Results 51 to 60 of about 4,641 (195)

Selection and Characterization of Single-Domain Antibodies for Detection of Lassa Nucleoprotein

open access: yesAntibodies, 2020
Lassa virus is the etiologic agent of Lassa fever, an acute and often fatal illness endemic to West Africa. It is important to develop new reagents applicable either for the specific diagnosis or as improved therapeutics for the treatment of Lassa fever.
George P. Anderson   +3 more
doaj   +1 more source

Recent Discoveries of Novel Mammarenaviruses Infecting Humans and Other Mammals in Asia and Southeast Asia

open access: yesVirulence, 2023
Mammarenaviruses, a genus of the family Arenaviridae, are capable of infecting mammals and are primarily found in rodent reservoirs worldwide. Mammarenaviruses can be transmitted to humans through contact with infected rodents, and though infection is ...
Brigitte Flannery   +2 more
doaj   +1 more source

False positives complicate ancient pathogen identifications using high-throughput shotgun sequencing [PDF]

open access: yes, 2014
Background: Identification of historic pathogens is challenging since false positives and negatives are a serious risk. Environmental non-pathogenic contaminants are ubiquitous.
Campana, Michael G   +3 more
core   +3 more sources

Pathogenesis of Lassa Fever

open access: yesViruses, 2012
Lassa virus, an Old World arenavirus (family Arenaviridae), is the etiological agent of Lassa fever, a severe human disease that is reported in more than 100,000 patients annually in the endemic regions of West Africa with mortality rates for ...
David H. Walker, Nadezhda E. Yun
doaj   +1 more source

Strategic Preparedness of Broad‐Spectrum Antivirals for Rapid Response Towards Next Pandemics

open access: yesSmall Science, Volume 6, Issue 1, January 2026.
Nanoengineered broad‐spectrum antivirals (BSAs) represent a transformative approach to pandemic preparedness. Unlike virus‐specific drugs requiring separate development, BSAs act across multiple viral families through nanoengineering strategies that enhance solubility, bioavailability, and host‐targeted activity.
Sanoj Rejinold N   +2 more
wiley   +1 more source

Bear Canyon Virus: An Arenavirus Naturally Associated with the California Mouse (Peromyscus californicus)

open access: yesEmerging Infectious Diseases, 2002
Thirty-four rodents captured in southern California were studied to increase our knowledge of the arenaviruses indigenous to the western United States.
Charles F. Fulhorst   +6 more
doaj   +1 more source

Viral discovery and diversity in trypanosomatid protozoa with a focus on relatives of the human parasite Leishmania. [PDF]

open access: yes, 2017
Knowledge of viral diversity is expanding greatly, but many lineages remain underexplored. We surveyed RNA viruses in 52 cultured monoxenous relatives of the human parasite <i>Leishmania</i> ( <i>Crithidia</i> and <i> ...
Akopyants, N.S.   +19 more
core   +1 more source

Surveillance of Zoonotic Pathogens in Small Mammals Across Forests With Different Levels of Anthropization in Eastern France

open access: yesTransboundary and Emerging Diseases, Volume 2026, Issue 1, 2026.
The emergence of infectious diseases associated with land‐use changes is well‐documented. However, the presence and dynamics of zoonotic pathogens in small mammals within European forests, whether from rural development or urban greening, remain underexplored.
Marie Bouilloud   +15 more
wiley   +1 more source

LUJO HEMORRHAGIC FEVER

open access: yesВопросы вирусологии, 2017
Lujo hemorrhagic fever (LHF) is a viral disease accompanied with fever, headache, vomiting, diarrhea, arthralgia, myalgia and numerous signs of hemorrhagic syndrome. LHF causes a clinical syndrome remarkably similar to Lassa hemorrhagic fever.
T. E. Sizikova   +3 more
doaj   +1 more source

The ovarian cancer oncobiome. [PDF]

open access: yes, 2017
Humans and other mammals are colonized by microbial agents across the kingdom which can represent a unique microbiome pattern. Dysbiosis of the microbiome has been associated with pathology including cancer.
Alwine, J.C.   +7 more
core   +2 more sources

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