Results 91 to 100 of about 79,506 (261)

Argumentation schemes as a way of arguments studies

open access: yesPhilosophy Journal, 2021
The paper investigates argument (argumentation) schemes that are used in the theory of argumentation for analyzing everyday reasoning. Such schemes should be understood as structures representing the most general types of argument. Today they are studied not only from theoretical perspectives but also in relation to their application in education and ...
openaire   +2 more sources

Redox regulation meets metabolism: targeting PRDX2 to prevent hepatocellular carcinoma

open access: yesMolecular Oncology, EarlyView.
PRDX2 acts as a central redox hub linking metabolic dysfunction‐associated steatohepatitis (MASH) to hepatocellular carcinoma (HCC). In normal hepatocytes, PRDX2 maintains redox balance and metabolic homeostasis under oxidative stress. In contrast, during malignant transformation, PRDX2 promotes oncogenic signaling, stemness, and tumor initiation ...
Naroa Goikoetxea‐Usandizaga   +2 more
wiley   +1 more source

Proceedings ICPW'07: 2nd International Conference on the Pragmatic Web, 22-23 Oct. 2007, Tilburg: NL [PDF]

open access: yes, 2007
Proceedings ICPW'07: 2nd International Conference on the Pragmatic Web, 22-23 Oct.

core  

Targeting p38α in cancer: challenges, opportunities, and emerging strategies

open access: yesMolecular Oncology, EarlyView.
p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley   +1 more source

„Sprechen Sie Deutsch? A. Merkel Nori Daugiau Vokiečių Kalbos Europoje“ (Delfi, 19.06.2013): The Image of German in Lithuanian Media Discourse

open access: yesDarnioji daugiakalbystė, 2018
The paper aims to analyze the attitudes to German language in the Lithuanian public discourse. Texts written on this topic and chosen for the analysis appeared in two news portals – the national news portal delfi.lt and the regional news portal ...
Eidukevičienė Rūta
doaj   +1 more source

Abstract Argumentation Scheme Frameworks [PDF]

open access: yes, 2008
This paper presents an approach to modelling and reasoning about arguments that exploits and combines two of the most popular mechanisms used within computational modelling of argumentation: argumentation schemes and abstract argumentation frameworks. Our proposal combines the desirable properties of each by representing the components of argumentation
Katie Atkinson, Trevor Bench-Capon
openaire   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

Argumentation Schemes for Argument from Analogy

open access: yes, 2014
In this paper I show how there are two different argumentation schemes for argument from analogy, and show by means of examples how each scheme applies to different cases in its own distinctive way. One scheme is based on similarity, while the other scheme is based on factors shared or not shared by two cases that are being compared.
openaire   +2 more sources

Argumentative Evidences Classification and Argument Scheme Detection Using Tree Kernels [PDF]

open access: yesProceedings of the 6th Workshop on Argument Mining, 2019
The purpose of this study is to deploy a novel methodology for classifying different argumentative support (supporting evidences) in arguments, without considering the context. The proposed methodology is based on the idea that the use of Tree Kernel algorithms can be a good way to discriminate between different types of argumentative stances without ...
openaire   +3 more sources

ATG4B is required for mTORC1‐mediated anabolic activity and is associated with clinical outcomes in non‐small cell lung cancer

open access: yesFEBS Open Bio, EarlyView.
The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan   +6 more
wiley   +1 more source

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