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Aristolochic acid: What urologists should know

Archivio Italiano di Urologia e Andrologia, 2022
To the Editor, Aristolochic acid is one of major causes for upper tract urothelial carcinoma, especially in younger population. While it is mentioned as a cause in guidelines, little is actually known about the toxin by urologists. We are aiming in our letter to provide some direct and clear information to ourselves that would help us to know more ...
M. Thangavelu, Asmaa Ismail, Ahmed S. Zakaria, Hazem Elmansy, Walid Shahrour, Owen Prowse, Ahmed Kotb   +6 more
openalex   +4 more sources

Aristolochic Acid Induced Suicidal Erythrocyte Death [PDF]

Kidney & Blood Pressure Research, 2014
Background/Aims: Aristolochic Acid, a component of Aristolochia plants, has been shown to cause acute kidney injury, renal aristolochic acid nephropathy, Balkan endemic nephropathy, and urothelial carcinoma.
Abaid Malik, Rosi Bissinger, Salvatrice Calabrò, Caterina Faggio, Kashif Jilani, Florian Lang   +5 more
doaj   +4 more sources

Overview of aristolochic acid nephropathy: an update [PDF]

Kidney Research and Clinical Practice, 2023
Aristolochic acid nephropathy (AAN) is a rapidly progressive renal interstitial fibrosis caused by medical or environmental exposure to aristolochic acid (AA).
Qingqing Zhou, Lei Jiang, Tao Su, Gang Liu, Li Yang   +4 more
doaj   +3 more sources

Aristolochic acid I exposure decreases oocyte quality

Frontiers in Cell and Developmental Biology, 2022
Oocyte quality is a determinant of a successful pregnancy. The final step of oocyte development is oocyte maturation, which is susceptible to environmental exposures.
Weidong Li, Weidong Li, Jiaming Zhang, Xiaoxia Yu, Fei Meng, Ju Huang, Liangran Zhang, Liangran Zhang, Shunxin Wang, Shunxin Wang, Shunxin Wang, Shunxin Wang   +11 more
doaj   +3 more sources

Aristolochic acid nephropathy [PDF]

BMJ, 2012
A disease that could be prevented through more careful regulation of herbal products More than 20 years ago a Belgian report described nine women with rapidly progressive fibrosing interstitial nephritis who either required dialysis or showed progressive renal impairment.1 All of the women had taken a slimming regimen that included herbs of the ...
Goekmen, M. Refik, Lord, Graham M.
  +8 more sources

Study of the Contents of Analogues of Aristolochic Acid in Houttuynia cordata by Ultra-High Performance Liquid Chromatography Tandem Mass Spectrometry

Foods, 2022
In this study, a new and simple method was established for the simultaneous determination of analogues of aristolochic acids (aristolochic acid I, aristolochic acid II, aristolactam I and aristolactam AII) in Houttuynia cordata by ultra-high performance ...
Xuan Yu, Yuan Gao, Ying Xu, Xian Guo, Lan Guo, Ting Tan, Fan Liu, Yiqun Wan   +7 more
doaj   +1 more source

Computational Analysis of Naturally Occurring Aristolochic Acid Analogues and Their Biological Sources

Biomolecules, 2021
Aristolochic acids are known for nephrotoxicity, and implicated in multiple cancer types such as hepatocellular carcinomas demonstrated by recent studies.
Tingjun Xu, Weiming Chen, Junhong Zhou, Jingfang Dai, Yingyong Li, Yingli Zhao   +5 more
doaj   +1 more source

Preventive effect of icariin on transition from acute kidney injury to chronic kidney disease in mouse model

Shanghai Jiaotong Daxue xuebao. Yixue ban, 2023
Objective·To investigate the effect of icariin on the transition from acute kidney disease (AKI) to chronic kidney disease (CKD) in mice and the possible mechanism.Methods·C57BL/6 mice were intraperitoneally injected with aristolochic acid for 2 weeks to
XIE Lin, CHENG Ye, ZHENG Qimin, ZHANG Xi, FU Lili, CHEN Min, WANG Yi, MEI Changlin, XIE Jingyuan, GU Xiangchen   +9 more
doaj   +1 more source

Proteogenomic characterization of cholangiocarcinoma

Hepatology, EarlyView., 2022
Proteogenomic characterization of cholangiocarcinoma with therapeutic strategies Abstract Background and Aims Cholangiocarcinoma (CCA) is a highly heterogeneous cancer with limited understanding and few effective therapeutic approaches. We aimed at providing a proteogenomic CCA characterization to inform biological processes and treatment ...
Mengjie Deng, Peng Ran, Lingli Chen, Yunzhi Wang, Zixiang Yu, Ke Cai, Jinwen Feng, Zhaoyu Qin, Yanan Yin, Subei Tan, Yang Liu, Chen Xu, Guoming Shi, Yuan Ji, Jian‐Yuan Zhao, Jian Zhou, Jia Fan, Yingyong Hou, Chen Ding   +18 more
wiley   +1 more source

Preventing Aristolochic Acid Nephropathy [PDF]

Clinical Journal of the American Society of Nephrology, 2015
Reports of an epidemic of rapidly progressive fibrosing interstitial nephritis first surfaced in the early 1990s in a cohort of Belgium women ([1][1]). The causative agent was found to be aristolochic acid ([2][2]), a family of compounds found in the plant genus Aristolochiacaea , including ...
Anandagoda, Nelomi, Lord, Graham M.
openaire   +3 more sources