Arctic Ice Ocean Prediction System (ArcIOPS) during 2021–2023 are validated against satellite-retrieved sea ice concentration and drift data, in situ and reanalyzed sea ice thickness data.
Xi Liang +5 more
doaj +1 more source
Foxes and food subsidies: anthropogenic food use by red and Arctic foxes, and effects on Arctic fox survival, on the Arctic Coastal Plain of Alaska [PDF]
Thesis (M.S.) University of Alaska Fairbanks, 2013Food subsidies have the potential to impact wildlife on the Arctic Coastal Plain of Alaska. Red foxes (Vulpes vulpes (L., 1758)) expanded their range into Arctic regions during the 20th century, and the ...
Savory, Garrett
core
Sea ice friction and Arctic sea ice dynamics
A series of double-shear experiments were undertaken in the Environmental Test Basin at the Hamburgische Shiffbau-Versuchsanstalt (HSVA) in Hamburg. The aim of these experiments was to improve understanding of transient behaviour in sea ice friction. To this end we have fitted our experimental results to a rate- and state- dependent model of friction ...
Lishman, Ben +3 more
openaire +1 more source
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
The extent of Arctic sea ice dropped to 3.41 million square kilometers on 16 September, 760,000 square kilometers below the minimum ice extent in 2007, which had been the low mark since the satellite record began in 1979, the National Snow and Ice Data Center (NSIDC) announced.
openaire +1 more source
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source

