Results 91 to 100 of about 4,641 (195)
, 2008 In the aftermath of the September 11, 2001 attacks and the subsequent mail-borne anthrax attack of October 2001, it has become dear that health care providers may be called upon to respond to victims of terrorism. Biological terrorism (BT), in particular,
Centers for Disease Control and Prevention +4 more
core +2 more sources
Enhanced methods for unbiased deep sequencing of Lassa and Ebola RNA viruses from clinical and biological samples [PDF]
, 2015 We have developed a robust RNA sequencing method for generating complete de novo assemblies with intra-host variant calls of Lassa and Ebola virus genomes in clinical and biological samples.
Andersen, Kristian G +26 more
core +1 more source
Transcriptional analysis of antiviral small molecule therapeutics as agonists of the RLR pathway
Genomics Data, 2016 The recognition of pathogen associated molecular patterns (PAMPs) by pattern recognition receptors (PRR) during viral infection initiates the induction of antiviral signaling pathways, including activation of the Interferon Regulator Factor 3 (IRF3).
R.R. Green +5 more
doaj +1 more source
Extreme Genetic Diversity among Pirital Virus (Arenaviridae) Isolates from Western Venezuela
Virology, 2001 Pirital-like virus isolates from rodents collected in a variety of habitats within a six-state area of central Venezuela were analyzed genetically by amplifying a portion of the nucleocapsid protein gene using RT-PCR. Comparisons of the sequences from 30 selected Pirital-like virus isolates demonstrated up to 26% divergence in nucleotide sequences and ...
Weaver, Scott C. +12 more
openaire +2 more sources
Host Cell Factors as Antiviral Targets in Arenavirus Infection
Viruses, 2012 Among the members of the Arenaviridae family, Lassa virus and Junin virus generate periodic annual outbreaks of severe human hemorrhagic fever (HF) in endemic areas of West Africa and Argentina, respectively.
Elsa B. Damonte +6 more
doaj +1 more source
Arenavirus Budding: A Common Pathway with Mechanistic Differences
Viruses, 2013 The Arenaviridae is a diverse and growing family of viruses that includes several agents responsible for important human diseases. Despite the importance of this family for public health, particularly in Africa and South America, much of its biology ...
Svenja Wolff +2 more
doaj +1 more source
The Role of Platelets in Viral Hemorrhagic Fevers [PDF]
, 2013 Arenaviridae, Bunyaviridae, Filoviridae and Flaviviridae are all RNA viruses that can induce a coagulopathy in infected patients. While there is a paucity of information on the cause of this coagulopathy, these viruses all produce a severe ...
Cox, Dermot +2 more
core +1 more source
Cellular endosomal potassium ion flux regulates arenavirus uncoating during virus entry
mBioLymphocytic choriomeningitis virus (LCMV) is an enveloped and segmented negative-sense RNA virus classified within the Arenaviridae family of the Bunyavirales order.
Amelia B. Shaw +10 more
doaj +1 more source
Boid inclusion body disease : the enigma unraveled? [PDF]
, 2019 Boid inclusion body disease is a worldwide occurring disease in boas and pythons. The identity of the etiological agent of the disease remained elusive for several decades.
Hellebuyck, Tom, Simard, Jules
core
Cell ReportsSummary: Viral pandemics and epidemics pose a significant global threat. While macaque models of viral disease are routinely used, it remains unclear how conserved antiviral responses are between macaques and humans.
Kalani Ratnasiri +17 more
doaj +1 more source