Results 141 to 150 of about 43,543 (282)

An Argonaute-Like Protein Is Required for Meiotic Silencing [PDF]

, 2003
Dong W. Lee, Robert Pratt, Malcolm Thomas McLaughlin, Rodolfo Aramayo   +3 more
openalex   +1 more source

Design Strategies for Novel Lipid Nanoparticle for mRNA Vaccine and Therapeutics: Current Understandings and Future Perspectives

MedComm, Volume 6, Issue 10, October 2025.
This review summarizes strategies to optimize lipid nanoparticles (LNPs) for improved targeting, endosomal escape, and safety. It highlights mRNA design, alternative delivery systems, and recent therapeutic advances across infectious diseases, cancer, and drug applications.
Xiaochi Li, Junli Li, Jiazheng Wei, Weixin Du, Cheng Su, Xiaobin Shen, Aihua Zhao, Miao Xu   +7 more
wiley   +1 more source

VCP Machinery Mediates Autophagic Degradation of Empty Argonaute

Cell Reports, 2019
Summary: The Argonaute subfamily of proteins (AGO) loads microRNAs (miRNAs) to form the effector complex that mediates target gene silencing. Empty AGO, but not miRNA-loaded AGO, is selectively degraded across species.
Hotaka Kobayashi, Keisuke Shoji, Kaori Kiyokawa, Lumi Negishi, Yukihide Tomari   +4 more
doaj   +1 more source

TbAGO1, an argonaute protein required for RNA interference, is involved in mitosis and chromosome segregation in Trypanosoma brucei. [PDF]

, 2003
Mickaël Durand‐Dubief, Philippe Bastin   +1 more
openalex   +1 more source

Crystal Structure of A. aeolicus Argonaute, a Site-Specific DNA-Guided Endoribonuclease, Provides Insights into RISC-Mediated mRNA Cleavage [PDF]

, 2005
Yuren Adam Yuan, Yi Pei, Jinbiao Ma, Vitaly Kuryavyi, Maria Zhadina, Gunter Meister, Hongying Chen, Zbigniew Dauter, Thomas Tuschl, Dinshaw J. Patel   +9 more
openalex   +1 more source

Human mitochondrial tRNA^Met is exported to the cytoplasm and associates with the Argonaute 2 protein [PDF]

, 2005
Elisavet Maniataki, Zissimos P. Mourelatos   +1 more
openalex   +1 more source

Slicer and the Argonautes [PDF]

Biophysical Journal, 2014
Faehnle, Christopher R., Elkayam, Elad, Haase, Astrid D., Hannon, Gregory J., Joshua-Tor, Leemor   +4 more
openaire   +1 more source

The RNA silencing endonuclease Argonaute 2 mediates specific antiviral immunity in Drosophila melanogaster [PDF]

, 2006
Ronald P. van Rij, María-Carla Saleh, Bassam Berry, Catherine K. Foo, Andrew Houk, Christophe Antoniewski, Raul Andino   +6 more
openalex   +1 more source

Genome-wide Integrative Analysis of Zika-Virus-Infected Neuronal Stem Cells Reveals Roles for MicroRNAs in Cell Cycle and Stemness. [PDF]

, 2019
Zika virus (ZIKV) infection is implicated in severe fetal developmental disorders, including microcephaly. MicroRNAs (miRNAs) post-transcriptionally regulate numerous processes associated with viral infection and neurodegeneration, but their ...
Dang, Jason W, Qin, Yue, Rana, Tariq M, Tiwari, Shashi Kant   +3 more
core  

Molecular characterization of PgAGO, a novel conifer gene of the ARGONAUTE family expressed in apical cells and required for somatic embryo development in spruce [PDF]

, 2006
Muhammad Tahir, Debbie A. Law, Claudio Stasolla   +2 more
openalex   +1 more source