Results 71 to 80 of about 4,888 (173)

Visualization of Double-Stranded RNA Colocalizing With Pattern Recognition Receptors in Arenavirus Infected Cells

Frontiers in Cellular and Infection Microbiology, 2018
An important step in the initiation of the innate immune response to virus infection is the recognition of non-self, viral RNA, including double-stranded RNA (dsRNA), by cytoplasmic pattern recognition receptors (PRRs).
Elizabeth J. Mateer, Slobodan Paessler, Cheng Huang   +2 more
doaj   +1 more source

Therapeutic options for human papillomavirus‐positive tonsil and base of tongue cancer

Journal of Internal Medicine, Volume 297, Issue 6, Page 608-629, June 2025.
Abstract The incidences of human papillomavirus‐positive (HPV+) tonsillar and base tongue squamous cell carcinomas (TSCC and BOTSCC) have increased in recent decades. Notably, HPV+ TSCC and BOTSCC have a significantly better prognosis than their HPV‐negative counterparts when treated with current surgical options, radiotherapy, or intensified ...
Mark Zupancic, Ourania N. Kostopoulou, Linda Marklund, Tina Dalianis   +3 more
wiley   +1 more source

Silver Nanoparticle‐Mediated Antiviral Efficacy against Enveloped Viruses: A Comprehensive Review

Global Challenges, Volume 9, Issue 5, May 2025.
Silver nanoparticles (AgNPs) exhibit broad‐spectrum antiviral activity by targeting key viral structures and processes. They disrupt viral envelopes, compromising integrity, and bind to nucleocapsids, impairing viral replication. AgNPs also inhibit glycoprotein interactions, preventing viral attachment and entry into host cells.
Ekaterine Mosidze, Gianluigi Franci, Federica Dell'Annunziata, Nicoletta Capuano, Marica Colella, Flora Salzano, Massimiliano Galdiero, Aliosha Bakuridze, Veronica Folliero   +8 more
wiley   +1 more source

ARENAVIRUS IN AMERICAN: A MINI-REVIEW

Revista ft
Arenaviral infections are frequent causes of acute diseases in humans.Some Arenavirus that can cause hemorrhagic fever in America are Junín virus in Argentina, Chapare Virus in Bolívia and Sabiá Vírus in Brazil [1]. Although each one has a distinct geographic distribution, they have common modes of transmission and the diseases associated with them [2].
Mello Aline Hevelin Walder de, Dezorze, Luiz Fernando, Souza, Michele de   +2 more
openaire   +1 more source

Arenavirus Infections

Revista MVZ Córdoba, 2017
Los síndromes infecciosos asociados a arenavirus en América del sur son cuatro: síndrome febril de origen viral; fiebres hemorrágicas con o sin compromiso neurológico; meningitis asépticas y meningo-encefalitis. Entre los Arenavirus del nuevo mundo, está el complejo Tacaribe donde se encuentran los virus: Junín (Argentina), Guanarito (Venezuela ...
Mattar V, Salim, Guzmán T, Camilo, Calderón R, Alfonso, González Tous, Marco   +3 more
openaire   +1 more source

Recombinant Lassa Virus Expressing Green Fluorescent Protein as a Tool for High-Throughput Drug Screens and Neutralizing Antibody Assays

Viruses, 2018
Lassa virus (LASV), a mammarenavirus, infects an estimated 100,000⁻300,000 individuals yearly in western Africa and frequently causes lethal disease.
Yíngyún Caì, Masaharu Iwasaki, Brett F. Beitzel, Shuīqìng Yú, Elena N. Postnikova, Beatrice Cubitt, Lisa Evans DeWald, Sheli R. Radoshitzky, Laura Bollinger, Peter B. Jahrling, Gustavo F. Palacios, Juan C. de la Torre, Jens H. Kuhn   +12 more
doaj   +1 more source

Junín Virus Pathogenesis and Virus Replication

Viruses, 2012
Junín virus, the etiological agent of Argentine hemorrhagic fever, causes significant morbidity and mortality. The virus is spread through the aerosolization of host rodent excreta and endemic to the humid pampas of Argentina.
Olga Kolokoltsova, Allan Brasier, Slobodan Paessler, Clarence Peters, Cheng Huang, Alexey Seregin, Ashley Grant   +6 more
doaj   +1 more source

Transcriptomic Signatures of Tacaribe Virus-Infected Jamaican Fruit Bats

mSphere, 2017
Tacaribe virus (TCRV) is a mammalian arenavirus that was first isolated from artibeus bats in the 1950s. Subsequent experimental infection of Jamaican fruit bats (Artibeus jamaicensis) caused a disease similar to that of naturally infected bats. Although
Diana L. Gerrard, Ann Hawkinson, Tyler Sherman, Cassandra M. Modahl, Gretchen Hume, Corey L. Campbell, Tony Schountz, Seth Frietze   +7 more
doaj   +1 more source

Structure and stabilization of the antigenic glycoprotein building blocks of the New World mammarenavirus spike complex

mBio
The spillover of New World (NW) arenaviruses from rodent reservoirs into human populations poses a continued risk to human health. NW arenaviruses present a glycoprotein (GP) complex on the envelope surface of the virion, which orchestrates host cell ...
Guido C. Paesen, Weng M. Ng, Simon Kimuda, Geoff Sutton, Katie J. Doores, Thomas A. Bowden   +5 more
doaj   +1 more source

Characterization of a STAT-1 Knockout Mouse Model for Machupo Virus Infection and Pathogenesis

Viruses
Machupo virus (MACV), a member of the Arenaviridae family and causative agent of Bolivian hemorrhagic fever, results in lethality rates of 25–35% in humans.
Stephanie R. Monticelli, Ana I. Kuehne, Russell R. Bakken, Susan R. Coyne, Kenise D. Lewis, Jo Lynne W. Raymond, Xiankun Zeng, Joshua B. Richardson, Zebulon Lapoint, Jennifer L. Williams, Christopher P. Stefan, Jeffrey R. Kugelman, Jeffrey W. Koehler, Andrew S. Herbert   +13 more
doaj   +1 more source