Results 81 to 90 of about 8,211 (209)

The Biological Characteristics and Mouse Model of Lassa Virus From the First Imported Case in China

MedComm, Volume 6, Issue 8, August 2025.
This is the first case of Lassa fever being introduced to China. A strain of the Lineage IV LASV was successfully isolated, and genomic and mutation analysis were conducted. Infection models were constructed using BALB/c, C57BL/6, and AG129 mice, which were successfully established.
Yanan Zhou, Junbin Wang, Ranran Cao, Yun Yang, Yuliang Feng, Cong Tang, Hao Yang, Qing Huang, Wenhai Yu, Haixuan Wang, Jiandong Shi, Kaiyun Ding, Longhai Yuan, Qing Dai, Xingping Zhao, Haiyan Li, Mengli Yang, Fangyu Luo, Fanli Zhu, Yong Zhang, Daoju Wu, Xiaorong Yang, Shuaiyao Lu, Qiangming Sun, Li Zhang, Youchun Wang   +25 more
wiley   +1 more source

Phylogeny of the genus Arenavirus

Current Opinion in Microbiology, 2008
The family Arenaviridae consists of a unique genus (Arenavirus) that currently comprises 22 viral species, as recognized by the International Committee for Taxonomy of Viruses. Seven newly discovered represent putative new species. Here, our aims were to provide the most comprehensive phylogenetic analysis of members and putative members of the family ...
Charrel, R. N., /Lamballerie de, Xavier, Emonet, S.   +2 more
openaire   +3 more sources

Co-infecting Reptarenaviruses Can Be Vertically Transmitted in Boa Constrictor [PDF]

, 2017
Boid inclusion body disease (BIBD) is an often fatal disease affecting mainly constrictor snakes. BIBD has been associated with infection, and more recently with coinfection, by various reptarenavirus species (family Arenaviridae). Thus far BIBD has only
Hepojoki, Jussi, Hetzel, Udo, Keller, Saskia, Kipar, Anja, Korzyukov, Yegor, Sironen, Tarja, Vapalahti, Olli   +6 more
core   +2 more sources

Evaluating the Potential Adverse Effects of Favipiravir on Biochemical, Histopathological, and Spermatological Parameters in Male Rats' Testicular Tissue

Journal of Biochemical and Molecular Toxicology, Volume 39, Issue 6, June 2025.
ABSTRACT Favipiravir is a selective RNA polymerase inhibitor and a broad‐spectrum antiviral drug. Favipiravir reduces cell proliferation by inhibiting RNA transcription, particularly in rapidly proliferating cells such as spermatogonia. The aim of this study was to investigate the effects and mechanism of action of favipiravir (T‐705) on sperm quality ...
Ali Doğan Ömür, Gamze Uçak, Adem Kara, Elif Erbaş, Serkan Ali Akarsu, Seçkin Özkanlar, Nevra Aydemir Celep   +6 more
wiley   +1 more source

Small-Molecule Probes Targeting the Viral PPxY-Host Nedd4 Interface Block Egress of a Broad Range of RNA Viruses. [PDF]

, 2014
Budding of filoviruses, arenaviruses, and rhabdoviruses is facilitated by subversion of host proteins, such as Nedd4 E3 ubiquitin ligase, by viral PPxY late (L) budding domains expressed within the matrix proteins of these RNA viruses.
Davis, Benjamin, Freedman, Bruce D, Han, Ziying, Harty, Ronald N, Lee, Michael S, Liu, Yuliang, Lu, Jianhong, Olson, Mark A, Reitz, Allen B, Ruthel, Gordon, Schnell, Matthias J, Wrobel, Jay E   +11 more
core   +2 more sources

Preparedness of Emergency Room Nurses for Bioterrorism Based on the Health Belief Model: A Multicenter Qualitative Study

International Nursing Review, Volume 72, Issue 2, June 2025.
ABSTRACT Aim To explore emergency room nurses’ perceptions of preparedness for bioterrorism. Introduction In the context of evolving global security threats, including wars, terrorism, and emerging infectious diseases, it is critical to evaluate the bioterrorism response competencies of emergency room nurses and identify strategies to enhance their ...
Mi‐Kyeong Jeon, Yujeong Kim
wiley   +1 more source

The origin and prevention of pandemics. [PDF]

, 2010
Despite the fact that most emerging diseases stem from the transmission of pathogenic agents from animals to humans, the factors that mediate this process are still ill defined.
Djoko, Cyrille F, Fair, Joseph N, Lebreton, Matthew, Pike, Brian L, Rimoin, Anne W, Saylors, Karen E, Tamoufe, Ubald, Wolfe, Nathan D   +7 more
core   +1 more source

Therapeutic options for human papillomavirus‐positive tonsil and base of tongue cancer

Journal of Internal Medicine, Volume 297, Issue 6, Page 608-629, June 2025.
Abstract The incidences of human papillomavirus‐positive (HPV+) tonsillar and base tongue squamous cell carcinomas (TSCC and BOTSCC) have increased in recent decades. Notably, HPV+ TSCC and BOTSCC have a significantly better prognosis than their HPV‐negative counterparts when treated with current surgical options, radiotherapy, or intensified ...
Mark Zupancic, Ourania N. Kostopoulou, Linda Marklund, Tina Dalianis   +3 more
wiley   +1 more source

Silver Nanoparticle‐Mediated Antiviral Efficacy against Enveloped Viruses: A Comprehensive Review

Global Challenges, Volume 9, Issue 5, May 2025.
Silver nanoparticles (AgNPs) exhibit broad‐spectrum antiviral activity by targeting key viral structures and processes. They disrupt viral envelopes, compromising integrity, and bind to nucleocapsids, impairing viral replication. AgNPs also inhibit glycoprotein interactions, preventing viral attachment and entry into host cells.
Ekaterine Mosidze, Gianluigi Franci, Federica Dell'Annunziata, Nicoletta Capuano, Marica Colella, Flora Salzano, Massimiliano Galdiero, Aliosha Bakuridze, Veronica Folliero   +8 more
wiley   +1 more source

Visualization of Double-Stranded RNA Colocalizing With Pattern Recognition Receptors in Arenavirus Infected Cells

Frontiers in Cellular and Infection Microbiology, 2018
An important step in the initiation of the innate immune response to virus infection is the recognition of non-self, viral RNA, including double-stranded RNA (dsRNA), by cytoplasmic pattern recognition receptors (PRRs).
Elizabeth J. Mateer, Slobodan Paessler, Cheng Huang   +2 more
doaj   +1 more source