Results 11 to 20 of about 2,142 (181)

Molecular Characterization of Microrna Interference and Aristolochic Acid Intoxication Found in Upper Tract Urothelial Carcinoma in Patients with Balkan Endemic Nephropathy: A Systematic Review of the Current Literature

Balkan Journal of Medical Genetics, 2022
The term “aristolochic acid nephropathy” (AAN) is used to include any form of toxic interstitial nephropathy that is caused either by ingestion of plants containing aristolochic acids (AA) or by the environmental contaminants in food such as in Balkan ...
Bašić D, Ignjatović I, Janković Veličković Lj, Veljković A   +3 more
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Rapid Analysis of Aristolochic Acid Analogues in Traditional Chinese Patent Medicine by LC-MS/MS

Journal of Analytical Methods in Chemistry, 2020
Aristolochic acids have been demonstrated to have renal toxicity, cause carcinogenesis, and may cause gene mutations. A series of risk control measurements have been adopted worldwide since 1990s.
Jing Liu, Yang Liu, Yingxue Wu, Zhong Dai, Shuangcheng Ma   +4 more
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De novo upper tract urothelial carcinoma after renal transplantation: a single-center experience in China

BMC Urology, 2023
Highlights Both higher tumor staging and positive lymph node status were associated with a worse cancer-specific survival in patients with post-transplant de novo UTUC. Aristolochic acid was associated with multifocality of tumors and higher incidence of
Shixin Li, Jian Zhang, Ye Tian, Yichen Zhu, Yuwen Guo, Zhipeng Wang, Yang Yang, Guangpu Ding, Jun Lin   +8 more
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Isolation of Aristolochic Acids from Aristolochia Bracteolata and Studies of their Antioxidant Activities

Sultan Qaboos University Journal for Science, 2004
The isolation and structural elucidation of aristolochic acid-A and aristolochic acid-D from Omani Aristolochia bracteolata plant is reported. Antioxidant activities of these two natural products were evaluated for their capacity to reduce Mo(VI) to Mo(V)
Saleh Al-Busafi, Munir Al-Harthi, Bushra Al-Sabahi   +2 more
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Two New Aristolochic Acid Analogues from the Roots of Aristolochia contorta with Significant Cytotoxic Activity

Molecules, 2020
Twelve compounds, including two new aristolochic acid analogues with a formyloxy moiety (9–10) and 10 known aristolochic acid derivates (1–8 and 11–12), were obtained from the roots of Aristolochiacontorta.
Hong-Jian Ji, Jia-Yuan Li, Shi-Fei Wu, Wen-Yong Wu, Chang-Liang Yao, Shuai Yao, Jian-Qing Zhang, De-An Guo   +7 more
doaj   +1 more source

Parametric MRI Detects Aristolochic Acid Induced Acute Kidney Injury

Tomography, 2022
Exposure to aristolochic acid (AA) is of increased concern due to carcinogenic and nephrotoxic effects, and incidence of aristolochic acid nephropathy (AAN) is increasing.
Yingjie Mei, Guixiang Yang, Yihao Guo, Kaixuan Zhao, Shuyu Wu, Zhongbiao Xu, Shan Zhou, Chenggong Yan, Erdmann Seeliger, Thoralf Niendorf, Yikai Xu, Yanqiu Feng   +11 more
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Unambiguous detection of multiple TP53 gene mutations in AAN-associated urothelial cancer in Belgium using laser capture microdissection. [PDF]

PLoS ONE, 2014
In the Balkan and Taiwan, the relationship between exposure to aristolochic acid and risk of urothelial neoplasms was inferred from the A>T genetic hallmark in TP53 gene from malignant cells.
Selda Aydin, Anne-France Dekairelle, Jérôme Ambroise, Jean-François Durant, Michel Heusterspreute, Yves Guiot, Jean-Pierre Cosyns, Jean-Luc Gala   +7 more
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Lycopene attenuates the inflammation and apoptosis in aristolochic acid nephropathy by targeting the Nrf2 antioxidant system

Redox Biology, 2022
Lycopene (LYC) is a carotenoid, has antioxidant properties. This study investigated whether lycopene attenuates aristolochic acids (AAs) -induced chronic kidney disease.
Yu Wang, Zhihui Liu, Jun Ma, Qingyang Xv, Hongxin Gao, Hang Yin, Ge Yan, Xiaowen Jiang, Wenhui Yu   +8 more
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Aristolochic acid nephropathy: A worldwide problem [PDF]

Kidney International, 2008
Aristolochic acid nephropathy (AAN), a progressive renal interstitial fibrosis frequently associated with urothelial malignancies, was initially reported in a Belgian cohort of more than 100 patients after the intake of slimming pills containing a Chinese herb, Aristolochia fangchi.
Debelle, Frédéric, Vanherweghem, Jean-Louis, Nortier, Joëlle   +2 more
openaire   +2 more sources

Worldwide research trends on aristolochic acids (1957-2017): Suggestions for researchers.

PLoS ONE, 2019
Aristolochic acids and their derivatives are components of many traditional medicines that have been used for thousands of years, particularly in Asian countries.
Qiang Zhou, Jin Pei, Josiah Poon, Alexander Y Lau, Li Zhang, Yuhua Wang, Chang Liu, Linfang Huang   +7 more
doaj   +1 more source