Results 71 to 80 of about 50,915 (302)

Arginase activity is cell-associated.

, 2013
GL-1 cells were cultured for 24 hours in arginine-free (AF) or normal RPMI media plus/minus 10 U/ml Arginase. Arginase activity was then measured in filtered supernatant (A, B) or cell lysate (C, D) using a QuantiChrom Arginase Assay kit.
Barbara C. Rütgen (276709), Slobodan Tepic (276713), James W. Wells (276705), Milcah C. Scott (276708), Timothy D. O'Brien (276710), Christopher H. Evans (276706), Jaime F. Modiano (137112), Goran Cvetkovic (276712)   +7 more
core   +1 more source

Poly (ADP-Ribose) Polymerase 1 Mediated Arginase II Activation Is Responsible for Oxidized LDL-Induced Endothelial Dysfunction

Frontiers in Pharmacology, 2018
It is well known that arginase II leads to decreased synthesis of nitric oxide (NO) by competing with endothelial nitric oxide synthase (eNOS) for their same substrate L-arginine.
Qi Wang, Tong Zhao, Wei Zhang, Wenbin Yu, Bin Liu, Zhaoyang Wang, Wen Qiao, Qinghua Lu, Aihua Wang, Mingxiang Zhang, Mingxiang Zhang   +10 more
doaj   +1 more source

Arginase‐flotillin interaction brings arginase to red blood cell membrane [PDF]

FEBS Letters, 2006
Flotillin‐1 and arginase are both up‐regulated in red blood cell membrane of type 2 diabetic patients. For studying why the soluble arginase can bind to the membrane and whether such binding would modify arginase activity, the arginase1 and related proteins were cloned and expressed.
Jiang, Ming, Ding, Yu, Su, Yang, Hu, Xiaojian, Li, Jinying, Zhang, Zhihong   +5 more
openaire   +2 more sources

Mesenchymal Stromal Cell‐Based Cell–Drug Conjugates for the Treatment of Acute Liver Failure

Advanced Science, EarlyView.
Mesenchymal stromal cell (MSC)‐based cell‐drug conjugates are constructed by anchoring rosiglitazone‐loaded nanoparticles onto the MSC surface. Sustained rosiglitazone release enhances MSC proliferation and paracrine activity while promoting anti‐inflammatory macrophage polarization.
Tenghui Ye, Jiamin Wu, Zixin Wu, Xi Liu, Jiajia Luo, Leyi Yang, Peng Shi   +6 more
wiley   +1 more source

Interaction between arginase and L-ornithine carbamoyltransferase in Saccharomyces cerevisiae. The regulatory sites of arginase.

, 1975
The inhibition of ornithine carbamoyltransferase by arginase in Saccharomyces cerevisiae, which is under the control or arginine and ornithine, involves a regulatory site for arginine on the arginase distinct from its catalytic site. This regulatory site
Penninckx, Michel, Michel PENNINCKX
core   +1 more source

RETRACTED: Arginase II - a new target in the development of endothelium protectors

Регуляторные исследования и экспертиза лекарственных средств, 2018
RETRACTED ARTICLEThe article describes arginase’s role in pathogenesis of endothelial dysfunction and a number of cardio-vascular diseases. Arginase catalyzes the hydrolysis of L-arginine, the substrate for nitric oxide synthesis, to L-ornithine and urea.
V. I. Yakushev, M. V. Pokrovsky, E. A. Beskhmelnitsyna, O. V. Myasishcheva, A. S. Litvinova, I. I. Krivoshapova, S. A. Demchenko   +6 more
doaj  

An Injectable ROS‐Responsive Nanozyme Hydrogel Regulates the Uterine Microenvironment to Prevent Intrauterine Adhesions

Advanced Science, EarlyView.
The injectable CeTA@GPP hydrogel is administered via intrauterine injection, forming a protective barrier. In the high ROS inflammatory microenvironment of injured endometrium, boronate ester cleavage triggers responsive CeTA release and local enrichment.
Peixian Cheng, Jian Song, Yuxin Li, Ming Chen, Zeshen Liang, Binyao Qiu, Xuemin Liu, Xuetao Shi, Yong Fan   +8 more
wiley   +1 more source

ERα–PADI4–CXCL8 Axis Drives MDSC‐Mediated Immune Evasion in Anaplastic Thyroid Carcinoma

Advanced Science, EarlyView.
MAPK‐driven ligand‐independent ERα activation drives PADI4 transcription and translation. This enzyme then modifies CXCL8 chemokines through citrullination, generating a potent chemoattractant gradient specifically for myeloid‐derived suppressor cells.
Dongdong Zhang, Ying Cai, Junbin Zhang, Jianyong Zhang, Ran Jing, Ming Cai   +5 more
wiley   +1 more source

Über die Arginase

, 1904
ÜBER DIE ARGINASE Details: Zeitschrift für physiologische Chemie: 1.1877-20.1895 Hoppe-Seyler's Zeitschrift für physiologische Chemie: 21.1895- 112.1921 (-) Hoppe-Seyler's Zeitschrift für Physiologische Chemie (41) (a0000) Über die ...
Kossel, A. H. D. Dakin
core   +1 more source

Arginase and vascular aging

Journal of Applied Physiology, 2008
Vascular and associated ventricular stiffness is one of the hallmarks of the aging cardiovascular system. Both an increase in reactive oxygen species production and a decrease in nitric oxide (NO) bioavailability contribute to the endothelial dysfunction that underlies this vascular stiffness, independent of other age-related vascular pathologies such ...
Lakshmi, Santhanam, David W, Christianson, Daniel, Nyhan, Dan E, Berkowitz   +3 more
openaire   +3 more sources