Results 71 to 80 of about 7,868 (194)
Analysis of endocytic pathways in Drosophila cells reveals a conserved role for GBF1 in internalization via GEECs. [PDF]
PLoS ONE, 2009 In mammalian cells, endocytosis of the fluid phase and glycosylphosphatidylinositol-anchored proteins (GPI-APs) forms GEECs (GPI-AP enriched early endosomal compartments) via an Arf1- and Cdc42-mediated, dynamin independent mechanism.
Gagan D Gupta +5 more
doaj +1 more source
Emerging Roles of Adenosine Metabolism in Astrocytes During Brain Injury
CNS Neuroscience &Therapeutics, Volume 32, Issue 5, May 2026.Adenosine, as a key metabolic and neurotransmitter in the brain, has become an important therapeutic target for improving the efficacy of immunotherapy for stroke. However, gaps in knowledge about its metabolic pathways have become a key factor limiting its clinical translation.
Shu Zhu +4 more
wiley +1 more source
Advanced Science, Volume 13, Issue 24, 27 April 2026.In wild‐type cells, FIPV infection recruits CLTC to nsp3, facilitates DMV biogenesis and block autophagic flux to promote viral replication. CLTC knockout impairs autophagosome nucleation by reducing Beclin1–ATG14 complex expression. This disrupts the formation of autophagic precursor membranes, thereby preventing their hijacking by nsp3 for DMV ...
Juan Xu +9 more
wiley +1 more source
Architecture of the vimentin cytoskeleton is modified by perturbation of the GTPase ARF1 [PDF]
Journal of Cell Science, 2006 Intermediate filaments are required for proper membrane protein trafficking. However, it remains unclear whether perturbations in vesicular membrane transport result in changes in the architecture of the vimentin cytoskeleton. We find that treatment of cells with Brefeldin A, an inhibitor of specific stages of membrane transport, causes changes in the ...
Melanie L, Styers +2 more
openaire +2 more sources
Measurement of ARF6-CFP and ARF1-CFP Activation at Phagosomes
, 2013 FRET microscopic measurement of ARF6-CFP and ARF1-CFP activation during phagocytosis. (A, C, and E) Phase contrast and ED images of phagocytic events from macrophages co-expressing ARF6-CFP and YFP-NGAT, ARF1-CFP and YFP-NGAT, or ARF6-CFP and
Adam D Hoppe (57946) +2 more
core +1 more source
Scientific Reports, 2017 How multicellular organisms maintain immune homeostasis across various organs and cell types is an outstanding question in immune biology and cell signaling.
Rohan J. Khadilkar +6 more
doaj +1 more source
Energy of interaction between Arf1 and Mg.
, 2013 Interaction energy between Arf1 and Mg in the molecular dynamics simulations for the Mg-containing model complexes IIm1 and IIm2 (top and middle sets of lines, respectively) and for the reference Arf1-GDP-Mg system (1hur) seen at bottom, presented as a ...
Mériam Ben Hamida-Rebaï (367253) +1 more
core +1 more source
mBio, 2015 To establish intracellular infections, Salmonella bacteria trigger host cell membrane ruffling and invasion by subverting cellular Arf guanine nucleotide exchange factors (GEFs) that activate Arf1 and Arf6 GTPases by promoting GTP binding.
Anthony C. Davidson +4 more
doaj +1 more source
Drug Testing and Analysis, Volume 18, Issue 4, Page 581-602, April 2026.A two‐stage transcriptomic filter comparing rHuEPO, exercise and altitude responses reduced 153 candidate genes to 50 that were unaffected by physiological stimuli. These retained transcripts offer focused biomarker leads to strengthen antidoping detection of rHuEPO.
Daria Obratov +4 more
wiley +1 more source
The Role of ARF1 and Rab GTPases in Polarization of the Golgi Stack [PDF]
Traffic, 2005 The organization and sorting of proteins within the Golgi stack to establish and maintain its cis to trans polarization remains an enigma. The function of Golgi compartments involves coat assemblages that facilitate vesicle traffic, Rab‐tether‐SNAP receptor (SNARE) machineries that dictate membrane identity, as well as matrix components that maintain ...
Serguei I, Bannykh +3 more
openaire +2 more sources