The small
AbstractThe small GTPase Arf1 plays critical roles in membrane traffic by initiating the recruitment of coat proteins and by modulating the activity of lipid‐modifying enzymes. Here, we report an unexpected but evolutionarily conserved role for Arf1 and the ArfGEF GBF1 at mitochondria.
Ackema, K. B. +9 more
openaire +4 more sources
Mouse hepatitis coronavirus RNA replication depends on GBF1-mediated ARF1 activation. [PDF]
Coronaviruses induce in infected cells the formation of double membrane vesicles, which are the sites of RNA replication. Not much is known about the formation of these vesicles, although recent observations indicate an important role for the endoplasmic
Monique H Verheije +7 more
doaj +1 more source
Measurement of the electron's electric dipole moment using YbF molecules: methods and data analysis
We recently reported a new measurement of the electron's electric dipole moment using YbF molecules [Nature 473, 493 (2011)]. Here, we give a more detailed description of the methods used to make this measurement, along with a fuller analysis of the data.
B E Sauer +21 more
core +1 more source
The tasiR‐ARF pathway in plants: origin, functions, and interplay of miR‐390, tasiRNAs and ARF3
Trans‐acting small interfering RNAs that silence a subset of Auxin Response Factors are crucial for plant growth, developmental timing, proper organ patterning, and coping with stress. Abstract Trans‐acting small interfering RNA (tasiRNAs) are a special type of endogenous small RNAs (sRNAs) found only in plants.
B. A. López‐Ruiz +4 more
wiley +1 more source
Modelling the influence of dimerisation sequence dissimilarities on the auxin signalling network [PDF]
International audienceBackground: Auxin is a major phytohormone involved in many developmental processes by controlling gene expression through a network of transcriptional regulators.
Guédon, Yann +4 more
core +5 more sources
Mechanobiological Dynamics‐Inspired Mechanomodulatory Biomaterials
Recent advances in biomaterial‐mediated mechanomodulation of stem cell fate, encompassing 2, 3, and 4D systems and their synergy with artificial intelligence is overviewed. By integrating knowledge from diverse fields, this review ultimately aims to inspire the design of smarter biomaterial systems that can accelerate the clinical translation of ...
Letao Yang +6 more
wiley +1 more source
The Sec7 N-terminal regulatory domains facilitate membrane-proximal activation of the Arf1 GTPase
The Golgi complex is the central sorting compartment of eukaryotic cells. Arf guanine nucleotide exchange factors (Arf-GEFs) regulate virtually all traffic through the Golgi by activating Arf GTPase trafficking pathways.
Brian C Richardson +3 more
doaj +1 more source
Hijacking of multiple phospholipid biosynthetic pathways and induction of membrane biogenesis by a picornaviral 3CD protein. [PDF]
RNA viruses induce specialized membranous structures for use in genome replication. These structures are often referred to as replication organelles (ROs). ROs exhibit distinct lipid composition relative to other cellular membranes.
Sravani Banerjee +10 more
doaj +1 more source
ARF1 contrôle la migration des cellules hautement invasives du cancer du sein via Rac1 [PDF]
Dans un contexte où la forte prévalence du cancer du sein chez les femmes demeure depuis plusieurs années un enjeu de société majeur, les nouvelles stratégies visant à réduire la mortalité associée à cette maladie sont le sujet de nombreuses recherches ...
Lewis-Saravalli, Sebastian
core
An alternative secretory pathway in the malaria parasite Plasmodium falciparum [PDF]
The malaria parasite P. falciparum invades human red blood cells (RBCs). During invasion a compartment surrounding the parasite, the so-called parasitophorous vacuole (PV), is formed. The parasite resides and develops within the PV, which protects the
Lingelbach, Klaus (Prof. Dr.) +1 more
core +1 more source

