Results 121 to 130 of about 24,202 (294)
, 2002 Objectives. To evaluate the frequency, morphology, and pathogenesis (primary or secondary) of the abnormally developed medullary arcuate nucleus (ARCn) in stillbirths. Methods.
L. Matturri +5 more
core +1 more source
Diet-induced adaptive thermogenesis requires neuropeptide FF receptor-2 signalling
Nature Communications, 2018 Excess caloric intake leads to increased thermogenesis in brown adipose tissue, to limit weight gain. Here, the authors show that neuropeptide FF receptor-2 signalling promotes thermogenesis via control of NPY expression in the arcuate nucleus, and that ...
Lei Zhang +10 more
doaj +1 more source
Advanced Science, EarlyView.ABSTRACT Vascularization remains a major obstacle in tissue engineering. Here, we introduce a bioprinting strategy to generate centimeter‐scale, self‐organizing “mother vessel” constructs from iPSC‐derived hiMPCs. By optimizing bioink composition, printing was accomplished in a single‐step approach. Within one week, hiMPCs differentiated into both CD31+
Leyla E. Dogan +5 more
wiley +1 more source
Light‐Activated Isolation of High‐Quality Mitochondria for Therapeutic Transplantation
Angewandte Chemie, EarlyView.The Light‐Activated Mitochondrial Isolation (LAMI) platform enables the selective and non‐destructive isolation of high‐purity, metabolically active mitochondria. By integrating modular, ligand‐programmable magnetic probes with photo‐cleavable release, LAMI overcomes long‐standing limitations of conventional isolation methods and provides a robust ...
Hui Liu +12 more
wiley +2 more sources
, 2004 Maternal smoking during pregnancy is the most important risk factor for sudden perinatal and infant death in more industrialized countries. The frequent observation of hypoplasia of the arcuate nucleus in the brainstem of these victims prompted the ...
L. Matturri +3 more
core +1 more source
Advanced Science, EarlyView.Eight AB‐type 2D inorganic electrides with negatively charged transition metals are theoretically designed. Their monolayers exhibit intrinsic magnetic ordering, rich topological phases, and ultralow work functions. Supported metal Ru on these 2D inorganic electrides effectively alleviates hydrogen poisoning and enables efficient ammonia synthesis ...
Qianwen Zhang +6 more
wiley +1 more source
Mitochondria‐Damaging Self‐Reporting Probe for Cancer Therapy
Angewandte Chemie, EarlyView.We developed a class of self‐reporting cationic chemotherapeutic probes that selectively induce mitochondrial damage and apoptosis in cancer cells. Their unique mitochondria‐to‐nucleus fluorescence migration enables real‐time visualization of the therapeutic process. ABSTRACT Mitochondrial damage induced by chemotherapeutic agents through disruption of
Hai Xu +10 more
wiley +2 more sources
Nature Communications, 2019 Despite the crucial physiological processes governed by neurons in the hypothalamic arcuate nucleus (ARC), the developmental pathways and regulators for ARC neurons remain understudied.
Christian Huisman +9 more
doaj +1 more source
Arcuate nucleus – a gateway for insulin's action on sympathetic activity
The Journal of Physiology, 2011 Landsberg and colleagues in the 1980s first showed that an increase in the level of circulating insulin results in an increase in sympathetic activity, both in humans and in rats, even under conditions where the level of plasma glucose is clamped (for review see Landsberg, 2001).
openaire +3 more sources