Results 61 to 70 of about 4,641 (195)

Arenaviridae exoribonuclease presents genomic RNA edition capacity [PDF]

, 2019
AbstractThe Arenaviridae is a large family of viruses causing both acute and persistent infections and causing significant public health concerns in afflicted regions. A “trademark” of infection is the quick and efficient immuno-suppression mediated in part by a 3’-5’ RNA exonuclease domain (ExoN) of the Nucleoprotein (NP).
Yekwa, Elsie, Aphibanthammakit, Chutima, Carnec, Xavier, Coutard, Bruno, Picard, Caroline, Canard, Bruno, Baize, Sylvain, Ferron, François   +7 more
openaire   +1 more source

Unveiling Novel Viral Diversity, Biogeography, and Host Networks in Wildlife Through High‐Throughput Sequencing Data Mining

Advanced Science, Volume 12, Issue 46, December 11, 2025.
Analysis of 57 536 high‐throughput sequencing datasets uncovers a vast, hidden world of viruses in wildlife. The researchers reveal significant geographic and host‐specific patterns of viruses, and their surprising cross‐species transmissions, such as avian flu viruses infecting goats.
Hai Wang, Yafei Meng, Xiaoyuan Chen, Xinyuan Cui, Qian Zuo, Na Han, Xianghui Liang, Xuejuan Shen, Caiwu Li, Desheng Li, Fumin Wang, Liangping He, Rujian Chen, Xingbang Lu, Wenjie You, Aiping Wu, Rui‐Ai Chen, Wu Chen, Chan Ding, Yongyi Shen   +19 more
wiley   +1 more source

Viral hemorrhagic fevers - a recurrent public health threat

Health Problems of Civilization, 2021
Viral hemorrhagic fevers (VHFs) caused by viruses are severe infectious diseases that lead to serious disturbances of the body’s homeostasis, in most cases accompanied by symptoms of hemorrhagic diathesis.
Marcin Weiner, Karolina Tarasiuk
doaj   +1 more source

A Mutation‐Based Reverse Vaccinology Approach Considering Variability in Epitopes to Combat Multi‐Strains: A Study Using Glycoprotein of LASV

Journal of Cellular and Molecular Medicine, Volume 29, Issue 20, October 2025.
ABSTRACT Lassa virus (LASV) remains a persistent threat to public health, and to combat this, various therapeutics have been developed, but their effectiveness is limited due to the virus's strain variability. Therefore, mutation‐based reverse vaccinology approaches were implemented to formulate an epitope‐based vaccine against the LASV, considering ...
Saurav Kumar Mishra, Rajesh B. Patil, Amdola Tshering Sherpa, Mohammad Borhan Uddin, Md. Harun‐Or‐Rashid, Muniruddin Ahmed, Turki M. Dawoud, John J. Georrge   +7 more
wiley   +1 more source

Single Nucleoprotein Residue Modulates Arenavirus Replication Complex Formation

mBio, 2015
The Arenaviridae are enveloped, negative-sense RNA viruses with several family members that cause hemorrhagic fevers. This work provides immunofluorescence evidence that, unlike those of New World arenaviruses, the replication and transcription complexes
Kristeene A. Knopp, Tuan Ngo, Paul D. Gershon, Michael J. Buchmeier   +3 more
doaj   +1 more source

The Biological Characteristics and Mouse Model of Lassa Virus From the First Imported Case in China

MedComm, Volume 6, Issue 8, August 2025.
This is the first case of Lassa fever being introduced to China. A strain of the Lineage IV LASV was successfully isolated, and genomic and mutation analysis were conducted. Infection models were constructed using BALB/c, C57BL/6, and AG129 mice, which were successfully established.
Yanan Zhou, Junbin Wang, Ranran Cao, Yun Yang, Yuliang Feng, Cong Tang, Hao Yang, Qing Huang, Wenhai Yu, Haixuan Wang, Jiandong Shi, Kaiyun Ding, Longhai Yuan, Qing Dai, Xingping Zhao, Haiyan Li, Mengli Yang, Fangyu Luo, Fanli Zhu, Yong Zhang, Daoju Wu, Xiaorong Yang, Shuaiyao Lu, Qiangming Sun, Li Zhang, Youchun Wang   +25 more
wiley   +1 more source

Lymphocytic Choriomeningitis in Michigan

Emerging Infectious Diseases, 2006
We summarize the first reported case of acquired lymphocytic choriomeningitis virus (LCMV) infection in Michigan to be investigated by public health authorities and provide evidence of the focal nature of LCMV infection in domestic rodents.
Erik S. Foster, Kimberly Signs, David R. Marks, Hema Kapoor, Margaret Casey, Mary Grace Stobierski, Edward D Walker   +6 more
doaj   +1 more source

Production of CXC and CC chemokines by human antigen-presenting cells in response to Lassa virus or closely related immunogenic viruses, and in cynomolgus monkeys with lassa fever. [PDF]

, 2014
International audienceThe pathogenesis of Lassa fever (LF), a hemorrhagic fever endemic to West Africa, remains unclear. We previously compared Lassa virus (LASV) with its genetically close, but nonpathogenic homolog Mopeia virus (MOPV) and demonstrated ...
A Mantovani, A Wack, B Moser, C Pythoud, C-L Lin, D Cook, D Pannetier, D Pannetier, D Whiting, DD Pinschewer, DD Taub, DD Taub, DD Taub, Delphine Pannetier, DH Walker, DH Walker, F Castellino, H Sung Jung, H Wulff, IS Lukashevich, J ter Meulen, J ter Meulen, JB McCormick, JB McCormick, JE Christensen, JF Foley, JH Dufour, JR Groom, KM Hastie, KM Johnson, L Hensley, L Martinez-Sobrido, L Martinez-Sobrido, LL Xu, M Habjan, M Inngjerdingen, M Liu, M Loetscher, M Macal, M Perez, M Russier, M-F Hsieh, Marion Russier, MD Bowen, MM Djavani, MP Kiley, N Sogoba, O Lenz, R Lande, S Baize, S Baize, S Baize, S Deshmane, S Günther, S Mahanty, S Mahanty, S Malhotra, SL Ruo, Stéphanie Reynard, Sylvain Baize, T Strecker, Thomas Geisbert, TI Cornu, TJ Schall, W Cao, WWSI Rodrigo, X Carnec, X Qi, Xavier Carnec   +68 more
core   +5 more sources

A novel mammarenavirus (family Arenaviridae) in hedgehogs (Erinaceus roumanicus) in Europe

Archives of Virology, 2023
AbstractIn this study, a novel mammarenavirus (family Arenaviridae) was identified in a hedgehog (family Erinaceidae) in Hungary and genetically characterized. Mecsek Mountains virus (MEMV, OP191655, OP191656) was detected in nine (45%) out of 20 faecal specimens collected from a Northern white-breasted hedgehog (Erinaceus roumanicus).
Gábor Reuter, Ákos Boros, Károly Takáts, Róbert Mátics, Péter Pankovics   +4 more
openaire   +2 more sources

Marburg Virus Disease: A Narrative Review

Health Science Reports, Volume 8, Issue 5, May 2025.
ABSTRACT Background and Aims Given the recent deadly outbreaks of the Marburg virus (MARV), in early 2023 in Tanzania and Equatorial Guinea, and the most recent one in Rwanda in 2024, there has been renewed attention across Africa on the threat posed by the re‐emergence of MARV as a growing concern for public health.
Arash Letafati, Somayeh Sadat Hosseini Fakhr, Ali Qaraee Najafabadi, Negin Karami, Hassan Karami   +4 more
wiley   +1 more source