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Tracing the Evolution and Recombination Events of Neurotropic Arenaviridae Viruses: a Bioinformatics Approach. [PDF]
Neuro-SignalsLassa virus is a member of the Arenaviridae family, a major cause of viral hemorrhagic fever. This virus is associated with severe neurological complications in a select group of patients.
Meaad Hussein Al-Abadi, B. Al-Nuaimi
semanticscholar +2 more sources
Identification of epitope-specific T cell responses to Lassa by genome-wide antigen screening and conservation across Arenaviridae 4344 [PDF]
Journal of ImmunologyCD4 and CD8 T cells play a key role in clearing Arenaviridae infections, even before the appearance of neutralizing antibodies. Thus, while vaccine strategies that would generate a rapid and durable neutralizing antibody response are desirable, a ...
Yeji Lee, A. Sette, A. Grifoni
semanticscholar +2 more sources
A study on the codon usage bias of arenavirus common genes [PDF]
Frontiers in MicrobiologyIntroductionThe Arenaviridae family consists of the genera Mammarenavirus, Reptarenavirus, Hartmanivirus, Antennavirus and Innmovirus. The codon usage bias between the different genera has not yet been studied comparatively.MethodsWe retrieved the ...
Pablo Daniel Thomas +3 more
doaj +2 more sources
Detection and Genomic Characterization of Novel Mammarenavirus in European Hedgehogs, Italy [PDF]
Emerging Infectious DiseasesMammarenaviruses are noteworthy zoonotic pathogens, and the main reservoirs are rodent species. We report the detection of a novel mammarenavirus in 6/183 (3.3%) in necropsied European hedgehogs (Erinaceus europaeus) collected in Italy. The whole-genome
Barbara Di Martino +10 more
doaj +2 more sources
Retrospective Screening for Zoonotic Viruses in Encephalitis Cases in Austria, 2019–2023, Reveals Infection with Lymphocytic Choriomeningitis Virus but Not with Rustrela Virus or Tahyna Virus [PDF]
VirusesZoonotic viruses may be neglected as etiologies of meningoencephalitis in humans. We performed retrospective testing of cerebrospinal fluid from encephalitis cases in biobank material for three zoonotic or potentially zoonotic viruses: rustrela virus ...
Jeremy V. Camp +3 more
doaj +2 more sources
Virome landscape of wild rodents and shrews in Central China [PDF]
MicrobiomeBackground Wild rodents and shrews serve as vital sentinel species for monitoring zoonotic viruses due to their close interaction with human environments and role as natural reservoirs for diverse viral pathogens.
Nailou Zhang +11 more
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bioRxiv, 2019 Arenaviral infections often resulting in lethal Hemorrhagic Fevers (HF) affect primarily African and South American regions. To date, there is no FDA-approved licensed vaccine against arenaviruses and treatments have been limited to supportive therapies.
Kazi Faizul Azim +6 more
semanticscholar +2 more sources