Results 51 to 60 of about 3,066 (177)

The SBT6.1 subtilase processes the GOLVEN1 peptide controlling cell elongation [PDF]

, 2016
Maturation of GLV signaling peptides requires two SBT6 subtilases. SBT6 proteolytic activity is further regulated by the Serpin1 inhibitor, implying a complex network that controls cell elongation in Arabidopsis.The GOLVEN (GLV) gene family encode small ...
Beeckman, Tom, De Jaeger, Geert, Eeckhout, Dominique, Fernandez Salina, Ana, Ghorbani, Sarieh, Hilson, Pierre, Hoogewijs, Kurt, Inzé, Annelies, Kawa, Dorota, Madder, Annemieke, Pecenkova, Tamara, Van Breusegem, Frank   +11 more
core   +4 more sources

Debittering and Masking Soy Peptides for Oral Consumption and Immune‐Boosting Function

Journal of Food Biochemistry, Volume 2026, Issue 1, 2026.
Soy peptides (SPs) have been extensively studied with an emphasis on their immune‐boosting effects and production‐associated bitterness. This associated bitterness affects SPs’ oral consumption despite their bioactivities. In this review, the immune‐boosting functions, factors affecting bitterness, and consumers’ perceptions of SPs are explored ...
Wei Li, Chaoling Wen, Opeyemi Joshua Olatunji, Chi Ching Lee, Tolulope Joshua Ashaolu, Anupama Bose   +5 more
wiley   +1 more source

Amyloid Beta in Alzheimer's Disease: Mechanisms, Biomarker Potential, and Therapeutic Targets

CNS Neuroscience &Therapeutics, Volume 31, Issue 12, December 2025.
The limited clinical efficacy of anti‐Aβ antibodies has challenged the Aβ hypothesis, compelling the integration of key mechanisms—including neuroinflammation, mitochondrial dysfunction, oxidative stress, and post‐translational modifications of Aβ—into a revised model of Alzheimer's disease.
Shamseddin Ahmadi, Shiler Khaledi, Kimia Ahmadi, Kambiz Hassanzadeh   +3 more
wiley   +1 more source

THE CONCISE GUIDE TO PHARMACOLOGY 2017/18:Enzymes [PDF]

, 2017
The Concise Guide to PHARMACOLOGY 2017/18 provides concise overviews of the key properties of nearly 1800 human drug targets with an emphasis on selective pharmacology (where available), plus links to an open access knowledgebase of drug targets and ...
,, Alexander, Stephen Ph, Davies, Jamie A, Fabbro, Doriano, Faccenda, Elena, Harding, Simon D, Kelly, Eamonn, Marrion, Neil V, Pawson, Adam J, Peters, John A, Sharman, Joanna L, Southan, Christopher   +11 more
core   +15 more sources

Intervertebral Disc Proteoglycans: Multifunctional Tissue Stabilizing and Instructional Cell Regulatory Proteins That Control Tissue Homeostasis

JOR SPINE, Volume 8, Issue 4, December 2025.
Matrix and cell‐associated proteoglycans are important tissue‐stabilizing, weight‐bearing, and tension‐resisting proteins in the intervertebral disc. Their glycosaminoglycan components have growth factor binding and cell‐instructive properties that allow cells to regulate tissue composition and function.
James Melrose
wiley   +1 more source

Proteases of haematophagous arthropod vectors are involved in blood-feeding, yolk formation and immunity : a review [PDF]

, 2017
Ticks, triatomines, mosquitoes and sand flies comprise a large number of haematophagous arthropods considered vectors of human infectious diseases. While consuming blood to obtain the nutrients necessary to carry on life functions, these insects can ...
A Ali, A Borges-Veloso, A Estrela, A Fontaine, A Mulenga, A Mulenga, A Mulenga, A Santos, A Schwarz, A Seixas, A Seixas, AA Rascón, AB Estrela, AC Bahia, AC Barnard, AF Rowley, AH Kollien, AL Williamson, AR Khan, AS Raikhel, AV Graça-Souza, BM Christensen, C Balczun, C Barillas-Mury, C Gaboriaud, C Logullo, Carla Nunes de Araújo, CC Hsu, CC Hsu, CE Cruz, CH Kim, CN Araújo de, CV Barillas-Mury, D Boldbaatar, D Borovsky, D Feder, D Feder, D Sojka, D Sojka, D Sojka, D Sojka, D Sojka, D Sojka, D Sojka, D Trevisan-Silva, DE Sonenshine, DP Oldiges, DS Buarque, DS Silva da, E Calvo, E Calvo, E Calvo, E Faudry, E Goulielmaki, EC Borges, EL Telleria, EL Telleria, ES Garcia, FA Lara, FG Noriega, FG Noriega, FG Noriega, FL Watson, Flávia Nader Motta, G Bian, G Dias-Lopes, G Renard, G Renard, G Ribeiro, GM Attardo, GR Garcia, H Mehlhorn, HM Müller, HM Müller, IM Francischetti, IM Francischetti, Izabela M. Dourado Bastos, J Chmelar, J Chmelař, J Isoe, J Kotál, J Leyria, J Mendiola, J Rivera, J Vizioli, Jaime M. Santana, JAT Dow, JG Houseman, JM Anderson, JM Ramalho-Ortigão, JM Ribeiro, JM Ribeiro, JM Ribeiro, JM Ribeiro, JM Ribeiro, JM Ribeiro, JMC Ribeiro, JMC Ribeiro, K Uchida, K Yamaji, KA Edgar, L Cerenius, L Cerenius, L Feitosa, L Gupta, L Liu, L Saboia-Vahia, LA Abreu, Lehane, LM Liu, M Abdul Alim, M Delcroix, M Horn, M Kazimírová, M Lehane, M Motobu, MA Alim, MA Alim, MC Brandon, MH Castro de, MH Sorgine, MJ Gorman, MJ Gorman, N Ruttayaporn, ND Rawlings, ND Rawlings, O Hajdušek, P Bork, P Sriwichai, Paula Beatriz Santiago, PB Santiago, PF Pimenta, PJ Waniek, PM Moolhuijzen, Q Jiang, R Amino, R Graf, R Graf, RB Silveira da, RB Silveira da, RW Almeida de, S Imamura, S Karim, S Tsakas, SA Armitage, Sébastien Charneau, T Hatta, T Lopez-Ordoñez, T Masaki, T Miyoshi, T Miyoshi, T Miyoshi, T Okamoto, T Okamoto, TC Assumpção, TC Assumpção, TC Assumpção, TF Huang, V Urbanová, WL Cho, WL Cho, World Health Organization, X Guo, X Nirmala, X Yu, XL Xu, Y Decrem, Y Dong, Y Schlein, Yanna Reis Praça, Z Franta, Z Franta, Z Shen, Ž Radulović   +173 more
core   +2 more sources

Characterization of Cytokine Treatment on Human Pancreatic Islets by Top‐Down Proteomics

PROTEOMICS, Volume 25, Issue 24, Page 55-66, December 2025.
ABSTRACT Type 1 diabetes (T1D) results from autoimmune‐mediated destruction of insulin‐producing β cells in the pancreatic islet. This process is modulated by pro‐inflammatory cytokine signaling, which has been previously shown to alter protein expression in ex vivo islets.
Ashley N. Ives, Tyler J. Sagendorf, Lorenz Nierves, Tai‐Tu Lin, Ercument Dirice, Rohit N. Kulkarni, Ljiljana Paša‐Tolić, Wei‐Jun Qian, James M. Fulcher   +8 more
wiley   +1 more source

Functional variant of the carboxypeptidase M (CPM) gene may affect silica-related pneumoconiosis susceptibility by its expression: a multistage case-control study. [PDF]

, 2019
ObjectivesIn a genome-wide association study, we discovered chromosome 12q15 (defined as rs73329476) as a silica-related pneumoconiosis susceptibility region. However, the causal variants in this region have not yet been reported.MethodsWe systematically
Chu, Minjie, Gao, Yuexia, Huang, Qiqing, Lian, Yulong, Lu, Yihua, Sang, Lingli, Tian, Tian, Wang, Wei, Wu, Jianqing, Wu, Shuangshuang, Xiao, Jing, Yi, Min, Yu, Yuhui, Yuan, Weiwei, Zhang, Mingjiong, Zhang, Zuo-Feng, Zhuang, Xun   +16 more
core  

Opportunities When Chemistry Meets Biology in Catalysis and Synthesis

Transformative Chemistry, Volume 1, Issue 1, December 2025.
Biosynthesis and chemical synthesis possess complementary strengths and limitations. Integrating these two systems across multiple levels offers opportunities for molecular synthesis to become highly efficient, precise, versatile, and scalable in the future, while also ensuring environmental compatibility and resource renewability.
Xiao Xiao, Xinyi Ren, Baoguo Zhao, Xiaoguang Lei, Wen Liu, Kuiling Ding   +5 more
wiley   +1 more source

The Concise Guide to PHARMACOLOGY 2025/26: Enzymes

British Journal of Pharmacology, Volume 182, Issue S1, Page S307-S403, December 2025.
The Concise Guide to Pharmacology 2025/26 marks the seventh edition in this series of biennial publications in the British Journal of Pharmacology. Presented in landscape format, the guide provides a comparative overview of the pharmacology of drug target families. The concise nature of the Concise Guide refers to the style of presentation, being clear,
Stephen P. H. Alexander, Doriano Fabbro, Alasdair J. Gibb, Eamonn Kelly, Alistair A. Mathie, Chloe J. Peach, Emma L. Veale, Jane F. Armstrong, Elena Faccenda, Simon D. Harding, Christopher Southan, Jamie A. Davies, Stephanie Annett, Detlev Boison, Kathryn Elisa Burns, Carmen Dessauer, Jürg Gertsch, Nuala Ann Helsby, Angelo A. Izzo, Rennolds Ostrom, Ester Pagano, Andreas Papapetropoulos, Nigel J. Pyne, Susan Pyne, Tracy Robson, Roland Seifert, Johannes‐Peter Stasch, Csaba Szabo, Mario van der Stelt, Albert van der Vliet, Val Watts, Szu Shen Wong   +31 more
wiley   +1 more source