Results 71 to 80 of about 287,250 (294)
Chest, 2012 Obesity prevalence continues to increase globally, with figures exceeding 30% of some populations. Patients who are obese experience alterations in baseline pulmonary mechanics, including airflow obstruction, decreased lung volumes, and impaired gas exchange. These physiologic changes have implications in many diseases, including ARDS.
Kathryn, Hibbert +2 more
openaire +2 more sources
Association Between Ventilatory Settings and Development of Acute Respiratory Distress Syndrome in Mechanically Ventilated Patients Due to Brain Injury [PDF]
, 2017 PURPOSE: In neurologically critically ill patients with mechanical ventilation (MV), the development of acute respiratory distress syndrome (ARDS) is a major contributor to morbidity and mortality, but the role of ventilatory management has been ...
Amin, P +27 more
core +1 more source
Advanced Intelligent Systems, EarlyView.This study provides an introduction to Bayesian optimisation targeted for experimentalists. It explains core concepts, surrogate modelling, and acquisition strategies, and addresses common real‐world challenges such as noise, constraints, mixed variables, scalability, and automation.
Chuan He +2 more
wiley +1 more source
Metabolic signatures of ARDS and ARDS heterogeneity [PDF]
American Journal of Physiology-Lung Cellular and Molecular Physiology, 2021 Lucile Neyton, Carolyn S. Calfee
openaire +2 more sources
Novel anti-tumour necrosis factor receptor-1 (TNFR1) domain antibody prevents pulmonary inflammation in experimental acute lung injury. [PDF]
, 2018 BACKGROUND: Tumour necrosis factor alpha (TNF-α) is a pleiotropic cytokine with both injurious and protective functions, which are thought to diverge at the level of its two cell surface receptors, TNFR1 and TNFR2.
core +2 more sources
Archaeological Prospection, EarlyView.ABSTRACT The Carnac alignments in Morbihan (France) are among the most famous Neolithic sites of the world. Paradoxically, they have benefited little from a thorough renewal of archaeological data over the past century. There are many reasons for this, but it is mainly because the site has been regarded more as a monument to visit and protect than as ...
Guillaume Bruniaux +6 more
wiley +1 more source
Elevated plasma levels of TIMP-3 are associated with a higher risk of acute respiratory distress syndrome and death following severe isolated traumatic brain injury. [PDF]
, 2018 BackgroundComplications after injury, such as acute respiratory distress syndrome (ARDS), are common after traumatic brain injury (TBI) and associated with poor clinical outcomes.
Calfee, Carolyn S +8 more
core
Absolute electrical impedance tomography (aEIT) guided ventilation therapy in critical care patients: simulations and future trends [PDF]
, 2010 Thoracic electrical impedance tomography (EIT) is a noninvasive, radiation-free monitoring technique whose aim is to reconstruct a cross-sectional image of the internal spatial distribution of conductivity from electrical measurements made by injecting ...
Brown, B.H. +5 more
core +2 more sources
A phase 2 trial of hydroxychloroquine in individuals at risk for rheumatoid arthritis
Arthritis &Rheumatology, Accepted Article.Background Individuals with serum elevations of anti‐cyclic citrullinated peptide (anti‐CCP) antibodies are at increased risk for future rheumatoid arthritis (RA). No pharmacologic interventions have been approved for the prevention of RA in such ‘at‐risk’ individuals. However, hydroxychloroquine (HCQ) is used without supporting clinical trial evidence.
Kevin D. Deane +33 more
wiley +1 more source
Arthritis &Rheumatology, Accepted Article.Background The treatment landscape for systemic sclerosis‐associated interstitial lung disease (SSc‐ILD) has evolved with increasing immunosuppressive (IST) and anti‐fibrotic therapies available. However, their real‐world use remains unclear. Objectives To analyze treatment trends and the effect of IST and anti‐fibrotic therapies on ILD progression ...
Corrado Campochiaro +17 more
wiley +1 more source