Results 41 to 50 of about 2,974 (161)
Heliyon, 2021 Arenaviral infections often result lethal hemorrhagic fevers, affecting primarily in African and South American regions. To date, there is no FDA-approved licensed vaccine against arenaviruses and treatments have been limited to supportive therapy. Hence,
Kazi Faizul Azim +6 more
doaj +1 more source
Protein Science, Volume 34, Issue 12, December 2025.Abstract Human transferrin receptor 1 (TfR) is essential for cellular iron homeostasis by internalizing the iron carrier proteins transferrin and ferritin. It is also an entry point for various pathogens, such as South American hemorrhagic fever caused by arenaviruses and the malaria parasite Plasmodium vivax, which utilize TfR to gain access to cells.
Anuthariq Alikkam Veetil +5 more
wiley +1 more source
Emerging Infectious Diseases, 2002 Thirty-four rodents captured in southern California were studied to increase our knowledge of the arenaviruses indigenous to the western United States.
Charles F. Fulhorst +6 more
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Virulence, 2023 Mammarenaviruses, a genus of the family Arenaviridae, are capable of infecting mammals and are primarily found in rodent reservoirs worldwide. Mammarenaviruses can be transmitted to humans through contact with infected rodents, and though infection is ...
Brigitte Flannery +2 more
doaj +1 more source
Journal of Cellular and Molecular Medicine, Volume 29, Issue 20, October 2025.ABSTRACT Lassa virus (LASV) remains a persistent threat to public health, and to combat this, various therapeutics have been developed, but their effectiveness is limited due to the virus's strain variability. Therefore, mutation‐based reverse vaccinology approaches were implemented to formulate an epitope‐based vaccine against the LASV, considering ...
Saurav Kumar Mishra +7 more
wiley +1 more source
Single Nucleoprotein Residue Modulates Arenavirus Replication Complex Formation
mBio, 2015 The Arenaviridae are enveloped, negative-sense RNA viruses with several family members that cause hemorrhagic fevers. This work provides immunofluorescence evidence that, unlike those of New World arenaviruses, the replication and transcription complexes
Kristeene A. Knopp +3 more
doaj +1 more source
The Biological Characteristics and Mouse Model of Lassa Virus From the First Imported Case in China
MedComm, Volume 6, Issue 8, August 2025.This is the first case of Lassa fever being introduced to China. A strain of the Lineage IV LASV was successfully isolated, and genomic and mutation analysis were conducted. Infection models were constructed using BALB/c, C57BL/6, and AG129 mice, which were successfully established.
Yanan Zhou +25 more
wiley +1 more source
Virus Arenaviridae y Fiebres Hemorrágicas: Una Revisión
Revista Científica de Enfermería UNITEPC, 2023 Introducción: Los arenavirus, pertenecientes a la familia Arenaviridae, pueden provocar fiebre hemorrágica, una enfermedad grave. Debido a brotes esporádicos y la falta de conocimiento en áreas críticas, la investigación de estos virus es esencial para mejorar la detección, prevención y respuesta a estas amenazas para la salud pública, desarrollando ...
Juan de Dios Mogro Lujan +1 more
openaire +1 more source
Lymphocytic Choriomeningitis in Michigan
Emerging Infectious Diseases, 2006 We summarize the first reported case of acquired lymphocytic choriomeningitis virus (LCMV) infection in Michigan to be investigated by public health authorities and provide evidence of the focal nature of LCMV infection in domestic rodents.
Erik S. Foster +6 more
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Viral hemorrhagic fevers - a recurrent public health threat
Health Problems of Civilization, 2021 Viral hemorrhagic fevers (VHFs) caused by viruses are severe infectious diseases that lead to serious disturbances of the body’s homeostasis, in most cases accompanied by symptoms of hemorrhagic diathesis.
Marcin Weiner, Karolina Tarasiuk
doaj +1 more source