Results 71 to 80 of about 2,974 (161)

Transcriptional analysis of antiviral small molecule therapeutics as agonists of the RLR pathway

Genomics Data, 2016
The recognition of pathogen associated molecular patterns (PAMPs) by pattern recognition receptors (PRR) during viral infection initiates the induction of antiviral signaling pathways, including activation of the Interferon Regulator Factor 3 (IRF3).
R.R. Green, C. Wilkins, S. Pattabhi, R. Dong, Y. Loo, M. Gale, Jr   +5 more
doaj   +1 more source

Cellular endosomal potassium ion flux regulates arenavirus uncoating during virus entry

mBio
Lymphocytic choriomeningitis virus (LCMV) is an enveloped and segmented negative-sense RNA virus classified within the Arenaviridae family of the Bunyavirales order.
Amelia B. Shaw, Hiu Nam Tse, Owen Byford, Grace Plahe, Alex Moon-Walker, Samantha E. Hover, Erica Ollmann Saphire, Sean P. J. Whelan, Jamel Mankouri, Juan Fontana, John N. Barr   +10 more
doaj   +1 more source

Systems immunology of transcriptional responses to viral infection identifies conserved antiviral pathways across macaques and humans

Cell Reports
Summary: Viral pandemics and epidemics pose a significant global threat. While macaque models of viral disease are routinely used, it remains unclear how conserved antiviral responses are between macaques and humans.
Kalani Ratnasiri, Hong Zheng, Jiaying Toh, Zhiyuan Yao, Veronica Duran, Michele Donato, Mario Roederer, Megha Kamath, John-Paul M. Todd, Matthew Gagne, Kathryn E. Foulds, Joseph R. Francica, Kizzmekia S. Corbett, Daniel C. Douek, Robert A. Seder, Shirit Einav, Catherine A. Blish, Purvesh Khatri   +17 more
doaj   +1 more source

LASSA FEVER – UN PEACEKEEPERS’ NIGHTMARE IN WEST AFRICA

Pakistan Armed Forces Medical Journal, 2018
Lassa fever is a viral haemorrhagic fever caused by Lassa virus belonging to Arenaviridae family and is endemic in West African countries of Sierra Leone, Liberia, Guinea and Nigeria.
Irfan Ali Mirza, Muhammad Azmat Khan, Abdul Hakim   +2 more
doaj  

Progress toward the development of Lassa vaccines

Expert Review of Vaccines
Hinh Ly
doaj   +1 more source

When zoonosis mimics autoimmunity: arenavirus spillover, gut dysbiosis, and the case for community-level early warning systems. [PDF]

Ann Med Surg (Lond)
Sanan A, Tanveer M, Batool ST, Sadat SH.
europepmc   +1 more source

A Roadmap Towards the Identification and Validation of Conserved T Cell Epitope Regions in Viral Pathogen Families with Pandemic Potential. [PDF]

Curr Pharm Biotechnol
Grifoni A, Sidney J, Weiskopf D, Scheuermann RH, Sette A.   +4 more
europepmc   +1 more source

Viral metagenome characterization reveals species-specific virome profiles in Triatominae populations from the southern United States. [PDF]

PLoS Negl Trop Dis
Habib I, Hernandez-Valencia JC, Martinu J, Novakova E.   +3 more
europepmc   +1 more source

Viral zoonoses assessment in invasive rodent species from São Tomé and Príncipe. [PDF]

PLoS One
Almeida T, Matos MC, Velarde-Garcéz DA, Mata VA, Martins M, Neves C, Beja P, Lopes AM, Abrantes J.   +8 more
europepmc   +1 more source

Ebola Virus Disease: Uniquely Challenging Among the Viral Hemorrhagic Fevers. [PDF]

Open Forum Infect Dis
Matson MJ, Chertow DS, Munster VJ.
europepmc   +1 more source