Results 21 to 30 of about 2,142 (181)

In situ metabolomics in nephrotoxicity of aristolochic acids based on air flow-assisted desorption electrospray ionization mass spectrometry imaging

open access: yesActa Pharmaceutica Sinica B, 2020
Understanding of the nephrotoxicity induced by drug candidates is vital to drug discovery and development. Herein, an in situ metabolomics method based on air flow-assisted desorption electrospray ionization mass spectrometry imaging (AFADESI-MSI) was ...
Zhonghua Wang   +7 more
doaj   +1 more source

Aristolochic acid nephropathy - still real danger

open access: yesJournal of Education, Health and Sport, 2022
Arystolocholic acid nephropathy is chronic kidney disease caused by the use of substances of natural origin that contain arystolocholic acid. The effects of their use are arystolochic acid nephropathies, which include "Chinese Herbs" nephropathy.
Rafal Oleszczuk   +4 more
doaj   +1 more source

Update of aristolochic acid nephropathy in Korea [PDF]

open access: yesThe Korean Journal of Internal Medicine, 2018
The true incidence of aristolochic acid nephropathy (AAN) is thought to be underestimated because numerous ingredients known or suspected to contain aristolochic acid (AA) are used in traditional medicine in Korea.We collected data on cases of AAN since 1996 via a database in Korea.
Ban, Tae Hyun   +12 more
openaire   +2 more sources

Interactions of Human Organic Anion Transporters With Aristolochic Acids

open access: yesJournal of Pharmacological Sciences, 2010
Aristolochic acids (AAs), contained in Chinese herbal preparations, have been considered to induce nephropathy. In order to elucidate the molecular mechanisms of AA-induced nephrotoxicity, we have elucidated the interaction of human organic anion ...
Ellappan Babu   +8 more
doaj   +1 more source

Aristolochic acids affect the feeding behaviour and development of Battus polydamas archidamas larvae (Lepidoptera: Papilionidae: Troidini)

open access: yesEuropean Journal of Entomology, 2009
The feeding behaviour of specialist butterflies may be affected by the mechanical and chemical characteristics of the tissues of their host-plants. Larvae of the butterfly, Battus polydamas archidamas feed only on Aristolochia chilensis, which contains ...
Carlos F. PINTO   +3 more
doaj   +1 more source

Aristolochic acid causes albuminuria by promoting mitochondrial DNA damage and dysfunction in podocyte. [PDF]

open access: yesPLoS ONE, 2013
Aristolochic acid nephropathy, initially found in patients intaking of slimming herbs containing aristolochic acid (AA), was previously considered as a progressive renal interstitial fibrosis and urothelial malignancy.
Yang Zhou   +5 more
doaj   +1 more source

Estudo químico e atividade antibacteriana do caule de Aristolochia esperanzae kuntze (Aristolochiaceae) Chemical study and antibacterial activity of stem of Aristolochia esperanzae Kuntze (Aristolochiaceae)

open access: yesQuímica Nova, 2010
From the ethanolic extract of the stem of A. esperanzae ethyl and methyl fatty acid esters, fatty acids, aristolochic I and II acids, and β-cubebin were isolated.
Alison G. Pacheco   +7 more
doaj   +1 more source

An oviposition stimulant binding protein in a butterfly Immunohistochemical localization and electrophysiological responses to plant compounds

open access: yesCommunicative & Integrative Biology, 2009
Oviposition is evoked by plant compounds, which are recognized by chemoreceptive organs of insects. The swallowtail butterfly, Atrophaneura alcinous, oviposits its eggs on the host plant, Aristolochia debilis, in the presence of only two stimulating ...
Kazuko Tsuchihara   +3 more
doaj   +1 more source

Detection and Removal of Aristolochic Acid in Natural Plants, Pharmaceuticals, and Environmental and Biological Samples: A Review

open access: yesMolecules, 2023
Aristolochic acids (AAs) are a toxic substance present in certain natural plants. Direct human exposure to these plants containing AAs leads to a severe and irreversible condition known as aristolochic acid nephropathy (AAN).
Changhong Wang   +5 more
doaj   +1 more source

Metabolomics insights into activated redox signaling and lipid metabolism dysfunction in chronic kidney disease progression

open access: yesRedox Biology, 2016
Early detection is critical in prevention and treatment of kidney disease. However currently clinical laboratory and histopathological tests do not provide region-specific and accurate biomarkers for early detection of kidney disease.
Hua Chen   +8 more
doaj   +1 more source

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