Results 21 to 30 of about 22,965 (136)
Argonaute proteins - Methods and protocols
European Journal of Histochemistry, 2012 Before reading these few lines reviewing the Argonaute family proteins (what they are and what they do) I strongly advise the reader to go through both the greek myth and two posters: Production and actions of small RNAs by V.
Manuela Monti
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mBio, 2022 The Argonaute proteins are present in all three domains of life, which are archaea, bacteria, and eukarya. Unlike the eukaryotic Argonaute proteins, which use small RNA guides to target mRNAs, some prokaryotic Argonaute proteins (pAgos) use a small DNA ...
Jiani Xing +7 more
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Argonaute proteins: potential biomarkers for human colon cancer
BMC Cancer, 2010 Background Although Argonaute proteins are considered to play important roles in stem cell self-renewal, RNA interference (RNAi) and translational regulation, relatively little is known about their functions in human disease.
Gao Hengjun +3 more
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Nitro Reduction‐Based RNA Control and Ultrafast Release
Angewandte Chemie, EarlyView.A chemical RNA caging–uncaging strategy based on nitro reduction is described. Nitroaryl groups introduced via acylation temporarily block the functions of diverse RNAs in vitro and in living cells. Treatment with a diboronic acid–bipyridine mixture rapidly reduces the nitro groups, releasing RNAs and restoring their activity.
Yiran Zhao +6 more
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From transcription to translation: new insights in the structure and function of Argonaute protein
Biomolecular Concepts, 2012 Argonaute proteins play a central role in gene silencing pathways mediated by small RNA molecules. The ancestral function of small RNA-dependent silencing is related to genome protection against parasitic nucleic acids, such as transposons and viruses ...
Giorgi Corinna +2 more
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Domain motions of Argonaute, the catalytic engine of RNA interference
BMC Bioinformatics, 2007 Background The Argonaute protein is the core component of the RNA-induced silencing complex, playing the central role of cleaving the mRNA target. Visual inspection of static crystal structures already has enabled researchers to suggest conformational ...
Wall Michael E +2 more
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Variation and Evolution in the Glutamine-Rich Repeat Region of Drosophila Argonaute-2
G3: Genes, Genomes, Genetics, 2016 RNA interference pathways mediate biological processes through Argonaute-family proteins, which bind small RNAs as guides to silence complementary target nucleic acids .
William H. Palmer, Darren J. Obbard
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Structural basis for the recognition of guide RNA and target DNA heteroduplex by Argonaute
Nature Communications, 2016 Argonaute proteins are important in the silencing machinery with some regulatory RNAs. Here, the authors solve the structure of an argonaute protein in complex with both the guide RNA and target DNA and propose a mechanism for their recognition.
Tomohiro Miyoshi +3 more
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An NCBP3-Domain Protein Mediates Meiotic Silencing by Unpaired DNA
G3: Genes, Genomes, Genetics, 2020 In the filamentous fungus Neurospora crassa, genes unpaired during meiosis are silenced by a process known as meiotic silencing by unpaired DNA (MSUD).
Erin C. Boone +10 more
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Zdorovʹe Rebenka, 2022 The scientific review presents the mechanisms of action of cytoplasmic miRNAs, namely the relationship between miRNA and mRNA molecules and the influence of miRNAs on translation.
A.E. Abaturov, V.L. Babуch
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