Results 91 to 100 of about 23,715 (250)
Food Science &Nutrition, Volume 14, Issue 6, June 2026.Hydroxy‐alpha‐sanshool could modulate the expression of appetite‐related factors and the composition of intestinal microbiota in mice fed with a high‐fat diet by regulating food intake and maintaining energy homeostasis, which is consistent with the involvement of the gut‐brain axis in this regulatory mechanism.
Tianting Luo +6 more
wiley +1 more source
Frontiers in Endocrinology, 2014 Nutrients created by the digestion of food are proposed to active G protein coupled receptors on the luminal side of enteroendocrine cells e.g. the L-cell. This stimulates the release of gut hormones.
Carmen Sobrino Crespo +5 more
doaj +1 more source
Cilia in Nervous System Development, Function, and Disease
MedComm – Future Medicine, Volume 5, Issue 2, June 2026.Cilia are evolutionarily conserved organelles that function as essential sensory and motility platforms in the nervous system. This review outlines key cilia‐dependent signaling pathways and their roles in neural development and function. Furthermore, it highlights how ciliary dysfunction can lead to a variety of neurological disorders, known as ...
Qingchao Li, Anqi Zhang, Ting Song
wiley +1 more source
MCH axons in the arcuate nucleus.
, 2013 Photomicrographs illustrating the MCH labeling in the arcuate nucleus (ARH) in mouse (A and B) or rat (C and D) hypothalamus. In mouse, few MCH fibers were observed in the ARH whereas a dense MCH inputs were present in a ventral part of the rat ARH.
Gabrielle Franchi-Bernard (359652) +5 more
core +1 more source
Obesity, Volume 34, Issue S1, Page 77-87, June 2026.This study identifies G protein‐coupled receptor 17 (Gpr17) as a novel regulator of leptin and insulin sensitivity. Using complementary knockout models, we demonstrate that Gpr17 deletion enhances energy expenditure, restores leptin responsiveness, and improves insulin sensitivity, revealing Gpr17 as a potential therapeutic GPCR target for obesity and ...
Xun Sun +8 more
wiley +1 more source
A direct neurokinin B projection from the arcuate nucleus regulates magnocellular vasopressin cells of the supraoptic nucleus [PDF]
, 2015 Central administration of neurokinin B (NKB) agonists stimulates immediate early gene expression in the hypothalamus and increases secretion of vasopressin from the posterior pituitary through a mechanism that depends on the activation of neurokinin ...
Ludwig, Mike +6 more
core +1 more source
Molecular MetabolismIn rodent models of type 2 diabetes, a single intracerebroventricular (icv) injection of fibroblast growth factor 1 (FGF1) induces sustained remission of hyperglycemia. Overactive agouti-related peptide (AgRP) neurons, located in the hypothalamic arcuate
Nadia N. Aalling +12 more
doaj +1 more source
Diabetes, Obesity and Metabolism, Volume 28, Issue 6, Page 5184-5194, June 2026.ABSTRACT Aims Semaglutide is a GLP‐1 receptor agonist for the treatment of type 2 diabetes and obesity. Its clinical effects are well established, but the underlying mechanisms remain unclear. This study aims to use computational modelling to generate hypotheses about semaglutide's long‐term metabolic (body weight, net energy intake, blood glucose ...
Vivan C. W. Kennis, Natal A. W. van Riel
wiley +1 more source
Metabolic and serotonergic modulation of hypothalamic arcuate nucleus neurones in vitro [PDF]
1. The effects of glucose on the electrophysiological properties of rat hypothalamic arcuate nucleus (ARC) neurones were investigated. Neurones were recorded in 10 mM (hyperglycaemic) and 2 mM (euglycaemic) glucose-containing aCSF.
Saker, Louise
core
MCT2 is localized in orexigenic neurons of the arcuate nucleus.
, 2013 (a–c) Low magnification images of the ventro-medial hypothalamus, analyzed by immunohistochemistry using anti-AgRP (red) and anti-NPY (blue) antibodies. Ventricular arcuate nucleus neurons co-express AgRP and NPY (c).
Claudio Carril (407760) +6 more
core +1 more source