Results 91 to 100 of about 7,868 (194)
The tasiR‐ARF pathway in plants: origin, functions, and interplay of miR‐390, tasiRNAs and ARF3
Plant Biology, Volume 28, Issue 2, Page 328-344, March 2026.Trans‐acting small interfering RNAs that silence a subset of Auxin Response Factors are crucial for plant growth, developmental timing, proper organ patterning, and coping with stress. Abstract Trans‐acting small interfering RNA (tasiRNAs) are a special type of endogenous small RNAs (sRNAs) found only in plants.
B. A. López‐Ruiz +4 more
wiley +1 more source
A novel physiological role for ARF1 in the formation of bidirectional tubules from the Golgi [PDF]
, 2017 Capitalizing on CRISPR/Cas9 gene-editing techniques and super-resolution nanoscopy, we explore the role of the small GTPase ARF1 in mediating transport steps at the Golgi.
Bewersdorf, Joerg +38 more
core +1 more source
The Sec7 N-terminal regulatory domains facilitate membrane-proximal activation of the Arf1 GTPase
eLife, 2016 The Golgi complex is the central sorting compartment of eukaryotic cells. Arf guanine nucleotide exchange factors (Arf-GEFs) regulate virtually all traffic through the Golgi by activating Arf GTPase trafficking pathways.
Brian C Richardson +3 more
doaj +1 more source
Mechanobiological Dynamics‐Inspired Mechanomodulatory Biomaterials
Advanced Science, Volume 13, Issue 4, 19 January 2026.Recent advances in biomaterial‐mediated mechanomodulation of stem cell fate, encompassing 2, 3, and 4D systems and their synergy with artificial intelligence is overviewed. By integrating knowledge from diverse fields, this review ultimately aims to inspire the design of smarter biomaterial systems that can accelerate the clinical translation of ...
Letao Yang +6 more
wiley +1 more source
Mechanical Cues Regulate Cargo Sorting and Export at the Golgi
Advanced Science, Volume 13, Issue 1, 5 January 2026.A pathway is identified linking extracellular matrix stiffness to secretion via Src–FAK–AMPK–GBF1 signaling. Golgi‐localized GBF1 acts as a mechanotransducer whose phosphorylation controls post‐Golgi cargo sorting toward secretion or lysosomal degradation.
Greta Serafino +21 more
wiley +1 more source
Relative positions of N-terminal extension residues within the non-myristoylated WT Arf1•GDP and [L8K]Arf1•G3D crystal structures.
R. Andrew Byrd (2463943) +10 more
core +1 more source
Structural Basis for Recruitment and Activation of the AP-1 Clathrin Adaptor Complex by Arf1
, 2013 SummaryAP-1 is a clathrin adaptor complex that sorts cargo between the trans-Golgi network and endosomes. AP-1 recruitment to these compartments requires Arf1-GTP.
Ren, Xuefeng +4 more
core +1 more source
eLife, 2017 COPI coated vesicles mediate trafficking within the Golgi apparatus and between the Golgi and the endoplasmic reticulum. Assembly of a COPI coated vesicle is initiated by the small GTPase Arf1 that recruits the coatomer complex to the membrane ...
Svetlana O Dodonova +8 more
doaj +1 more source
The Small GTPase Arf1 Modulates Arp2/3-Mediated Actin Polymerization via PICK1 to Regulate Synaptic Plasticity [PDF]
, 2013 Inhibition of Arp2/3-mediated actin polymerization by PICK1 is a central mechanism to AMPA receptor (AMPAR) internalization and long-term depression (LTD), although the signaling pathways that modulate this process in response to NMDA receptor (NMDAR ...
Antoniou, Anna +14 more
core +1 more source
Kaohsiung Journal of Medical Sciences, 2020 miR‐744‐5p has been demonstrated to play an important role in cancer progression. However, the functions of miR‐744‐5p in epithelial ovarian cancer (EOC) are not well clarified.
Lai‐Gang Zhao +3 more
doaj +1 more source