Results 81 to 90 of about 161,658 (309)

Changes in the Arctic Traffic Occupancy and Their Connection to Sea Ice Conditions from 2015 to 2020

open access: yesRemote Sensing
Arctic shipping activities are increasing in the context of sea ice decline. However, research gaps persist in studying recent Arctic shipping activities across various vessel types and their connection with sea ice conditions.
Yihan Liu   +4 more
doaj   +1 more source

Shipping Through Sea Ice: Impacts on Marine Habitats and Best Practices [PDF]

open access: yes, 2017
As the result of Arctic climate change and an increase in shipping season length, there is a growing interest in Arctic shipping operations. Sea ice serves as an important habitat for marine mammals, therefore, shipping through sea ice could lead to ...

core  

Faster Arctic sea ice retreat in CMIP5 than in CMIP3 due to volcanoes [PDF]

open access: yes, 2016
The downward trend in Arctic sea ice extent is one of the most dramatic signals of climate change during recent decades. Comprehensive climate models have struggled to reproduce this, typically simulating a slower rate of sea ice retreat than has been ...
Eisenman, Ian, Rosenblum, Erica
core   +2 more sources

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

open access: yesMolecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert   +13 more
wiley   +1 more source

Status and trends in the structure of Arctic benthic food webs [PDF]

open access: yesPolar Research, 2015
Ongoing climate warming is causing a dramatic loss of sea ice in the Arctic Ocean, and it is projected that the Arctic Ocean will become seasonally ice-free by 2040.
Monika Kędra   +13 more
doaj   +1 more source

How tropical Pacific surface cooling contributed to accelerated sea ice melt from 2007 to 2012 as ice is thinned by anthropogenic forcing [PDF]

open access: yes, 2019
Over the past 40 years the Arctic sea ice minimum in September has declined. The period between 2007 and 2012 showed accelerated melt contributed to the record minima of 2007 and 2012.
Baxter, Ian
core  

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

open access: yesMolecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak   +8 more
wiley   +1 more source

Direct determination of the air-sea CO₂ gas transfer velocity in Arctic sea-ice regions [PDF]

open access: yes, 2017
The Arctic Ocean is an important sink for atmospheric CO₂. The impact of decreasing sea-ice extent and expanding marginal ice zones on Arctic air-sea CO₂ exchange depends on the rate of gas transfer in the presence of sea ice.
Anderson, LG   +8 more
core   +1 more source

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

open access: yesMolecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié   +16 more
wiley   +1 more source

Impacts of ocean albedo alteration on Arctic sea ice restoration and Northern Hemisphere climate [PDF]

open access: yes, 2015
The Arctic Ocean is expected to transition into a seasonally ice-free state by mid-century, enhancing Arctic warming and leading to substantial ecological and socio-economic challenges across the Arctic region.
Caldeira, Ken   +2 more
core   +1 more source

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