Results 61 to 70 of about 40,449 (228)

Pharmacologic management of nocturnal polyuria: a contemporary assessment of efficacy, safety, and progress toward individualized treatment

Therapeutic Advances in Urology, 2021
This narrative review synthesizes current evidence on the medical management of nocturnal polyuria, including antidiuretic replacement therapy as well as other emerging modalities, with particular emphasis on areas of active investigation and future ...
Thomas F. Monaghan, Jeffrey P. Weiss, Karel Everaert, Alan J. Wein   +3 more
doaj   +1 more source

Renal pericytes: regulators of medullary blood flow [PDF]

, 2012
Regulation of medullary blood flow (MBF) is essential in maintaining normal kidney function. Blood flow to the medulla is supplied by the descending vasa recta (DVR), which arise from the efferent arterioles of juxtamedullary glomeruli.
Agmon Y., Beach R.E., Biondi M., Burnstock G., Casellas D., Cohen H.J., Edwards R.M., Guan Z., Harrison‐Bernard L.M., Harrison‐Bernard L.M., Jamison R.L., Kreisberg M.S., Kriz W., Larson T.S., Lazarowski E.R., Lerman L.O., Majid D.S., Pallone T.L., Rouget C., Seldin D.W., Stern M.D., Strick D.M., Takenaka T., Takezawa K., Turner M.R., Unwin R.J., Yamagishi S., Yang S.   +27 more
core   +1 more source

PD‐1/PD‐L1 in Hepatocellular Carcinoma (2014–2024): A Combined Macro and Micro Analysis of Immunotherapy Implications

iNew Medicine, EarlyView.
ABSTRACT Hepatocellular carcinoma (HCC) represents a significant global health issue, with the PD‐1/PD‐L1 axis serving a pivotal target for immunotherapy in this malignancy. However, a comprehensive bibliometric analysis of PD‐1/PD‐L1 research in HCC is lacking.
Xingyu Zhu, Lin Tang, Hongyan Li, Hao Li, Jiamei Wang   +4 more
wiley   +1 more source

Maternal glucocorticoids have persistent effects on offspring social phenotype irrespective of opportunity for social buffering

Journal of Animal Ecology, EarlyView.
This study tests whether early‐life maternal association buffers offspring from the effects of prenatal stress in a facultatively social lizard. Despite clear effects of maternal glucocorticoids on growth and social behaviour, social associations did not mitigate these effects, revealing limits to social buffering in this species.
Kirsty J. MacLeod, Alix Bouffet‐Halle, Erik Wapstra, Tobias Uller, Geoffrey M. While   +4 more
wiley   +1 more source

Asymptomatic meningitis diagnosed by positron emission tomography in a patient with syndrome of inappropriate antidiuretic hormone secretion: a case report

Journal of Medical Case Reports, 2021
Background Syndrome of inappropriate antidiuretic hormone secretion can be caused by arginine-vasopressin-producing tumors or enhanced arginine vasopressin secretion from the posterior pituitary gland due to central nervous system disorders and ...
Masanori Hasebe, Jun Shirakawa, Daisuke Miyashita, Rieko Kunishita, Mayu Kyohara, Tomoko Okuyama, Yu Togashi, Yasuo Terauchi   +7 more
doaj   +1 more source

Use of 'Vaptans' in treatment of hyponatremia

Türk Kardiyoloji Derneği Arşivi, 2015
Hyponatremia is the most prevalent electrolyte imbalance, and may be present in up to 30% of hospitalized patients. It is an important predictor of in-hospital mortality.
Aslı Tanındı, Hasan Fehmi Töre
doaj   +1 more source

Compartmentalisation in cAMP signalling: A phase separation perspective

British Journal of Pharmacology, EarlyView.
Cells rely on precise spatiotemporal control of signalling pathways to ensure functional specificity. The compartmentalisation of cyclic AMP (cAMP) and protein kinase A (PKA) signalling enables distinct cellular responses within a crowded cytoplasmic space.
Milda Folkmanaite, Manuela Zaccolo
wiley   +1 more source

Strategies for discontinuing vasopressin and norepinephrine during the recovery phase of shock: a single-center retrospective study

Journal of Intensive Care
Background The optimal strategy for discontinuing arginine vasopressin and norepinephrine in patients recovering from shock remains uncertain. Although prior studies have suggested a higher risk of hypotension when arginine vasopressin is discontinued ...
Shiho Suganuma, Shigehiko Uchino, Seiya Nishiyama, Yusuke Sasabuchi, Shinshu Katayama   +4 more
doaj   +1 more source

Retention of differentiated properties in an established dog kidney epithelial cell line (MDCK). [PDF]

, 1979
Madin-Darby canine kidney (MDCK) cells grown in tissue culture have the morphological properties of distal tubular epithelial cells, form tight junctions, and lack several proximal tubular enzyme markers.
Chuman, LM, Rindler, MJ, Saier, MH, Shaffer, L   +3 more
core  

Plant organelle C‐to‐U RNA editing factors can operate successfully in yeast (Saccharomyces cerevisiae) as an easily amenable eukaryotic system for their functional analysis

The FEBS Journal, EarlyView.
Plant‐type pentatricopeptide repeat proteins capable of C‐to‐U RNA editing perform faithfully when expressed in a new heterologous system, the yeast Saccharomyces cerevisiae. They were tested with constitutive and inducible expression and with a set of different solubility tags. PPR56, PPR65, and PPR78 from P.
Shyam Ramanathan, Annika Hanraths, Jingchan Xie, Mareike Schallenberg‐Rüdinger, Volker Knoop   +4 more
wiley   +1 more source