Results 141 to 150 of about 47,693 (305)

RNAi technology development for weed control: all smoke and no fire?

Pest Management Science, Volume 81, Issue 7, Page 3430-3436, July 2025.
Despite the potential of Spray‐Induced Gene Silencing in weed management several critical points such as molecular target, weed species of interest as well as delivery techniques need to be addressed. Abstract RNA interference (RNAi) technology, specifically Spray‐Induced Gene Silencing (SIGS), holds potential as an innovative approach for selective ...
Silvia Panozzo, Andrea Milani, Serena Bordignon, Laura Scarabel, Serena Varotto   +4 more
wiley   +1 more source

Structure and Function of Argonaute Proteins [PDF]

Structure, 2005
Argonaute (Ago) family proteins are multidomain proteins expressed in prokaryotic and eukaryotic organisms. In eukaryotes, Ago proteins are most well known for their roles in RNA silencing. In prokaryotes, the functions of Ago proteins are unknown, but based on their similarity to eukaryotic Ago proteins, they could be involved in nucleic acid-directed
openaire   +3 more sources

Argonaute bypasses cellular obstacles without hindrance during target search

Nature Communications, 2019
Argonaute protein is loaded with small RNA and scans long stretch of sequences to find complementary target sites. Here, using single-molecule FRET and kinetic modelling, the authors showed that prokaryotic Argonaute protein binds target DNA loosely and ...
Tao Ju Cui, Misha Klein, Jorrit W. Hegge, Stanley D. Chandradoss, John van der Oost, Martin Depken, Chirlmin Joo   +6 more
doaj   +1 more source

Short prokaryotic Argonaute systems trigger cell death upon detection of invading DNA

Cell, 2022
Balwina Koopal, A. Potočnik, S. Mutte, Cristian Aparicio-Maldonado, S. Lindhoud, J. Vervoort, Stan J. J. Brouns, D. C. Swarts   +7 more
semanticscholar   +1 more source

Phenotypic continuum and poor intracytoplasmic sperm injection intracytoplasmic sperm injection prognosis in patients harboring HENMT1 variants

Andrology, Volume 13, Issue 5, Page 1137-1148, July 2025.
Abstract Background Small RNAs interacting with PIWI (piRNAs) play a crucial role in regulating transposable elements and translation during spermatogenesis and are essential in male germ cell development. Disruptions in the piRNA pathway typically lead to severe spermatogenic defects and thus male infertility. The HENMT1 gene is a key player in piRNAs
Zeina Wehbe, Anne‐Laure Barbotin, Angèle Boursier, Caroline Cazin, Jean‐Pascal Hograindleur, Marie Bidart, Emeline Fontaine, Pauline Plouvier, Florence Puch, Véronique Satre, Christophe Arnoult, Selima Fourati Ben Mustapha, Raoudha Zouari, Nicolas Thierry‑Mieg, Pierre F. Ray, Zine‑Eddine Kherraf, Charles Coutton, Guillaume Martinez   +17 more
wiley   +1 more source

Argonaute proteins [PDF]

Current Biology, 2011
Cenik, Elif Sarinay, Zamore, Phillip D.
openaire   +3 more sources

The Modern Argonauts

ACADEMIA. The magazine of the Polish Academy of Sciences
Myths link us all together, across countries and generations. That is why classical mythology is being incorporated into an educational curriculum designed to better equip young people to navigate the challenges of today’s world.
openaire   +2 more sources

Structural basis for the recognition of guide RNA and target DNA heteroduplex by Argonaute

Nature Communications, 2016
Argonaute proteins are important in the silencing machinery with some regulatory RNAs. Here, the authors solve the structure of an argonaute protein in complex with both the guide RNA and target DNA and propose a mechanism for their recognition.
Tomohiro Miyoshi, Kosuke Ito, Ryo Murakami, Toshio Uchiumi   +3 more
doaj   +1 more source

Rapid intraspecific evolution of miRNA and siRNA genes in the mosquito Aedes aegypti.

PLoS ONE, 2012
RNA silencing, or RNA interference (RNAi) in metazoans mediates development, reduces viral infection and limits transposon mobility. RNA silencing involves 21-30 nucleotide RNAs classified into microRNA (miRNA), exogenous and endogenous small interfering
Scott A Bernhardt, Mark P Simmons, Ken E Olson, Barry J Beaty, Carol D Blair, William C Black   +5 more
doaj   +1 more source

Simple sequence repeats and their expansions: role in plant development, environmental response and adaptation

New Phytologist, Volume 247, Issue 2, Page 504-517, July 2025.
Summary Repetitive DNA is a feature of all organisms, ranging from archaea and plants to humans. DNA repeats can be seen both in coding and in noncoding regions of the genome. Due to the recurring nature of the sequences, simple DNA repeats tend to be more prone to errors during replication and repair, resulting in variability in their unit length ...
Sridevi Sureshkumar, Aaryan Chhabra, Ya‐Long Guo, Sureshkumar Balasubramanian   +3 more
wiley   +1 more source